Extension Study to Assess the Efficacy and Safety of Repeat Treatment With Rituximab (MabThera) in Participants With Active Rheumatoid Arthritis (RA)
Public ClinicalTrials.gov record NCT02093026. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-label Study of the Efficacy and Safety of Re-treatments With Rituximab (MabThera®/Rituxan®) in Patients With Active Rheumatoid Arthritis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will assess the long-term safety and efficacy of repeat treatment courses of rituximab, in combination with methotrexate in a disease-modifying anti-rheumatic drug (DMARD) inadequate responder population of participants who were previously randomized into studies WA16291 (NCT02693210) or WA17043/U2644g (NCT00074438). The study permits multiple re-treatments until the protocol-defined end-of-treatment date (31 December 2011). Participants will then enter a safety follow-up (SFU) period of at least 48 weeks. This will provide at least 7 years follow-up data on all participants initially randomized into WA16291 or WA17043/U2644g. Approximately 600 participants will potentially be eligible to enter this open label extension study from their respective feeder studies.
Study identification
- NCT ID
- NCT02093026
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 465 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 21 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 2002 (Type not available)
- Primary completion
- Dec 2012 (Actual)
- Completion
- Dec 2012 (Actual)
- Last update posted
- Mar 13, 2017
2002 – 2012
United States locations
- U.S. sites
- 42
- U.S. states
- 24
- U.S. cities
- 39
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Birmingham | Alabama | 35294 | — |
| Not listed | Peoria | Arizona | 85381 | — |
| Not listed | Little Rock | Arkansas | 72205 | — |
| Not listed | La Jolla | California | 92037 | — |
| Not listed | Long Beach | California | 92813 | — |
| Not listed | Rancho Mirage | California | 92270 | — |
| Not listed | San Diego | California | 92108 | — |
| Not listed | Colorado Springs | Colorado | 80920 | — |
| Not listed | Aventura | Florida | 33180 | — |
| Not listed | Boca Raton | Florida | 33486 | — |
| Not listed | Fort Lauderdale | Florida | 33334 | — |
| Not listed | Largo | Florida | 33773 | — |
| Not listed | South Miami | Florida | 33143 | — |
| Not listed | Boise | Idaho | 83702 | — |
| Not listed | Chicago | Illinois | 60611 | — |
| Not listed | Chicago | Illinois | 60637 | — |
| Not listed | Indianapolis | Indiana | 46202-5149 | — |
| Not listed | Indianapolis | Indiana | 46260 | — |
| Not listed | Boston | Massachusetts | 02215 | — |
| Not listed | Minneapolis | Minnesota | 55416 | — |
| Not listed | St Louis | Missouri | 63141 | — |
| Not listed | Lebanon | New Hampshire | 03756 | — |
| Not listed | Voorhees Township | New Jersey | 08043 | — |
| Not listed | Great Neck | New York | 11021 | — |
| Not listed | Plainview | New York | 11803 | — |
| Not listed | Rochester | New York | 14618 | — |
| Not listed | Smithtown | New York | 11787 | — |
| Not listed | Greenville | North Carolina | 27834 | — |
| Not listed | Winston-Salem | North Carolina | 27157 | — |
| Not listed | Beachwood | Ohio | 44122 | — |
| Not listed | Dayton | Ohio | 45402 | — |
| Not listed | Mayfield | Ohio | 44143 | — |
| Not listed | Tulsa | Oklahoma | 74104 | — |
| Not listed | Tulsa | Oklahoma | 74135 | — |
| Not listed | Portland | Oregon | 97239 | — |
| Not listed | Duncansville | Pennsylvania | 16635 | — |
| Not listed | Dallas | Texas | 75231 | — |
| Not listed | Houston | Texas | 77074 | — |
| Not listed | Salt Lake City | Utah | 84132 | — |
| Not listed | Seattle | Washington | 98104 | — |
| Not listed | Glendale | Wisconsin | 53217 | — |
| Not listed | Wausau | Wisconsin | 54401 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 50 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02093026, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 13, 2017 · Synced Oct 28, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02093026 live on ClinicalTrials.gov.