Study Of The Blood Thinner, Apixaban, For Patients Who Have An Abnormal Heart Rhythm (Atrial Fibrillation) And Expected To Have Treatment To Put Them Back Into A Normal Heart Rhythm (Cardioversion)
Public ClinicalTrials.gov record NCT02100228. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
A Phase Iv Trial To Assess The Effectiveness Of Apixaban Compared With Usual Care Anticoagulation In Subjects With Non-valvular Atrial Fibrillation Undergoing Cardioversion
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Some people can develop an abnormal heart beat known as "Atrial fibrillation" or "AF" that puts them at risk of developing clots in the heart. Those clots can travel in the blood circulation to the brain and cause a brain attack ("a stroke"). To prevent those clots forming, blood thinners (anti-coagulants) are used. Apixaban is a blood thinner that works by stopping one of the blood substances required for clotting ("Factor Xa"). It is approved and used to prevent clots forming in people with "AF". Other established blood thinners work by stopping clotting substances being made, known as "Vitamin K antagonists" or "VKAs". An example of this type is Warfarin (Coumadin). The good effects of all blood thinners are preventing clots, and they may also have bad effects of increasing the chance of bleeding. People with "AF", abnormal heart beat, may benefit from changing it back to a normal regular rhythm, known medically as "cardioversion". When this is done, people are currently most commonly treated with a "VKA" blood thinner (e.g. warfarin). The purpose of this study is to assess the good and bad effects ("efficacy" and "safety") of apixaban compared with warfarin in people with "AF" in whom an early cardioversion is planned.
Study identification
- NCT ID
- NCT02100228
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 1,500 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 14, 2014 (Actual)
- Primary completion
- Feb 8, 2017 (Actual)
- Completion
- Feb 8, 2017 (Actual)
- Last update posted
- May 23, 2018
2014 – 2017
United States locations
- U.S. sites
- 63
- U.S. states
- 21
- U.S. cities
- 35
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Brookwood Medical Center | Birmingham | Alabama | 35209 | — |
| Cardiovascular Associates of the Southeast, LLC | Birmingham | Alabama | 35243 | — |
| Integrated Medical Services, Inc./IMS Cardiology | Avondale | Arizona | 85392 | — |
| Chula Vista Cardiac Center | Chula Vista | California | 91910 | — |
| Hartford Hospital | Hartford | Connecticut | 06102 | — |
| Certified Physician Investigator Research Group LLC | Altamonte Springs | Florida | 32714 | — |
| Orlando Heart Specialists | Altamonte Springs | Florida | 32714 | — |
| The University of Chicago Medical Center Investigational Drug Service Pharmacy (office/storage) | Chicago | Illinois | 60637 | — |
| The University of Chicago Medical Center Investigational Drug Service Pharmacy | Chicago | Illinois | 60637 | — |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| Chicago Medical Research, LLC | Hazel Crest | Illinois | 60429 | — |
| Franciscan Physician Network-Indiana Heart Physicians | Indianapolis | Indiana | 46237 | — |
| Franciscan St. Francis Health | Indianapolis | Indiana | 46237 | — |
| UK Good Samaritan Medical Office Building | Lexington | Kentucky | 40508-2678 | — |
| Good Samaritan Hospital | Lexington | Kentucky | 40508-3008 | — |
| University of Kentucky Medical Center Gill Heart Institute | Lexington | Kentucky | 40536-0200 | — |
| University of Kentucky Gill Heart Institute | Lexington | Kentucky | 40536 | — |
| University of Kentucky HealthCare/Albert. B, Chandler Hospital | Lexington | Kentucky | 40536 | — |
| Aim Clinic | Louisville | Kentucky | 40202 | — |
| Cardiology Outpatient Clinic | Louisville | Kentucky | 40202 | — |
| University of Louisville Clinical Trials Unit | Louisville | Kentucky | 40202 | — |
| University of Louisville Hospital | Louisville | Kentucky | 40202 | — |
| Robley Rex VA Medical Center | Louisville | Kentucky | 40206 | — |
| Alexandria Cardiology Clinic | Alexandria | Louisiana | 71301 | — |
| University of Massachusetts Worcester Research Pharmacy | Worcester | Massachusetts | 01655 | — |
| University of Massachusetts Worcester | Worcester | Massachusetts | 01655 | — |
| William Beaumont Hospital | Royal Oak | Michigan | 48073 | — |
| Abbott Northwestern Hopsital - Allina Health System | Minneapolis | Minnesota | 55407 | — |
| Minneapolis Heart Institute Foundation | Minneapolis | Minnesota | 55407 | — |
| University of Missouri Health Care System | Columbia | Missouri | 65212 | — |
| University of Missouri Health System, Investigational Drug Serivce | Columbia | Missouri | 65212 | — |
| University of Missouri Health System | Columbia | Missouri | 65212 | — |
| Saint Luke's Lipid and Diabetes Research Center | Kansas City | Missouri | 64111 | — |
| Mercy Hospital St. Louis | St Louis | Missouri | 63141 | — |
| Electrophysiology Associates | Hackensack | New Jersey | 07601 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Robert Wood Johnson University Hospital | New Brunswick | New Jersey | 08901 | — |
| Rutgers Robert Wood Johnson Medical School Cardiovascular Institute | New Brunswick | New Jersey | 08901 | — |
| State University of New York (SUNY) Downstate Medical Center | Brooklyn | New York | 11203 | — |
| New York-Presbyterian/Queens | Flushing | New York | 11355 | — |
| Columbia University Medical Center/NY Presbyterian Hospital | New York | New York | 10032 | — |
| University of Cincinnati Medical Center | Cincinnati | Ohio | 45219 | — |
| ProMedica Physicians Cardiology | Oregon | Ohio | 43616 | — |
| ProMedica Toledo Hospital | Toledo | Ohio | 43606 | — |
| ProMedica Physicians Cardiology | Toledo | Ohio | 43615 | — |
| Hillcrest Medical Center Pharmacy | Tulsa | Oklahoma | 74104 | — |
| Oklahoma Heart Institute at Hillcrest Medical Center | Tulsa | Oklahoma | 74104 | — |
| Oklahoma Heart Institute | Tulsa | Oklahoma | 74104 | — |
| Cardiology Consultants of Philadelphia | Bristol | Pennsylvania | 19007 | — |
| Bryn Mawr Hospital | Bryn Mawr | Pennsylvania | 19010 | — |
| Bryn Mawr Medical Specialist Association | Bryn Mawr | Pennsylvania | 19010 | — |
| Penn State Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| Pennsylvania Hospital | Philadelphia | Pennsylvania | 19107 | — |
| Einstein Healthcare Network | Philadelphia | Pennsylvania | 19141 | — |
| Cardiology consultants of Philadelphia | Yardley | Pennsylvania | 19067 | — |
| Baptist Hospital of Southeast Texas - Beaumont | Beaumont | Texas | 77701 | — |
| Southeast Texas Cardiology Associates II, L.L.P. | Beaumont | Texas | 77702 | — |
| Southeast Texas Cardiology Associates II, L.L.P | Beaumont | Texas | 77702 | — |
| Southeast Texas Clinical Research Center | Beaumont | Texas | 77702 | — |
| Utah Cardiology, PC | Layton | Utah | 84041 | — |
| Cardiovascular Associates of Virginia-Bon Secours St. Mary's Hospital | Midlothian | Virginia | 23114 | — |
| St. Francis Medical Center | Midlothian | Virginia | 23114 | — |
| Dominion Cardiovascular Specialists PLLC | Richmond | Virginia | 23225 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 102 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02100228, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 23, 2018 · Synced Nov 5, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02100228 live on ClinicalTrials.gov.