ClinicalTrials.gov record
A Long-Term Safety Study of ALKS 5461
ClinicalTrials.gov ID: NCT02141399
Public ClinicalTrials.gov record NCT02141399. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Multicenter Study of the Long-Term Safety and Tolerability of ALKS 5461 for the Adjunctive Treatment of Major Depressive Disorder in Adults Who Have an Inadequate Response to Antidepressant Therapy (the FORWARD-2 Study)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a 52-week open-label study to evaluate the safety and tolerability of ALKS 5461.
Study identification
- NCT ID
- NCT02141399
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,485 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 2014 (Actual)
- Primary completion
- Nov 20, 2017 (Actual)
- Completion
- Nov 20, 2017 (Actual)
- Last update posted
- Dec 14, 2018
2014 – 2017
United States locations
- U.S. sites
- 123
- U.S. states
- 31
- U.S. cities
- 108
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alkermes Investigational Site | Birmingham | Alabama | 35226 | — |
| Alkermes Investigational Site | Birmingham | Alabama | 35294 | — |
| Alkermes Investigational Site | Tucson | Arizona | 85712 | — |
| Alkermes Investigational Site | Little Rock | Arkansas | 72211 | — |
| Alkermes Investigational Site | Bellflower | California | 90706 | — |
| Alkermes Investigational Site | Beverly Hills | California | 90210 | — |
| Alkermes Investigational Site | Carson | California | 90746 | — |
| Alkermes Investigational Site | Garden Grove | California | 92845 | — |
| Alkermes Investigational Site | Glendale | California | 91206 | — |
| Alkermes Investigational Site | Los Alamitos | California | 90720 | — |
| Alkermes Investigational Site | Los Angeles | California | 90024 | — |
| Alkermes Investigational Site | National City | California | 91950 | — |
| Alkermes Investigational Site | Oakland | California | 94612 | — |
| Alkermes Investigational Site | Oceanside | California | 92056 | — |
| Alkermes Investigational Site | Orange | California | 92868 | — |
| Alkermes Investigational Site | Pico Rivera | California | 90660 | — |
| Alkermes Investigational Site | Redlands | California | 92374 | — |
| Alkermes Investigational Site | San Gabriel | California | 91776 | — |
| Alkermes Investigational Site | Sherman Oaks | California | 91403 | — |
| Alkermes Investigational Site | Temecula | California | 92591 | — |
| Alkermes Investigational Site | Torrance | California | 90502 | — |
| Alkermes Investigational Site | Upland | California | 91786 | — |
| Alkermes Investigational Site | Colorado Springs | Colorado | 80910 | — |
| Alkermes Investigational Site | Denver | Colorado | 80209 | — |
| Alkermes Investigational Site | Hartford | Connecticut | 06106 | — |
| Alkermes Investigational Site | Norwich | Connecticut | 06360 | — |
| Alkermes Investigational Site | Bradenton | Florida | 34201 | — |
| Alkermes Investigational Site | Coral Springs | Florida | 33067 | — |
| Alkermes Investigational Site | Fort Myers | Florida | 33912 | — |
| Alkermes Investigational Site | Gainesville | Florida | 32607 | — |
| Alkermes Investigational Site | Hallandale | Florida | 33009 | — |
| Alkermes Investigational Site | Hialeah | Florida | 33016 | — |
| Alkermes Investigational Site | Jacksonville | Florida | 32256 | — |
| Alkermes Investigational Site | Lauderhill | Florida | 33319 | — |
| Alkermes Investigational Site | Maitland | Florida | 32751 | — |
| Alkermes Investigational Site | Melbourne | Florida | 32901 | — |
| Alkermes Investigational Site | North Miami | Florida | 33161 | — |
| Alkermes Investigational Site | Oakland Park | Florida | 33334 | — |
| Alkermes Investigational Site | Orlando | Florida | 32801 | — |
| Alkermes Investigational Site | Tampa | Florida | 33613 | — |
| Alkermes Investigational Site | The Villages | Florida | 32162 | — |
| Alkermes Investigational Site | West Palm Beach | Florida | 33407 | — |
| Alkermes Investigational Site | Winter Haven | Florida | 33880 | — |
| Alkermes Investigational Site | Alpharetta | Georgia | 30005 | — |
| Alkermes Investigational Site | Atlanta | Georgia | 30308 | — |
| Alkermes Investigational Site | Decatur | Georgia | 30030 | — |
| Alkermes Investigational Site | Smyrna | Georgia | 30080 | — |
| Alkermes Investigational Site | Chicago | Illinois | 60634 | — |
| Alkermes Investigational Site | Chicago | Illinois | 60640 | — |
| Alkermes Investigational Site | Deerfield | Illinois | 60015 | — |
| Alkermes Investigational Site | Hoffman Estates | Illinois | 60169 | — |
| Alkermes Investigational Site | Joliet | Illinois | 60435 | — |
| Alkermes Investigational Site | Oak Brook | Illinois | 60523 | — |
| Alkermes Investigational Site | Skokie | Illinois | 60076 | — |
| Alkermes Investigational Site | Indianapolis | Indiana | 46260 | — |
| Alkermes Investigational Site | Lafayette | Indiana | 47905 | — |
| Alkermes Investigational Site | Newburgh | Indiana | 47630 | — |
| Alkermes Investigational Site | Valparaiso | Indiana | 46383 | — |
| Alkermes Investigational Site | Edgewood | Kentucky | 41017 | — |
| Alkermes Investigational Site | Owensboro | Kentucky | 42301 | — |
| Alkermes Investigational Site | Baltimore | Maryland | 21204 | — |
| Alkermes Investigational Site | Baltimore | Maryland | 21208 | — |
| Alkermes Investigational Site | Washington D.C. | Maryland | 20016 | — |
| Alkermes Investigational Site | Belmont | Massachusetts | 02478 | — |
| Alkermes Investigational Site | Brockton | Massachusetts | 02301 | — |
| Alkermes Investigational Site | Watertown | Massachusetts | 02472 | — |
| Alkermes Investigational Site | Worcester | Massachusetts | 01655 | — |
| Alkermes Investigational Site | Flowood | Mississippi | 39232 | — |
| Alkermes Investigational Site | O'Fallon | Missouri | 63368 | — |
| Alkermes Investigational Site | Saint Charles | Missouri | 63304 | — |
| Alkermes Investigational Site | St Louis | Missouri | 63109 | — |
| Alkermes Investigational Site | St Louis | Missouri | 63141 | — |
| Alkermes Investigational Site | Berlin | New Jersey | 80091 | — |
| Alkermes Investigational Site | Cherry Hill | New Jersey | 08002 | — |
| Alkermes Investigational Site | Princeton | New Jersey | 08540 | — |
| Alkermes Investigational Site | Albuquerque | New Mexico | 87109 | — |
| Alkermes Investigational Site | Brooklyn | New York | 11241 | — |
| Alkermes Investigational Site | Jamaica | New York | 11432 | — |
| Alkermes Investigational Site | Mount Kisco | New York | 10549 | — |
| Alkermes Investigational Site | New York | New York | 10019 | — |
| Alkermes Investigational Site | New York | New York | 10023 | — |
| Alkermes Investigational Site | New York | New York | 10029 | — |
| Alkermes Investigational Site | New York | New York | 10128 | — |
| Alkermes Investigational Site | New York | New York | 10168 | — |
| Alkermes Investigational Site | Staten Island | New York | 10305 | — |
| Alkermes Investigational Site | Staten Island | New York | 10312 | — |
| Alkermes Investigational Site | Charlotte | North Carolina | 28204 | — |
| Alkermes Investigational Site | High Point | North Carolina | 27265 | — |
| Alkermes Investigational Site | Beachwood | Ohio | 44122 | — |
| Alkermes Investigational Site | Canton | Ohio | 44718 | — |
| Alkermes Investigational Site | Cincinnati | Ohio | 45215 | — |
| Alkermes Investigational Site | Cincinnati | Ohio | 45227 | — |
| Alkermes Investigational Site | Dayton | Ohio | 45417 | — |
| Alkermes Investigational Site | Mason | Ohio | 45040 | — |
| Alkermes Investigational Site | Middleburg Heights | Ohio | 44130 | — |
| Alkermes Investigational Site | Oklahoma City | Oklahoma | 73103 | — |
| Alkermes Investigational Site | Oklahoma City | Oklahoma | 73112 | — |
| Alkermes Investigational Site | Portland | Oregon | 97210 | — |
| Alkermes Investigational Site | Portland | Oregon | 97214 | — |
| Alkermes Investigational Site | Salem | Oregon | 97301 | — |
| Alkermes Investigational Site | Allentown | Pennsylvania | 18104 | — |
| Alkermes Investigational Site | Media | Pennsylvania | 19063 | — |
| Alkermes Investigational Site | Philadelphia | Pennsylvania | 19104 | — |
| Alkermes Investigational Site | Philadelphia | Pennsylvania | 19107 | — |
| Alkermes Investigational Site | Lincoln | Rhode Island | 02865 | — |
| Alkermes Investigational Site | Charleston | South Carolina | 29407 | — |
| Alkermes Investigational Site | Memphis | Tennessee | 38119 | — |
| Alkermes Investigational Site | Austin | Texas | 78731 | — |
| Alkermes Investigational Site | Dallas | Texas | 75231 | — |
| Alkermes Investigational Site | Dallas | Texas | 75390 | — |
| Alkermes Investigational Site | DeSoto | Texas | 75115 | — |
| Alkermes Investigational Site | Houston | Texas | 77081 | — |
| Alkermes Investigational Site | Houston | Texas | 77098 | — |
| Alkermes Investigational Site | San Antonio | Texas | 78229 | — |
| Alkermes Investigational Site | Sugar Land | Texas | 77478 | — |
| Alkermes Investigational Site | Wichita Falls | Texas | 76309 | — |
| Alkermes Investigational Site | Clinton | Utah | 84015 | — |
| Alkermes Investigational Site | Woodstock | Vermont | 05091 | — |
| Alkermes Investigational Site | Bellevue | Washington | 98007 | — |
| Alkermes Investigational Site | Seattle | Washington | 98104 | — |
| Alkermes Investigational Site | Spokane | Washington | 99204 | — |
| Alkermes Investigational Site | Middleton | Wisconsin | 53562 | — |
| Alkermes Investigational Site | Waukesha | Wisconsin | 53188 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 35 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02141399, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 14, 2018 · Synced Sep 30, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02141399 live on ClinicalTrials.gov.