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Terminated Phase 1 Interventional

Sapanisertib Before and After Surgery in Treating Patients With Recurrent Glioblastoma

ClinicalTrials.gov ID: NCT02133183

Public ClinicalTrials.gov record NCT02133183. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 2:42 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Pilot Study of MLN0128 (TAK-228) in Preoperative Recurrent Glioblastoma (GBM) Patients

Study identification

NCT ID
NCT02133183
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1
Lead sponsor
National Cancer Institute (NCI)
NIH
Enrollment
40 participants

Conditions and interventions

Interventions

  • Laboratory Biomarker Analysis Other
  • Pharmacological Study Other
  • Sapanisertib Drug
  • Therapeutic Conventional Surgery Procedure

Other · Drug · Procedure

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 1, 2014
Primary completion
Jan 30, 2020
Completion
Oct 30, 2023
Last update posted
Apr 3, 2024

2014 – 2023

United States locations

U.S. sites
10
U.S. states
8
U.S. cities
9
Facility City State ZIP Site status
University of Alabama at Birmingham Cancer Center Birmingham Alabama 35233
UCLA / Jonsson Comprehensive Cancer Center Los Angeles California 90095
UCSF Medical Center-Parnassus San Francisco California 94143
Johns Hopkins University/Sidney Kimmel Cancer Center Baltimore Maryland 21287
Dana-Farber Cancer Institute Boston Massachusetts 02215
Henry Ford Hospital Detroit Michigan 48202
Wake Forest University Health Sciences Winston-Salem North Carolina 27157
Case Western Reserve University Cleveland Ohio 44106
Cleveland Clinic Foundation Cleveland Ohio 44195
University of Pittsburgh Cancer Institute (UPCI) Pittsburgh Pennsylvania 15232

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02133183, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 3, 2024 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02133183 live on ClinicalTrials.gov.

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