A Comparison of Fractional Flow Reserve-Guided Percutaneous Coronary Intervention and Coronary Artery Bypass Graft Surgery in Patients With Multivessel Coronary Artery Disease
Public ClinicalTrials.gov record NCT02100722. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Fractional Flow Reserve Versus Angiography for Multivessel Evaluation (FAME) 3 Trial A Comparison of Fractional Flow Reserve-Guided Percutaneous Coronary Intervention and Coronary Artery Bypass Graft Surgery in Patients With Multivessel Coronary Artery Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine whether Fractional flow reserve (FFR, (coronary pressure wire-based index for assessing the ischemic potential of a coronary lesion)-guided percutaneous coronary intervention (PCI) in patients with multivessel coronary artery disease (CAD) will result in similar outcomes to coronary artery bypass graft surgery (CABG).
Study identification
- NCT ID
- NCT02100722
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 1,500 participants
Conditions and interventions
Conditions
Interventions
- FFR guided PCI Procedure
- CABG Procedure
- Resolute Integrity Stent Device
- Resolute Onyx Stent Device
Procedure · Device
Eligibility (public fields only)
- Age range
- 21 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 24, 2014
- Primary completion
- Nov 30, 2020
- Completion
- Nov 30, 2024
- Last update posted
- Apr 6, 2026
2014 – 2024
United States locations
- U.S. sites
- 13
- U.S. states
- 11
- U.S. cities
- 12
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Palo Alto VA | Palo Alto | California | — | — |
| Stanford University | Stanford | California | 94305-2004 | — |
| Atlanta VA Medical Center | Decatur | Georgia | — | — |
| Jesse Brown VA Medical Center | Chicago | Illinois | — | — |
| University of Kansas Medical Center | Lawrence | Kansas | — | — |
| Lexinton VA | Lexington | Kentucky | — | — |
| University of Kentucky Medical Center | Lexington | Kentucky | — | — |
| Baystate Medical Center | Springfield | Massachusetts | — | — |
| HealthEast St. Joseph's Hospital | Saint Paul | Minnesota | — | — |
| Penn Presbyterian Medical Center | Philadelphia | Pennsylvania | — | — |
| Centennial Heart | Nashville | Tennessee | — | — |
| Houston Methodist Hospital | Houston | Texas | — | — |
| University of Virginia | Charlottesville | Virginia | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 33 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02100722, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 6, 2026 · Synced Sep 2, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02100722 live on ClinicalTrials.gov.