Efficacy and Safety of Extended Release and Immediate Release Febuxostat in Participants With Gout and Moderate Renal Impairment
Public ClinicalTrials.gov record NCT02128490. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Double Blind, Multicenter, Placebo Controlled Study to Evaluate the Efficacy and Safety of Febuxostat 40 mg XR, 80 mg XR, 40 mg IR and 80 mg IR in Subjects With Gout and Moderate Renal Impairment
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the efficacy and safety of febuxostat 40 mg extended release (XR) and 80 mg XR in comparison with febuxostat 40 mg immediate release (IR) and 80 mg IR, respectively, in gout participants with moderate renal impairment.
Study identification
- NCT ID
- NCT02128490
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 189 participants
Conditions and interventions
Conditions
Interventions
- Febuxostat IR Drug
- Febuxostat XR Drug
- Febuxostat placebo Drug
- Colchicine Drug
- Naproxen Drug
- Lansoprazole Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 2014 (Type not available)
- Primary completion
- Sep 2015 (Actual)
- Completion
- Oct 2015 (Actual)
- Last update posted
- Nov 3, 2016
2014 – 2015
United States locations
- U.S. sites
- 89
- U.S. states
- 26
- U.S. cities
- 78
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Birmingham | Alabama | — | — |
| Not listed | Muscle Shoals | Alabama | — | — |
| Not listed | Phoenix | Arizona | — | — |
| Benny Green MD PA Family Practice | Little Rock | Arkansas | 72223 | — |
| Not listed | Little Rock | Arkansas | — | — |
| Not listed | Bellflower | California | — | — |
| Not listed | Escondido | California | — | — |
| Not listed | Harbor City | California | — | — |
| Not listed | Huntington Park | California | — | — |
| Not listed | Irvine | California | — | — |
| Not listed | Lomita | California | — | — |
| Long Beach Center for Clinical Research | Long Beach | California | 90807 | — |
| Not listed | Long Beach | California | — | — |
| Not listed | Los Angeles | California | — | — |
| Brigid Freyne MD | Murrieta | California | 92563 | — |
| Not listed | Murrieta | California | — | — |
| Not listed | Orange | California | — | — |
| Not listed | Rancho Cucamonga | California | — | — |
| Not listed | Redondo Beach | California | — | — |
| Not listed | Sacramento | California | — | — |
| Not listed | San Jose | California | — | — |
| Not listed | San Ramon | California | — | — |
| Not listed | Clearwater | Florida | — | — |
| Not listed | Coral Gables | Florida | — | — |
| Not listed | Coral Springs | Florida | — | — |
| Riverside Clinical Research | Edgewater | Florida | 32141 | — |
| Not listed | Edgewater | Florida | — | — |
| Not listed | Hialeah | Florida | — | — |
| Not listed | Miami | Florida | — | — |
| Not listed | Miami Beach | Florida | — | — |
| Not listed | Miami Lakes | Florida | — | — |
| Not listed | Orlando | Florida | — | — |
| Not listed | Pembroke Pines | Florida | — | — |
| Not listed | Plantation | Florida | — | — |
| Not listed | Port Charlotte | Florida | — | — |
| Not listed | Saint Cloud | Florida | — | — |
| Not listed | Vero Beach | Florida | — | — |
| Not listed | Atlanta | Georgia | — | — |
| Not listed | Dunwoody | Georgia | — | — |
| Not listed | East Point | Georgia | — | — |
| Not listed | Suwanee | Georgia | — | — |
| East West Medical Research Institute | Honolulu | Hawaii | 96814 | — |
| Not listed | Honolulu | Hawaii | — | — |
| Not listed | Brownsburg | Indiana | — | — |
| Not listed | Manhattan | Kansas | — | — |
| Not listed | Wichita | Kansas | — | — |
| Not listed | Elizabethtown | Kentucky | — | — |
| Central Kentucy Reseach Associates | Lexington | Kentucky | 40509 | — |
| Not listed | Lexington | Kentucky | — | — |
| Not listed | Paducah | Kentucky | — | — |
| Not listed | Mandeville | Louisiana | — | — |
| Not listed | Metairie | Louisiana | — | — |
| Not listed | Fall River | Massachusetts | — | — |
| Not listed | Detroit | Michigan | — | — |
| Not listed | Kalamazoo | Michigan | — | — |
| Not listed | Hazelwood | Missouri | — | — |
| Not listed | Washington | Missouri | — | — |
| Not listed | Las Vegas | Nevada | — | — |
| Not listed | Albuquerque | New Mexico | — | — |
| Not listed | Columbiana | North Carolina | — | — |
| Not listed | Greensboro | North Carolina | — | — |
| Not listed | Salisbury | North Carolina | — | — |
| Not listed | Wilmington | North Carolina | — | — |
| Not listed | Fargo | North Dakota | — | — |
| Not listed | Franklin | Ohio | — | — |
| COR Clinical Research LLC | Oklahoma City | Oklahoma | 73103 | — |
| Not listed | Oklahoma City | Oklahoma | — | — |
| Not listed | Portland | Oregon | — | — |
| Not listed | Columbia | South Carolina | — | — |
| Not listed | Greer | South Carolina | — | — |
| Not listed | Old Point Station | South Carolina | — | — |
| Not listed | Clarksville | Tennessee | — | — |
| Not listed | Knoxville | Tennessee | — | — |
| Remesh C Gupta MD | Memphis | Tennessee | 38119 | — |
| Not listed | Memphis | Tennessee | — | — |
| Not listed | Austin | Texas | — | — |
| Not listed | Bellaire | Texas | — | — |
| 3rd Coast Research Associates | Corpus Christi | Texas | 78413 | — |
| Not listed | Corpus Christi | Texas | — | — |
| Not listed | Nassau Bay | Texas | — | — |
| Not listed | Plano | Texas | — | — |
| Sun Research Institute | San Antonio | Texas | 78215 | — |
| Briggs Clinical Research LLC | San Antonio | Texas | 78224 | — |
| Not listed | San Antonio | Texas | — | — |
| Not listed | Bountiful | Utah | — | — |
| Not listed | Newport News | Virginia | — | — |
| Not listed | Norfolk | Virginia | — | — |
| Not listed | Richmond | Virginia | — | — |
| Not listed | Virginia Beach | Virginia | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02128490, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 3, 2016 · Synced Oct 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02128490 live on ClinicalTrials.gov.