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Completed Phase 2 Interventional Results available

OnabotulinumtoxinA as Treatment for Major Depressive Disorder in Adult Females

ClinicalTrials.gov ID: NCT02116361

Public ClinicalTrials.gov record NCT02116361. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 5, 2026, 3:13 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

BOTOX® (Botulinum Toxin Type A) Purified Neurotoxin Complex as Treatment for Major Depressive Disorder in Adult Females

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study will evaluate the safety and efficacy of onabotulinumtoxinA (BOTOX®) compared with placebo as treatment for major depressive disorder (MDD) in adult females.

Study identification

NCT ID
NCT02116361
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Allergan
Industry
Enrollment
258 participants

Conditions and interventions

Interventions

Biological · Drug

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
Female
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 21, 2014
Primary completion
Aug 24, 2016
Completion
Dec 21, 2016
Last update posted
Dec 18, 2017

2014 – 2016

United States locations

U.S. sites
35
U.S. states
14
U.S. cities
32
Facility City State ZIP Site status
Woodland International Research Group Little Rock Alaska 72211
CITrials Bellflower California 90706
Radiant Research/Comprehensive Clinical Development, Inc. Cerritos California 90703
Collaborative Neuroscience Network Inc. Garden Grove California 92845
Behavioral Research Specialists, LLC Glendale California 91206
Excell Research, Inc. Oceanside California 92056
NRC Research Institute Orange California 92868
Artemis Institute for Clinical Research San Diego California 92103
Schuster Medical Research Institute Sherman Oaks California 91403
Sarkis Clinical Trials Gainesville Florida 32607
Clinical Neuroscience Solutions, Inc. Jacksonville Florida 32256
Compass Research LLC-North Clinic Leesburg Florida 34748
Research Centers of America, LLC Oakland Park Florida 33334
Clinical Neuroscience Solutions, Inc Orlando Florida 32801
Compass Research, LLC Orlando Florida 32806
Stedman Clinical Trials Tampa Florida 33613
Institute for Advanced Medical Research Alpharetta Georgia 30005
Atlanta Center for Medical Research Atlanta Georgia 30331
iResearch Atlanta, LLC Decatur Georgia 30030
Uptown Research Institute, LLC Chicago Illinois 60640
Psychiatric Medicine Associates, LLC Skokie Illinois 60076
St. Louis Clinical Trials, LLC St Louis Missouri 63141
Integrative Clinical Trials Brooklyn New York 11229
SPRI Clinical Trials Brooklyn New York 11235
Finger Lakes Clinical Research Rochester New York 14618
Midwest Clinical Research Center Dayton Ohio 45417
IPS Research Company Oklahoma City Oklahoma 73103
Oklahoma Clinical Research Center Oklahoma City Oklahoma 73112
Summit Research Network (Oregon) Inc. Portland Oregon 97210
Clinical Neuroscience Solutions, INC Memphis Tennessee 38119
KRK Medical Research Dallas Texas 75230
InSite Clinical Research DeSoto Texas 75115
Virginia Commonwealth University Clinical Research Services Unit Richmond Virginia 23298
Northwest Clinical Research Center Bellevue Washington 98007
Zain Research LLC Richland Washington 99352

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02116361, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 18, 2017 · Synced Sep 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02116361 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →