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Completed Phase 2Phase 3 Interventional Results available

Open Label Extension Study of Nalbuphine HCl ER in Hemodialysis Patients With Uremic Pruritus

ClinicalTrials.gov ID: NCT02143973

Public ClinicalTrials.gov record NCT02143973. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 6:57 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open Label Extension Study of the Safety and Anti-Pruritic Efficacy of Nalbuphine HCl ER Tablets in Hemodialysis Patients With Uremic Pruritus

Study identification

NCT ID
NCT02143973
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2, Phase 3
Lead sponsor
Trevi Therapeutics
Industry
Enrollment
167 participants

Conditions and interventions

Interventions

  • nalbuphine HCl ER Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 31, 2014
Primary completion
Dec 31, 2015
Completion
Dec 31, 2015
Last update posted
May 20, 2025

2014 – 2016

United States locations

U.S. sites
35
U.S. states
22
U.S. cities
32
Facility City State ZIP Site status
Nephrology Associates PC Birmingham Alabama 35211
University South Alabama Medical Center Mobile Alabama 36617
Arizona Kidney Disease and Hypertension Center Phoenix Arizona 85012
U.S. Renal Care Inc. Pine Bluff Arkansas 71603
North America Research Institute Azusa California 91702
Pegasus Dialysis Center Bakersfield California 93308
Central Nephrology Medical Group Bakersfield California 93309
Mark Lee MD, Inc Whittier California 90606
Nephrology and Hypertension Associates PC Middlebury Connecticut 06762
Pines Clinical Research Pembroke Pines Florida 33025
Genesis Clinical Research Tampa Florida 33614
DaVita Central Orlando Dialysis Winter Park Florida 32789
Southwest Georgia Nephrology Clinic PC Albany Georgia 31701
Renal Physicians of Georgia Macon Georgia 31217
Pacific Renal Research Institute Meridian Idaho 83642
Fresenius Medical Care of Evergreen Park Evergreen Park Illinois 60805
Western New England Renal and Transplant Association Springfield Massachusetts 01107
Nephrology Center DBA Paragon Health Kalamazoo Michigan 49007
McComb Limited Care Facility McComb Mississippi 39648
Kidney Associates of Kansas City PC Kansas City Missouri 64131
Nephrology-Hypertension Associates of Central New Jersey PA North Brunswick New Jersey 80902
Renal Medicine Associates Albuquerque New Mexico 87109
Newtown Dialysis Center Inc Astoria New York 11102
Durham Nephrology Associates Durham North Carolina 27704
Wake Nephrology Associates PA Raleigh North Carolina 27609
Brookview Hills Research Associates LLC Winston-Salem North Carolina 27103
University of Cincinnati Cincinnati Ohio 45267
Nephrology Research Consortium Bethlehem Pennsylvania 18017
Delaware Valley Nephrology Philadelphia Pennsylvania 19118
Dialysis Clinic, Inc. Philadelphia Pennsylvania 19140
Carolina Diabetes and Kidney Center Sumter South Carolina 29150
SouthEast Renal Research Institute Chattanooga Tennessee 37408
U.S. Renal Care, Inc. Fort Worth Texas 76105
U.S. Renal Care Inc. Fort Worth Texas 76164
U.S. Renal Care Inc Mansfield Texas 76063

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02143973, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 20, 2025 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02143973 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →