ClinicalTrials.gov record
S1222 Trial (Everolimus, Anastrozole and Fulvestrant) in Post-Menopausal Stage IV Breast Cancer
ClinicalTrials.gov ID: NCT02137837
Public ClinicalTrials.gov record NCT02137837. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Fulvestrant Alone Versus Fulvestrant and Everolimus Versus Fulvestrant, Everolimus and Anastrozole: A Phase III Randomized Placebo-Controlled Trial in Postmenopausal Patients
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This randomized Phase III trial studies how well the combination of fulvestrant and everolimus together or the combination of anastrozole, fulvestrant and everolimus together, improve progression-free survival (PFS) versus fulvestrant alone.
Study identification
- NCT ID
- NCT02137837
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 37 participants
Conditions and interventions
Conditions
Interventions
- Fulvestrant Drug
- Anastrozole Drug
- Everolimus Drug
- Placebo - Anastrozole Drug
- Placebo - Everolimus Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 2014 (Type not available)
- Primary completion
- Dec 31, 2019 (Actual)
- Completion
- Dec 31, 2019 (Actual)
- Last update posted
- Jan 28, 2021
2014 – 2019
United States locations
- U.S. sites
- 223
- U.S. states
- 30
- U.S. cities
- 153
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alaska Breast Care and Surgery LLC | Anchorage | Alaska | 99508 | — |
| Alaska Women's Cancer Care | Anchorage | Alaska | 99508 | — |
| Anchorage Oncology Centre | Anchorage | Alaska | 99508 | — |
| Katmai Oncology Group | Anchorage | Alaska | 99508 | — |
| Providence Alaska Medical Center | Anchorage | Alaska | 99508 | — |
| Virginia G. Piper Cancer Center | Scottsdale | Arizona | 85258 | — |
| University of Arizona Cancer Center - Orange Grove | Tucson | Arizona | 85704 | — |
| University of Arizona Cancer Center - North Campus | Tucson | Arizona | 85719 | — |
| Southern Arizona VA Health Care System | Tucson | Arizona | 85723 | — |
| University of Arizona Medical Center - Univ Campus | Tucson | Arizona | 85724 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Providence St. Joseph Medical Ctr/Disney Family CC | Burbank | California | 91505 | — |
| City of Hope-Corona | Corona | California | 92879 | — |
| City of Hope National Medical Center | Duarte | California | 91010 | — |
| City of Hope Antelope Valley | Lancaster | California | 93534 | — |
| Bay Area Tumor Institute | Oakland | California | 94609 | — |
| Summit Medical Center | Oakland | California | 94609 | — |
| Epic Care - Oakland | Oakland | California | 94612 | — |
| City of Hope South Pasadena | South Pasadena | California | 91030 | — |
| Bridgeport Hospital | Bridgeport | Connecticut | 06610 | — |
| St. Francis Hospital and Medical Center | Hartford | Connecticut | 06105 | — |
| Yale University | New Haven | Connecticut | 06520 | — |
| Yale-New Haven Hospital North Haven Medical Center | North Haven | Connecticut | 06473 | — |
| Sacred Heart Hospital | Pensacola | Florida | 32504 | — |
| Cleveland Clinic - Weston | Weston | Florida | 33331 | — |
| South Georgia Medical Center - Pearlman Cancer Ctr | Valdosta | Georgia | 31602 | — |
| Oncare Hawaii Inc-POB I | Honolulu | Hawaii | 96813 | — |
| Oncare Hawaii, Inc - POB II | Honolulu | Hawaii | 96813 | — |
| Straub Clinic and Hospital | Honolulu | Hawaii | 96813 | — |
| University of Hawaii Cancer Center | Honolulu | Hawaii | 96813 | — |
| Oncare Hawaii, Inc - Kuakini | Honolulu | Hawaii | 96817 | — |
| Oncare Hawaii, Inc - Liliha | Honolulu | Hawaii | 96817 | — |
| Kapiolani Medical Center for Women and Children | Honolulu | Hawaii | 96826 | — |
| Wilcox Memorial Hospital and Kauai Medical Clinic | Lihue | Hawaii | 96766 | — |
| Oncare Hawaii, Inc - Pali Momi | ‘Aiea | Hawaii | 96701 | — |
| Pali Momi Medical Center | ‘Aiea | Hawaii | 96701 | — |
| St. Alphonsus Regional Medical Center | Boise | Idaho | 83706 | — |
| Kootenai Medical Center | Coeur d'Alene | Idaho | 83814 | — |
| Kootenai Cancer Center | Post Falls | Idaho | 83854 | — |
| Kootenai Cancer Clinic | Sandpoint | Idaho | 83864 | — |
| Centralia Oncology Clinic | Centralia | Illinois | 62801 | — |
| Cancer Care Specialists of Central Illinois | Decatur | Illinois | 62526 | — |
| Decatur Memorial Hospital | Decatur | Illinois | 62526 | — |
| Heartland Cancer Research NCORP | Decatur | Illinois | 62526 | — |
| Kishwaukee Community Hospital | DeKalb | Illinois | 60115 | — |
| Crossroads Cancer Center | Effingham | Illinois | 62401 | — |
| Loyola University Stritch School of Medicine | Maywood | Illinois | 60153 | — |
| Marjorie Weinberg Cancer Center | Melrose Park | Illinois | 60160 | — |
| Good Samaritan Regional Health Center | Mount Vernon | Illinois | 62864 | — |
| Central Illinois Hematology Oncology Center | Springfield | Illinois | 62702 | — |
| Springfield Clinic | Springfield | Illinois | 62703 | — |
| Memorial Medical Center | Springfield | Illinois | 62781 | — |
| Cancer Care Specialists of Illinois-Swansea | Swansea | Illinois | 62226 | — |
| Reid Hospital and Health Care Services | Richmond | Indiana | 47374 | — |
| Cancer Center of Kansas - Chanute | Chanute | Kansas | 66720 | — |
| Cancer Center of Kansas - Dodge City | Dodge City | Kansas | 67801 | — |
| Cancer Center of Kansas - El Dorado | El Dorado | Kansas | 67042 | — |
| Cancer Center of Kansas - Fort Scott | Fort Scott | Kansas | 66701 | — |
| Cancer Center of Kansas - Independence | Independence | Kansas | 67301 | — |
| Cancer Center of Kansas - Kingman | Kingman | Kansas | 67068 | — |
| Lawrence Memorial Hospital | Lawrence | Kansas | 66044 | — |
| Cancer Center of Kansas - Liberal | Liberal | Kansas | 67901 | — |
| Cancer Center of Kansas - Newton | Newton | Kansas | 67114 | — |
| Cancer Center of Kansas - Parsons | Parsons | Kansas | 67357 | — |
| Cancer Center of Kansas - Pratt | Pratt | Kansas | 67124 | — |
| Cancer Center of Kansas - Salina | Salina | Kansas | 67401 | — |
| Cancer Center of Kansas - Wellington | Wellington | Kansas | 67152 | — |
| Associates in Women's Health | Wichita | Kansas | 67208 | — |
| Cancer Center of Kansas - Medical Arts Tower | Wichita | Kansas | 67208 | — |
| Cancer Center of Kansas - Wichita | Wichita | Kansas | 67214 | — |
| Via Christi Regional Medical Center | Wichita | Kansas | 67214 | — |
| Wichita NCI Community Oncology Research Program | Wichita | Kansas | 67214 | — |
| Cancer Center of Kansas - Winfield | Winfield | Kansas | 67156 | — |
| De Soto Regional Medical Center | Mansfield | Louisiana | 71052 | — |
| University Health Conway | Monroe | Louisiana | 71210 | — |
| Highland Clinic | Shreveport | Louisiana | 71105 | — |
| Louisiana State University Health Sciences Center | Shreveport | Louisiana | 71130 | — |
| Sinai Hospital of Baltimore | Baltimore | Maryland | 21215 | — |
| Beverly Hospital | Beverly | Massachusetts | 01915 | — |
| Lahey Hospital and Medical Center | Burlington | Massachusetts | 01805 | — |
| Addison Gilbert Hospital | Gloucester | Massachusetts | 01930 | — |
| Winchester Hospital | Winchester | Massachusetts | 01890 | — |
| Michigan Cancer Research Consortium NCORP | Ann Arbor | Michigan | 48106 | — |
| St. Joseph Mercy Hospital | Ann Arbor | Michigan | 48106 | — |
| University of Michigan Medical Center | Ann Arbor | Michigan | 48109 | — |
| Oakwood Healthcare, Inc. | Dearborn | Michigan | 48123 | — |
| Wayne State University Medical Center | Detroit | Michigan | 48202 | — |
| St. John Hospital and Medical Center | Detroit | Michigan | 48236 | — |
| Genesys Hurley Cancer Institute | Flint | Michigan | 48503 | — |
| Hurley Medical Center | Flint | Michigan | 48503 | — |
| William Beaumont Hospital-Grosse Pointe | Grosse Pointe | Michigan | 48230 | — |
| Allegiance Health | Jackson | Michigan | 49201 | — |
| Sparrow Health System | Lansing | Michigan | 48909 | — |
| St. Mary Mercy Hospital | Livonia | Michigan | 48154 | — |
| MidMichigan Medical Center - Midland | Midland | Michigan | 48670 | — |
| St Joseph Mercy Hospital - Oakland | Pontiac | Michigan | 48341 | — |
| St. Joseph Mercy Port Huron | Port Huron | Michigan | 48060 | — |
| Beaumont Children's Hospital-Royal Oak | Royal Oak | Michigan | 48073 | — |
| Beaumont NCI Community Oncology Research Program | Royal Oak | Michigan | 48073 | — |
| St. Mary's Health System | Saginaw | Michigan | 48601 | — |
| Beaumont Hospital, Troy Campus | Troy | Michigan | 48085 | — |
| St. John Macomb Hospital | Warren | Michigan | 48093 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | — |
| Central Care Cancer Ctr-Carrie J. Babb Cancer Ctr | Bolivar | Missouri | 65613 | — |
| Cox Cancer Center Branson | Branson | Missouri | 65616 | — |
| St. Francis Medical Center | Cape Girardeau | Missouri | 63701 | — |
| Mercy Hospital - Joplin | Joplin | Missouri | 64804 | — |
| Mercy Clinic Care and Hematology - Rolla | Rolla | Missouri | 65401 | — |
| PCRMC Bond Clinic | Rolla | Missouri | 65401 | — |
| Phelps County Regional Medical Center | Rolla | Missouri | 65401 | — |
| Cancer Research for the Ozarks NCORP | Springfield | Missouri | 65804 | — |
| Mercy Hospital Springfield | Springfield | Missouri | 65804 | — |
| CoxHealth South Hospital | Springfield | Missouri | 65807 | — |
| St. Louis Cancer and Breast Institute-South City | St Louis | Missouri | 63109 | — |
| Christian Hospital | St Louis | Missouri | 63136 | — |
| Mercy Hospital St. Louis | St Louis | Missouri | 63141 | — |
| Mercy Hospital Washington | Washington | Missouri | 63090 | — |
| Montana Cancer Consortium NCORP | Billings | Montana | 59101 | — |
| Billings Clinic Cancer Center | Billings | Montana | 59107 | — |
| Bozeman Deaconess Hospital | Bozeman | Montana | 59715 | — |
| St. James Community Hosp and Cancer Treatment Center | Butte | Montana | 59702 | — |
| Benefis Healthcare West Campus | Great Falls | Montana | 59405 | — |
| St. Peter's Community Hospital | Helena | Montana | 59601 | — |
| Kalispell Regional Medical Center | Kalispell | Montana | 59901 | — |
| Community Medical Center | Missoula | Montana | 59801 | — |
| St. Patrick Hospital | Missoula | Montana | 59806 | — |
| CHI Health Good Samaritan Hospital | Kearney | Nebraska | 68847 | — |
| Southeastern Medical Oncology Center-Clinton | Clinton | North Carolina | 28328 | — |
| Southeastern Medical Oncology Center-Goldsboro | Goldsboro | North Carolina | 27534 | — |
| Wayne Memorial Hospital | Goldsboro | North Carolina | 27534 | — |
| Hendersonville Hematology and Oncology at Pardee | Hendersonville | North Carolina | 28739 | — |
| Margaret R. Pardee Memorial Hospital | Hendersonville | North Carolina | 28791 | — |
| Park Ridge Health | Hendersonville | North Carolina | 28792 | — |
| Southeastern Medical Oncology Center-Jacksonville | Jacksonville | North Carolina | 28546 | — |
| Southeastern Medical Oncology Center-Wilson | Wilson | North Carolina | 27893 | — |
| Wilson Medical Center | Wilson | North Carolina | 27893 | — |
| Cleveland Clinic Cancer Center - Beachwood | Beachwood | Ohio | 44122 | — |
| Strecker Cancer Center-Belpre | Belpre | Ohio | 45714 | — |
| Adena Regional Medical Center | Chillicothe | Ohio | 45601 | — |
| VA Medical Center - Cincinnati | Cincinnati | Ohio | 45220 | — |
| University of Cincinnati Medical Center | Cincinnati | Ohio | 45267 | — |
| Cleveland Clinic Cancer Center - Fairview Hospital | Cleveland | Ohio | 44111 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Mount Carmel East Hospital | Columbus | Ohio | 43213 | — |
| Columbus NCI Community Oncology Research Program | Columbus | Ohio | 43215 | — |
| The Mark H. Zangmeister Center | Columbus | Ohio | 43219 | — |
| Mount Carmel Health Center West | Columbus | Ohio | 43222 | — |
| Good Samaritan Hospital and Health Center | Dayton | Ohio | 45406 | — |
| Samaritan North Health Center | Dayton | Ohio | 45415 | — |
| Dayton NCI Community Oncology Research Program | Dayton | Ohio | 45420 | — |
| VA Medical Center - Dayton | Dayton | Ohio | 45428 | — |
| Wayne Hospital | Greenville | Ohio | 45331 | — |
| Cleveland Clinic Cancer Center - Independence | Independence | Ohio | 44131 | — |
| Kettering Medical Center | Kettering | Ohio | 45429 | — |
| Fairfield Medical Center | Lancaster | Ohio | 43130 | — |
| Cleveland Clinic Cancer Center - Mansfield | Mansfield | Ohio | 44906 | — |
| Marietta Memorial Hospital | Marietta | Ohio | 45750 | — |
| Hillcrest Hospital Cancer Center | Mayfield Heights | Ohio | 44124 | — |
| Knox Community Hospital | Mount Vernon | Ohio | 43050 | — |
| Licking Memorial Hospital | Newark | Ohio | 43055 | — |
| Southern Ohio Medical Center | Portsmouth | Ohio | 45662 | — |
| North Coast Cancer Care, Inc. | Sandusky | Ohio | 44870 | — |
| Springfield Regional Medical Center | Springfield | Ohio | 45501 | — |
| Springfield Regional Cancer Center | Springfield | Ohio | 45504 | — |
| Cleveland Clinic Strongsville Family Health Center | Strongsville | Ohio | 44136 | — |
| Upper Valley Medical Centers | Troy | Ohio | 45373 | — |
| South Pointe Hospital | Warrensville Heights | Ohio | 44122 | — |
| St. Ann's Hospital | Westerville | Ohio | 43081 | — |
| Cleveland Clinic Cancer Center - Wooster | Wooster | Ohio | 44691 | — |
| Genesis Healthcare System Cancer Care Center | Zanesville | Ohio | 43701 | — |
| St. Charles Health System | Bend | Oregon | 97701 | — |
| Clackamas Radiation Oncology Center | Clackamas | Oregon | 97015 | — |
| Providence Oncology and Hematology Care Southeast | Clackamas | Oregon | 97015 | — |
| Providence Newberg Medical Center | Newberg | Oregon | 97132 | — |
| Providence Willamette Falls Medical Center | Oregon City | Oregon | 97045 | — |
| Providence Portland Medical Center | Portland | Oregon | 97213 | — |
| Providence St. Vincent Medical Center | Portland | Oregon | 97225 | — |
| McLeod Regional Medical Center | Florence | South Carolina | 29501 | — |
| Gibbs Cancer Center-Gaffney | Gaffney | South Carolina | 29341 | — |
| Gibbs Cancer Center-Pelham | Greer | South Carolina | 29651 | — |
| Spartanburg Medical Cancer | Spartanburg | South Carolina | 29303 | — |
| MGC Hematology Oncology-Union | Union | South Carolina | 29379 | — |
| Wellmont Bristol Regional Medical Center | Bristol | Tennessee | 37620 | — |
| Wellmont Medical Associates Oncology and Hematology | Bristol | Tennessee | 37620 | — |
| Wellmont Medical Assoc Onc and Hem-Johnson City | Johnson City | Tennessee | 37604 | — |
| Holston Valley Hospital and Medical Center | Kingsport | Tennessee | 37660 | — |
| Wellmont Medical Assoc Onc and Hem-Kingsport | Kingsport | Tennessee | 37660 | — |
| Thompson Cancer Survival Center | Knoxville | Tennessee | 37916 | — |
| Don and Sybil Harrington Cancer Center | Amarillo | Texas | 79106 | — |
| University of Utah Medical Center | Salt Lake City | Utah | 84132 | — |
| Southwest Virginia Cancer Center | Norton | Virginia | 24273 | — |
| Island Hospital | Anacortes | Washington | 98221 | — |
| Auburn Regional Medical Center | Auburn | Washington | 98001 | — |
| Virginia Mason Bainbridge Island Medical Center | Bainbridge Island | Washington | 98110 | — |
| Overlake Hospital Medical Center | Bellevue | Washington | 98004 | — |
| Swedish Cancer Inst-Eastside Oncology Hematoly | Bellevue | Washington | 98005 | — |
| PeaceHealth St. Joseph Medical Center | Bellingham | Washington | 98225 | — |
| Swedish Medical Center - Edmonds | Edmonds | Washington | 98026 | — |
| Virginia Mason Federal Way Medical Center | Federal Way | Washington | 98002 | — |
| Tacoma/Valley Radiation Oncology Ctrs-Gig Harbor | Gig Harbor | Washington | 98332 | — |
| MultiCare Gig Harbor Medical Park | Gig Harbor | Washington | 98335 | — |
| Swedish Cancer Institute-Issaquah | Issaquah | Washington | 98029 | — |
| PeaceHealth St. John Medical Center | Longview | Washington | 98632 | — |
| Virginia Mason Lynnwood Medical Center | Lynnwood | Washington | 98036 | — |
| MultiCare Good Samaritan Hospital | Puyallup | Washington | 98372 | — |
| Tacoma/Valley Radiation Oncology Ctrs-Puyallup | Puyallup | Washington | 98372 | — |
| Virginia Mason Medical Center | Seattle | Washington | 98101 | — |
| Minor and James Medical, PLLC | Seattle | Washington | 98104 | — |
| Pacific Cancer Research Consortium NCORP | Seattle | Washington | 98104 | — |
| Pacific Medical Center - First Hill | Seattle | Washington | 98104 | — |
| Swedish Medical Center | Seattle | Washington | 98104 | — |
| Swedish Medical Center - Ballard Campus | Seattle | Washington | 98107 | — |
| Fred Hutchinson Cancer Research Center | Seattle | Washington | 98109 | — |
| Group Health Cooperative-Seattle | Seattle | Washington | 98112 | — |
| Tacoma/Valley Radiation Oncology Ctrs-Jackson Hill | Tacoma | Washington | 97405 | — |
| Mary Bridge Children's Hospital and Health Center | Tacoma | Washington | 98405 | — |
| MultiCare Tacoma General Hospital | Tacoma | Washington | 98405 | — |
| Northwest NCI Community Oncology Research Program | Tacoma | Washington | 98405 | — |
| Tacoma/Valley Radiation Oncology Ctrs-Saint Joe's | Tacoma | Washington | 98405 | — |
| Multicare Health System | Tacoma | Washington | 98415 | — |
| PeaceHealth Southwest Medical Center | Vancouver | Washington | 98668 | — |
| Billings Clinic-Cody | Cody | Wyoming | 82414 | — |
| Welch Cancer Center - Sheridan Memorial Hospital | Sheridan | Wyoming | 82801 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02137837, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 28, 2021 · Synced Oct 26, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02137837 live on ClinicalTrials.gov.