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Completed Phase 2 Interventional Results available

My Pathway: A Study Evaluating Herceptin/Perjeta, Tarceva, Zelboraf/Cotellic, Erivedge, Alecensa, and Tecentriq Treatment Targeted Against Certain Molecular Alterations in Participants With Advanced Solid Tumors

ClinicalTrials.gov ID: NCT02091141

Public ClinicalTrials.gov record NCT02091141. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 24, 2026, 5:04 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

My Pathway: An Open-Label Phase IIa Study Evaluating Trastuzumab/Pertuzumab, Erlotinib, Vemurafenib/Cobimetinib, Vismodegib, Alectinib, and Atezolizumab in Patients Who Have Advanced Solid Tumors With Mutations or Gene Expression Abnormalities Predictive of Response to One of These Agents

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This multicenter, non-randomized, open-label study will evaluate the efficacy and safety of six treatment regimens in participants with advanced solid tumors for whom therapies that will convey clinical benefit are not available and/or are not suitable options per the treating physician's judgment.

Study identification

NCT ID
NCT02091141
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Genentech, Inc.
Industry
Enrollment
673 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 14, 2014 (Actual)
Primary completion
May 24, 2023 (Actual)
Completion
May 24, 2023 (Actual)
Last update posted
Jul 23, 2024

2014 – 2023

United States locations

U.S. sites
60
U.S. states
25
U.S. cities
50
Facility City State ZIP Site status
Western Regional Medical Center at Cancer Treatment Centers of America Goodyear Arizona 85338 —
Mayo Clinic Arizona Phoenix Arizona 85259 —
Highlands Oncology Group Springdale Arkansas 72762 —
Science 37, Inc Culver City California 90230 —
City of Hope Comprehensive Cancer Center Duarte California 91010 —
Moores UCSD Cancer Center; Dept Clinical Trials Office La Jolla California 92093-0698 —
Eisenhower Medical Center Rancho Mirage California 92270 —
Stanford Comprehensive Cancer Center Stanford California 94305 —
Kaiser Permanente - Vallejo Vallejo California 94589 —
University of Colorado Aurora Colorado 80045-2517 —
SCRI Florida Cancer Specialists South Fort Myers Florida 33916 —
Mayo Clinic Jacksonville Florida 32224 —
Florida Hospital Cancer Inst; Memorial System Onc Clin Rsch Orlando Florida 32804 —
Florida Cancer Specialist, North Region St. Petersburg Florida 33705 —
Florida Cancer Specialists, Research Department West Palm Beach Florida 33401 —
University Cancer & Blood Center, LLC; Research Athens Georgia 30607 —
Northeast Georgia Medical Center; Oncology Research Dept-5C Gainesville Georgia 30501 —
Southeastern Regional Medical Center, Inc. Newnan Georgia 30265 —
Northwestern University; Robert H. Lurie Comp Can Ctr; Northwestern Medicine Development Inst Chicago Illinois 60611 —
University Of Chicago Medical Center; Section Of Hematology/Oncology Chicago Illinois 60637 —
Midwestern Regional Med Center Zion Illinois 60099 —
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore Maryland 21287 —
Mayo Foundation Rochester Minnesota 55905 —
Research Medical Center - Antibiotic Research Associates, Inc. Kansas City Missouri 64132 —
Memorial Sloan Kettering - Monmouth Middletown New Jersey 07748 —
University of New Mexico Comprehensive Cancer Center Albuquerque New Mexico 87102 —
University of New Mexico Comprehensive Cancer Center - Albuquerque Cedar Street; Drug Shipment Albuquerque New Mexico 87106 —
University of New Mexico Comprehensive Cancer Center - Albuquerque Lang NE; Drug Shipment Albuquerque New Mexico 87109 —
University of New Mexico Albuquerque New Mexico 87131 —
San Juan Oncology Associates Farmington New Mexico 87401 —
Memorial Sloan Kettering Cancer Center at Westchester Harrison New York 10604 —
Weill Cornell Univ Medical Ctr; Breast Cancer Center New York New York 10021 —
Herbert Irving Comprehensive Cancer Center; Herbert Irving Pavillion New York New York 10032 —
Memorial Sloan Kettering Cancer Center New York New York 10065 —
Univ No Carolina School of Med; Physicians Office Bldg Chapel Hill North Carolina 27599-7305v —
Duke University Medical Center Durham North Carolina 27710 —
Wake Forest Univ Health Svcs; Internal Medicine Winston-Salem North Carolina 27157 —
Sanford Roger Maris Cancer Center Fargo North Dakota 58102 —
Oncology Hematology Care Inc Cincinnati Ohio 45242 —
Cleveland Clinic Cleveland Ohio 44106 —
University Hospitals of Cleveland Cleveland Ohio 44106 —
University of Oklahoma Health Sciences Center Oklahoma City Oklahoma 73104 —
Providence Portland Medical Center Portland Oregon 97213 —
Abramson Cancer Center Philadelphia Pennsylvania 19104 —
Thomas Jefferson University Hospital Philadelphia Pennsylvania 19107 —
Eastern Regional Medical Ctr Philadelphia Pennsylvania 19124 —
UPMC - Hillman Cancer Center Pittsburgh Pennsylvania 15232 —
Abington Mem Hosp-Abington; Rose. Can Ctr,Gyn Onc Ins Willow Grove Pennsylvania 19090 —
Sanford Cancer Cnt Onco Clinic Sioux Falls South Dakota 57104 —
Sarah Cannon Research Institute / Tennessee Oncology Chattanooga Tennessee 37404 —
West Clinic Germantown Tennessee 38138 —
Tennessee Cancer Specialists Knoxville Tennessee 37920 —
Tennessee Oncology - Nashville Nashville Tennessee 37203 —
Vanderbilt Ingram Cancer Clinic Nashville Tennessee 37232 —
The Center for Cancer and Blood Disorders - Fort Worth Fort Worth Texas 76104 —
MD Anderson Houston Texas 77030 —
Virginia Cancer Institute Richmond Virginia 23229 —
Northwest Medical Specialties Tacoma Washington 98405 —
University of Wisconsin Madison Wisconsin 53705 —
Medical College of Wisconsin Milwaukee Wisconsin 53226 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02091141, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 23, 2024 · Synced Oct 24, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02091141 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →