A Study of the Efficacy and Safety of Etrolizumab in Participants With Ulcerative Colitis Who Have Been Previously Exposed to Tumor Necrosis Factor (TNF) Inhibitors
Public ClinicalTrials.gov record NCT02100696. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase III, Double-Blind, Placebo-Controlled, Multicenter Study of the Efficacy and Safety of Etrolizumab During Induction and Maintenance in Patients With Moderate to Severe Active Ulcerative Colitis Who Have Been Previously Exposed to TNF Inhibitors
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This Phase III, double-blind, placebo-controlled, multicenter study will investigate the efficacy and safety of etrolizumab during induction and maintenance of remission compared with placebo in the treatment of participants with moderately to severely active ulcerative colitis (UC) who have been previously exposed to TNF inhibitors.
Study identification
- NCT ID
- NCT02100696
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 609 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 21, 2014 (Actual)
- Primary completion
- Apr 16, 2020 (Actual)
- Completion
- Apr 16, 2020 (Actual)
- Last update posted
- Aug 13, 2021
2014 – 2020
United States locations
- U.S. sites
- 38
- U.S. states
- 19
- U.S. cities
- 35
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| University of California San Diego Medical Center | La Jolla | California | 92093-5354 | — |
| Clinical Applications Laboratories, Inc. | San Diego | California | 92103 | — |
| Precision Research Institute, LLC | San Diego | California | 92114 | — |
| University of California at San Francisco | San Francisco | California | 94115 | — |
| Rocky Mountain Gastroenterology Associates | Denver | Colorado | 80222 | — |
| Rocky Mountain Gastroenterology Associates, P.L.L.C.; Gastroenterology | Lakewood | Colorado | 80215 | — |
| FQL Research, LLC | Miramar | Florida | 33025 | — |
| Center For Digestive Health | Orlando | Florida | 32803 | — |
| Internal Medicine Specialists | Orlando | Florida | 32806 | — |
| Shafran Gastroenterology Center | Winter Park | Florida | 32789 | — |
| Gastroenterology Associates of Central Georgia | Macon | Georgia | 31201 | — |
| Gastrointestinal Specialists of Georgia, PC | Marietta | Georgia | 30060 | — |
| Atlanta Gastroenterology Specialists, PC | Suwanee | Georgia | 30024 | — |
| Northwestern University Feinberg School Of Medicine | Chicago | Illinois | 60611 | — |
| Southwest Gastroenterology | Oak Lawn | Illinois | 60453 | — |
| Cotton-O'Neil Clinical Research Center, Digestive Health | Topeka | Kansas | 66606 | — |
| Gastroenterology Associates, LLC | Baton Rouge | Louisiana | 70809 | — |
| Louisiana Research Center, LLC | Shreveport | Louisiana | — | — |
| Massachusetts General Hospital; Crohn's & Colitis Center | Boston | Massachusetts | 02114 | — |
| University of Michigan; Michigan Institute for Clinical and Health Research (MICHR) | Ann Arbor | Michigan | 48109 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Center for Digestive Health | Troy | Michigan | 48098 | — |
| Kansas City Research Institute, LLC | Kansas City | Missouri | 64131 | — |
| Clinica Peruano Americana S.A. | Great Neck | New York | 11021 | — |
| Weill Cornell Medical College-New York Presbyterian Hospital | New York | New York | 10021 | — |
| University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27599 | — |
| Consultants for Clinical Research Inc. | Cincinnati | Ohio | 45219 | — |
| UC Health, LLC. | Cincinnati | Ohio | 45219 | — |
| Great Lakes Gastroenterology Research, LLC | Mentor | Ohio | 44060 | — |
| Gastroenterology Center of the Midsouth, P.C. | Memphis | Tennessee | 38120 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Tyler Research Institute, LLC | Tyler | Texas | 75701 | — |
| Ericksen Research and Development | Clinton | Utah | 84015 | — |
| University of Utah School of Medicine | Salt Lake City | Utah | 84132 | — |
| Digestive and Liver Disease Specialists, Ltd. | Norfolk | Virginia | 23502 | — |
| McGuire Research Institute; Gastroenterology | Richmond | Virginia | 23249 | — |
| Washington Gastroenterology | Bellevue | Washington | 98004 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 146 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02100696, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 13, 2021 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02100696 live on ClinicalTrials.gov.