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Completed Phase 1 Interventional Results available

A Dose Finding Study To Evaluate Safety, Drug Interaction, Tumor Markers Of Axitinib In Combination With MK-3475 In Adult Patients With Previously Untreated Advanced Renal Cell Cancer

ClinicalTrials.gov ID: NCT02133742

Public ClinicalTrials.gov record NCT02133742. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 6, 2026, 8:50 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A PHASE 1B, OPEN LABEL, DOSE FINDING STUDY TO EVALUATE SAFETY, PHARMACOKINETICS AND PHARMACODYNAMICS OF AXITINIB (AG-013736) IN COMBINATION WITH PEMBROLIZUMAB (MK-3475) IN PATIENTS WITH ADVANCED RENAL CELL CANCER

Study identification

NCT ID
NCT02133742
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Pfizer
Industry
Enrollment
52 participants

Conditions and interventions

Interventions

  • Axitinib Drug
  • MK-3475 Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 15, 2014
Primary completion
Mar 30, 2017
Completion
Jul 2, 2019
Last update posted
Jul 27, 2021

2014 – 2019

United States locations

U.S. sites
19
U.S. states
9
U.S. cities
10
Facility City State ZIP Site status
Georgetown University Medical Center Washington D.C. District of Columbia 20007
H. Lee Moffitt Cancer Center & Research Institute, Inc. Tampa Florida 33612
Massachusetts General Hospital Boston Massachusetts 02114
Brigham & Women's Hospital Boston Massachusetts 02115
Beth Israel Deaconess Medical Center Boston Massachusetts 02215
Dana-Farber Cancer Institute Boston Massachusetts 02215
Karmanos Cancer Institute Detroit Michigan 48201
Roswell Park Cancer Institute Buffalo New York 14263
Attn. Alicia Sammarco, RPh, NYU Investigational Pharmacy New York New York 10016
NYU Langone Medical Center New York New York 10016
NYU Langone New York New York 10016
Investigational Drug Services Columbus Ohio 43210
James Cancer Hospital Columbus Ohio 43210
The Ohio State University Brain and Spine Hospital Columbus Ohio 43210
Martha Morehouse Medical Plaza Columbus Ohio 43221
Fox Chase Cancer Center Philadelphia Pennsylvania 19111
Henry-Joyce Cancer Clinic Nashville Tennessee 37232
Vanderbilt Oncology Pharmacy Nashville Tennessee 37232
Texas Oncology - Baylor Charles A. Sammons Cancer Center Dallas Texas 75246

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02133742, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 27, 2021 · Synced May 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02133742 live on ClinicalTrials.gov.

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