Safety Study Of Tofacitinib Versus Tumor Necrosis Factor (TNF) Inhibitor In Subjects With Rheumatoid Arthritis
Public ClinicalTrials.gov record NCT02092467. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
PHASE 3B/4 RANDOMIZED SAFETY ENDPOINT STUDY OF 2 DOSES OF TOFACITINIB IN COMPARISON TO A TUMOR NECROSIS FACTOR (TNF) INHIBITOR IN SUBJECTS WITH RHEUMATOID ARTHRITIS
Study identification
- NCT ID
- NCT02092467
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Lead sponsor
- Pfizer
- Industry
- Enrollment
- 4,372 participants
Conditions and interventions
Conditions
Interventions
- adalimumab Biological
- etanercept Biological
- tofacitinib Drug
Biological · Drug
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 13, 2014
- Primary completion
- Jul 21, 2020
- Completion
- Jul 21, 2020
- Last update posted
- Aug 16, 2021
2014 – 2020
United States locations
- U.S. sites
- 142
- U.S. states
- 34
- U.S. cities
- 113
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham (UAB), Arthritis Clinical Intervention Program | Birmingham | Alabama | 35294-7201 | — |
| Rheumatology Associates of North Alabama, PC | Huntsville | Alabama | 35801 | — |
| Clinical and Translational Research Center of Alabama, PC | Tuscaloosa | Alabama | 35406 | — |
| Southern Arizona VA Health Care System (SAVAHCS) | Tucson | Arizona | 85723 | — |
| University of Arizona Clinical and Translational Science Research Center | Tucson | Arizona | 85724 | — |
| CHI St. Vincent Medical Group Hot Springs | Hot Springs | Arkansas | 71913 | — |
| Arthritis And Rheumatism Associates LLC | Jonesboro | Arkansas | 72401 | — |
| Medvin Clinical Research | Covina | California | 91722 | — |
| Med Investigations, Inc. | Fair Oaks | California | 95628 | — |
| Talbert Medical Group | Huntington Beach | California | 92646 | — |
| University of California, San Diego (UCSD)- Perlman Ambulatory Clinic | La Jolla | California | 92037 | — |
| Valerius Medical Group And Research Center Of Greater Long Beach, Inc. | Long Beach | California | 90806 | — |
| ProHealth Partners | Long Beach | California | 90808 | — |
| Keck Medicine of USC | Los Angeles | California | 90033 | — |
| California Medical Research Associates Inc | Northridge | California | 91324 | — |
| Desert Medical Advances | Palm Desert | California | 92260 | — |
| Medvin Clinical Research | Placentia | California | 92870 | — |
| Sierra Rheumatology, Inc. | Roseville | California | 95661 | — |
| San Diego Arthritis Medical Clinic | San Diego | California | 92108 | — |
| Dr. Orrin M. Troum, Md And Medical Associates | Santa Monica | California | 90404 | — |
| Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center | Torrance | California | 90502 | — |
| Harbor UCLA Medical Center | Torrance | California | 90509 | — |
| Robin K. Dore M.D., Inc. | Tustin | California | 92780 | — |
| Medvin Clinical Research | Van Nuys | California | 91405 | — |
| Ventura Clinical Trials | Ventura | California | 93003 | — |
| Desert Valley Medical Group | Victorville | California | 92395 | — |
| Medvin Clinical Research | Whittier | California | 90602 | — |
| Arthritis Associates and Osteoporosis Center of Colorado Springs | Colorado Springs | Colorado | 80920 | — |
| Howard University Hospital | Washington D.C. | District of Columbia | 20060 | — |
| RASF-Clinical Research Center, Inc | Boca Raton | Florida | 33486 | — |
| Bay Area Arthritis and Osteoporosis | Brandon | Florida | 33511 | — |
| Arthritis & Rheumatism Associates (Private Practice) | Clearwater | Florida | 33756 | — |
| Florida Clinical Research Group (Administrative Office) | Clearwater | Florida | 33759 | — |
| Dr.Robert W. Levin MDOffice of | Clearwater | Florida | 33765 | — |
| International Medical Research | Daytona Beach | Florida | 32117 | — |
| Centre for Rheumatology, Immunology and Arthritis | Fort Lauderdale | Florida | 33309 | — |
| University of Florida - Rheumatology at ACC | Jacksonville | Florida | 32207 | — |
| University of Florida College of Medicine, Jacksonville - Rheumatology Research | Jacksonville | Florida | 32207 | — |
| Doctors Research Institute | Miami | Florida | 33145 | — |
| Center for Arthritis and Rheumatic Diseases | Miami | Florida | 33173 | — |
| San Marcus Research Clinic | Miami Lakes | Florida | 33014 | — |
| Ocala Rheumatology Research Center | Ocala | Florida | 34474 | — |
| Advanced Clinical Research of Orlando | Ocoee | Florida | 34761 | — |
| Arthritis & osteoporosis treatment center,PA | Orange Park | Florida | 32073 | — |
| Rheumatology Associates of Central Florida, PA | Orlando | Florida | 32806 | — |
| Omega Research Consultants, LLC | Orlando | Florida | 32810 | — |
| Millennium Research | Ormond Beach | Florida | 32174 | — |
| Arthritis Center, Inc. | Palm Harbor | Florida | 34684 | — |
| Arthritis Research of Florida, Inc. | Palm Harbor | Florida | 34684 | — |
| Advanced Medical Research Center | Port Orange | Florida | 32127 | — |
| Advanced Urgent Care | Port Orange | Florida | 32127 | — |
| USF Health Morsani Center for Advanced Healthcare | Tampa | Florida | 33612 | — |
| Florida Medical Clinic, P.A. | Zephyrhills | Florida | 33542 | — |
| Arthritis and Rheumatology of GA, P.C. | Atlanta | Georgia | 30342 | — |
| Medical Associates of North Georgia - Rheumatology | Canton | Georgia | 30115 | — |
| Office of Jefrey D. Lieberman, MD, PC | Decatur | Georgia | 30033 | — |
| Coeur D'Alene Arthritis Clinic | Coeur d'Alene | Idaho | 83814 | — |
| Quincy Medical Group | Quincy | Illinois | 62301 | — |
| Springfield Clinic | Springfield | Illinois | 62702 | — |
| Diagnostic Rheumatology and Research PC | Indianapolis | Indiana | 46227 | — |
| MidWest Clinical Research, LLC | Overland Park | Kansas | 66209 | — |
| Professional Research Network of Kansas, LLC | Wichita | Kansas | 67205-1138 | — |
| Arthritis and Diabetes Clinic, Inc. | Monroe | Louisiana | 71203 | — |
| Klein & Associates, M.D.,P.A. | Cumberland | Maryland | 21502 | — |
| Arthritis Treatment Center | Frederick | Maryland | 21702 | — |
| Klein & Associates, MD, PA | Hagerstown | Maryland | 21740 | — |
| The Center for Rheumatology and Bone Research, a division of Arthritis and Rheumatism Associates, PC | Wheaton | Maryland | 20902 | — |
| Phase III Clinical Research | Fall River | Massachusetts | 02720 | — |
| UMass Memorial Medical Center, Memorial Campus | Worcester | Massachusetts | 01605 | — |
| Bronson Healthcare Group | Battle Creek | Michigan | 49015 | — |
| Bronson Rheumatology Specialists | Kalamazoo | Michigan | 49007 | — |
| Jasper Clinic, Inc. | Kalamazoo | Michigan | 49007 | — |
| Western Michigan University Homer Stryker M.D. School of Medicine Center for Clinical Research | Kalamazoo | Michigan | 49008 | — |
| Borgess Medical Center | Kalamazoo | Michigan | 49048 | — |
| Borgess Research Institute | Kalamazoo | Michigan | 49048 | — |
| June DO,PC | Lansing | Michigan | 48910 | — |
| Shores Rheumatology P.C. | Saint Clair Shores | Michigan | 48081 | — |
| St. Paul Rheumatology, PA | Eagan | Minnesota | 55121 | — |
| Center for Diagnostic Imaging | Mendota Heights | Minnesota | 55118 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Kansas City Internal Medicine | Kansas City | Missouri | 64114 | — |
| Clinvest Research, LLC | Springfield | Missouri | 65810 | — |
| Glacier View Research Institute | Kalispell | Montana | 59901 | — |
| Physician Research Collaboration, LLC | Lincoln | Nebraska | 68516 | — |
| Westroads Clinical Research, Inc. | Omaha | Nebraska | 68114 | — |
| University of Nevada School of Medicine | Las Vegas | Nevada | 89102 | — |
| Steinberg Diagnostics | Las Vegas | Nevada | 89109 | — |
| EKSAKTI, LLC (dba: Eksakti Clinical Research) | Las Vegas | Nevada | 89128 | — |
| Arthritis Center Of Reno | Reno | Nevada | 89502 | — |
| Nashua Rheumatology | Nashua | New Hampshire | 03060 | — |
| Summit Medical Group | Clifton | New Jersey | 07012 | — |
| Weill Cornell Physicians at Brooklyn Heights | Brooklyn | New York | 11201 | — |
| Northwell Health Division of Rheumatology | Great Neck | New York | 11021 | — |
| NYU Langone Rheumatology Associates Long Island. | Lake Success | New York | 11042 | — |
| EmergeOrtho,P.A. | Durham | North Carolina | 27704 | — |
| Physicians East, PA | Greenville | North Carolina | 27834 | — |
| PMG Research of Hickory LLC | Hickory | North Carolina | 28601 | — |
| Frycare outpatient imaging Center | Hickory | North Carolina | 28602 | — |
| PMG Research of Hickory, LLC | Hickory | North Carolina | 28602 | — |
| PMG Research Inc., d/b/a PMG Research of Piedmont HealthCare | Statesville | North Carolina | 28625 | — |
| Carolina Arthritis Associates | Wilmington | North Carolina | 28401 | — |
| St. Alexius Medical Center | Bismarck | North Dakota | 58501 | — |
| Trinity Health Center - Medical Arts | Minot | North Dakota | 58701 | — |
| Cincinnati Rheumatic Disease Study Group, Inc. | Cincinnati | Ohio | 45242 | — |
| STAT Research, Inc. | Dayton | Ohio | 45417 | — |
| Health Research of Oklahoma | Oklahoma City | Oklahoma | 73103 | — |
| Oklahoma Medical Research Foundation (OMRF) | Oklahoma City | Oklahoma | 73104 | — |
| Lynn Health Science Institute | Oklahoma City | Oklahoma | 73112 | — |
| Altoona Center for Clinical Research | Duncansville | Pennsylvania | 16635 | — |
| The Arthritis Group | Philadelphia | Pennsylvania | 19152 | — |
| UPMC Arthritis and Autoimmunity Clinic | Pittsburgh | Pennsylvania | 15213 | — |
| UPMC Lupus Center of Excellence | Pittsburgh | Pennsylvania | 15213 | — |
| Clinical Research Center of Reading, LLC | Wyomissing | Pennsylvania | 19610 | — |
| Rheumatology Associates, P.A. | Charleston | South Carolina | 29407 | — |
| Innovative Clinical Research, LLC | Greenville | South Carolina | 29601 | — |
| Piedmont Arthritis Clinic, PA | Greenville | South Carolina | 29601 | — |
| Articluaris Healthcare Group d/b/a ACME Research | Orangeburg | South Carolina | 29118 | — |
| Articularis Healthcare Group, Inc d/b/a Low Country Rheumatology | Summerville | South Carolina | 29486 | — |
| West Tennessee Research Institute | Jackson | Tennessee | 38305 | — |
| Rheumatology Consultants, PLLC | Knoxville | Tennessee | 37909 | — |
| Dr. Ramesh C. Gupta MD, Office of | Memphis | Tennessee | 38119 | — |
| Center For Inflammatory Disease | Nashville | Tennessee | 37203 | — |
| Amarillo Center for Clinical Research, Ltd. | Amarillo | Texas | 79124 | — |
| Austin Regional Clinic | Austin | Texas | 78731 | — |
| Trinity Universal Research Associates, Inc | Carrollton | Texas | 75007 | — |
| Pioneer Research Solutions, Inc. | Cypress | Texas | 77429 | — |
| Baylor Scott and White Research Institute / Arthritis Care and Research Center | Dallas | Texas | 75231 | — |
| Arthritis Centers of Texas | Dallas | Texas | 75246 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | — |
| Accurate Clinical Management, LLC | Houston | Texas | 77004 | — |
| Rheumatic Disease Clinical Research Center | Houston | Texas | 77004 | — |
| Accurate Clinical Research, Inc. | Houston | Texas | 77034 | — |
| Houston Institute for Clinical Research | Houston | Texas | 77074 | — |
| Accurate Clinical Management, LLC | Houston | Texas | 77084 | — |
| Medical Center Research, LLC | Houston | Texas | 77089 | — |
| Accurate Clinical Research, Inc. | League City | Texas | 77573 | — |
| Arthritis and Osteoporosis Associates, LLP | Lubbock | Texas | 79424 | — |
| Southwest Rheumatology Research, LLC | Mesquite | Texas | 75150 | — |
| Trinity Universal Research Associates, Inc. | Plano | Texas | 75024 | — |
| Center for Arthritis and Rheumatic Diseases, PC | Chesapeake | Virginia | 23320 | — |
| Center for Arthritis and Rheumatic Diseases, P.C. | Suffolk | Virginia | 23435 | — |
| Rheumatic Disease Center | Glendale | Wisconsin | 53217 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 203 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02092467, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 16, 2021 · Synced May 5, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02092467 live on ClinicalTrials.gov.