Dose Ranging Safety and Efficacy of Therapeutic HSV-2 Vaccine
Public ClinicalTrials.gov record NCT02114060. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Factorial Study to Compare the Safety and Efficacy of Varying Combinations of GEN-003 and Matrix-M2 in Subjects With Genital HSV-2 Infection
Study identification
- NCT ID
- NCT02114060
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Genocea Biosciences, Inc.
- Industry
- Enrollment
- 310 participants
Conditions and interventions
Conditions
Interventions
- GEN-003 Vaccine (30μg of each antigen) Biological
- GEN-003 Vaccine (60μg of each antigen) Biological
- Matrix-M2 Adjuvant (25μg) Biological
- Matrix-M2 Adjuvant (50μg) Biological
- Matrix-M2 Adjuvant (75μg) Biological
- Placebo Biological
Biological
Eligibility (public fields only)
- Age range
- 18 Years to 50 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 30, 2014
- Primary completion
- Jan 31, 2016
- Completion
- Jan 31, 2016
- Last update posted
- Oct 15, 2017
2014 – 2016
United States locations
- U.S. sites
- 16
- U.S. states
- 12
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama Vaccine Research Unit | Birmingham | Alabama | 35294-0006 | — |
| Medical Center for Clinical Research | San Diego | California | 92108 | — |
| Quest Clinical Research | San Francisco | California | 94115 | — |
| University of Illinois Department of Medicine | Chicago | Illinois | 60612 | — |
| Indiana University Infectious Disease Research | Indianapolis | Indiana | 46202 | — |
| The Fenway Institute | Boston | Massachusetts | 02215 | — |
| UNC Global HIV Prevention and Treatment Clinical Trials Unit | Chapel Hill | North Carolina | 27599 | — |
| Cincinnati Children's Hospital Medical Center | Cincinnati | Ohio | 45229-3039 | — |
| Westover Heights Clinic | Portland | Oregon | 97210 | — |
| Magee-Womens Hospital of UPMC | Pittsburgh | Pennsylvania | 15213 | — |
| Tekton Research | Austin | Texas | 98745 | — |
| Center for Clinical Studies - Houston | Houston | Texas | 77030 | — |
| Center for Clinical Studies | Houston | Texas | 77065 | — |
| Center for Clinical Studies - Clear Lake/Webster | Webster | Texas | 77598 | — |
| University of Utah | Salt Lake City | Utah | 84132 | — |
| UW Virology Research Clinic | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02114060, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 15, 2017 · Synced Jul 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02114060 live on ClinicalTrials.gov.