A Study of the Efficacy and Safety of Re-treatments With Rituximab in Patients With Active Rheumatoid Arthritis Who Have Had an Inadequate Response to Anti-tnfa Therapies

ClinicalTrials.gov ID: NCT02097745

Public ClinicalTrials.gov record NCT02097745. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Oct 31, 2026, 6:13 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open Label Study of the Efficacy and Safety of Re-treatments With Rituximab (MabThera/Rituxan) in Patients With Active Rheumatoid Arthritis Who Have Had an Inadequate Response to Anti-TNFa Therapies

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study will assess the long-term safety and efficacy of repeating treatment with MabThera, in combination with methotrexate and steroids, in patients who were previously randomized into MabThera study WA17042. The anticipated time on study treatment is until Mabthera is available on the local market and the target sample size is 100-500 individuals.

Study identification

NCT ID: NCT02097745
Recruitment status: Completed
Study type: Interventional
Phase: Phase 3
Lead sponsor: Hoffmann-La Roche; Industry
Enrollment: 341 participants

Conditions and interventions

Conditions

Rheumatoid Arthritis

Interventions

methotrexate Drug
rituximab [MabThera/Rituxan] Drug

Drug

Eligibility (public fields only)

Age range: 18 Years to 80 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jun 2004 (Type not available)
Primary completion: Jun 2013 (Actual)
Completion: Jun 2013 (Actual)
Last update posted: Nov 3, 2016

2004 – 2013

United States locations

U.S. sites: 59
U.S. states: 24
U.S. cities: 50

Facility	City	State	ZIP	Site status
Not listed	Mesa	Arizona	85208	—
Not listed	Paradise Valley	Arizona	85253	—
Not listed	Tucson	Arizona	85724	—
Not listed	Little Rock	Arkansas	72205	—
Not listed	Fullerton	California	92835	—
Not listed	Los Angeles	California	90045	—
Not listed	Los Angeles	California	90048	—
Not listed	Pasadena	California	91105	—
Not listed	Rancho Mirage	California	92270	—
Not listed	Santa Maria	California	93454	—
Not listed	Danbury	Connecticut	06810	—
Not listed	Boca Raton	Florida	33486	—
Not listed	Delray Beach	Florida	33484	—
Not listed	Fort Lauderdale	Florida	33334	—
Not listed	Jupiter	Florida	33458	—
Not listed	Orlando	Florida	32806	—
Not listed	Boise	Idaho	83702	—
Not listed	Coeur d'Alene	Idaho	83814	—
Not listed	Meridian	Idaho	83642	—
Not listed	Chicago	Illinois	60612	—
Not listed	Chicago	Illinois	60637	—
Not listed	Indianapolis	Indiana	46202-5149	—
Not listed	Indianapolis	Indiana	46260	—
Not listed	Shreverport	Louisiana	71103	—
Not listed	Baltimore	Maryland	21224	—
Not listed	Boston	Massachusetts	02215	—
Not listed	Kalamazoo	Michigan	49048	—
Not listed	Lansing	Michigan	48910	—
Not listed	Rochester	Minnesota	55905	—
Not listed	St Louis	Missouri	63110	—
Not listed	St Louis	Missouri	63141	—
Not listed	Albany	New York	12206	—
Not listed	Manhasset	New York	11030	—
Not listed	New York	New York	10003	—
Not listed	Rochester	New York	14618	—
Not listed	Smithtown	New York	11787	—
Not listed	Chapel Hill	North Carolina	27599-7600	—
Not listed	Greenville	North Carolina	27834	—
Not listed	Cincinnati	Ohio	45267-0563	—
Not listed	Dayton	Ohio	45402	—
Not listed	Mayfield	Ohio	44143	—
Not listed	Oklahoma City	Oklahoma	73103	—
Not listed	Oklahoma City	Oklahoma	73109	—
Not listed	Tulsa	Oklahoma	74135	—
Not listed	Duncansville	Pennsylvania	16635	—
Not listed	Philadelphia	Pennsylvania	19140	—
Not listed	Philadelphia	Pennsylvania	19141	—
Not listed	Philadelphia	Pennsylvania	19152	—
Not listed	Amarillo	Texas	79124	—
Not listed	Dallas	Texas	75231	—
Not listed	Dallas	Texas	75246	—
Not listed	Houston	Texas	77074	—
Not listed	Waco	Texas	76710	—
Not listed	Salt Lake City	Utah	84132	—
Not listed	Burlington	Vermont	05401	—
Not listed	Seattle	Washington	98101	—
Not listed	Seattle	Washington	98104	—
Not listed	Spokane	Washington	99204	—
Not listed	Madison	Wisconsin	53792	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 38 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT02097745, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Nov 3, 2016 · Synced Oct 31, 2026

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02097745 live on ClinicalTrials.gov.

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