Multicenter Study of Rociletinib Administered to Patients With Previously Treated Mutant EGFR Non-small Cell Lung Cancer
Public ClinicalTrials.gov record NCT02147990. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
TIGER-2: A Phase 2, Open-label, Multicenter, Safety and Efficacy Study of Oral CO-1686 as 2nd Line EGFR-directed TKI in Patients With Mutant EGFR Non-small Cell Lung Cancer (NSCLC)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the safety and anti-tumor effect of rociletinib. The trial is open-ended, which means patients will continue to take rociletinib until the study doctor determines it is no longer beneficial for them.
Study identification
- NCT ID
- NCT02147990
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 318 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 16, 2014 (Actual)
- Primary completion
- Jul 30, 2019 (Actual)
- Completion
- Aug 27, 2019 (Actual)
- Last update posted
- Aug 12, 2020
2014 – 2019
United States locations
- U.S. sites
- 41
- U.S. states
- 15
- U.S. cities
- 39
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UCLA Medical Center | Alhambra | California | 91801 | — |
| Comprehensive Blood and Cancer Center | Bakersfield | California | 93309 | — |
| Saint Jude Heritage Healthcare | Fullerton | California | 92835 | — |
| University of California San Diego Moores Cancer Center | La Jolla | California | 92093 | — |
| Northridge Hospital Medical Center | Northridge | California | 91328 | — |
| Cancer Care Associates | Redondo Beach | California | 90277 | — |
| University of California Davis Medical Center | Sacramento | California | 95817 | — |
| University of California San Francisco | San Francisco | California | 94115 | — |
| Coastal Integrative Cancer Care | San Luis Obispo | California | 93401 | — |
| Saint Mary's Regional Cancer Center | Grand Junction | Colorado | 81501-6132 | — |
| Rocky Mountain Cancer Centers, LLP | Lone Tree | Colorado | 80218 | — |
| Yale University School of Medicine | New Haven | Connecticut | 32135 | — |
| Advanced Medical Specialties | Miami | Florida | 33176 | — |
| Cleveland Clinic Florida | Weston | Florida | 33331 | — |
| Northwestern University Feinberg School of Medicine | Chicago | Illinois | 60611 | — |
| University of Illinois Chicago | Chicago | Illinois | 60612 | — |
| Illinois Cancer Specialists | Niles | Illinois | 60714 | — |
| Beth Israel Comprehensive Cancer Center | Boston | Massachusetts | 02215 | — |
| Lahey Hospital and Medical Center | Burlington | Massachusetts | 01805 | — |
| Minnesota Oncology Hematology, P.A | Minneapolis | Minnesota | 55404 | — |
| Mayo Clinic - Rochester | Rochester | Minnesota | 55905 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| New York Oncology Hematology, PC | Latham | New York | 12110-2188 | — |
| University of Rochester | Rochester | New York | 14642 | — |
| Montefiore Medical Center | The Bronx | New York | 10461 | — |
| University Hospitals of Cleveland | Cleveland | Ohio | 44106 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| Tennessee Oncology, PLLC | Nashville | Tennessee | 37203 | — |
| Texas Oncology P.A. | Amarillo | Texas | 79106 | — |
| USO - Texas Oncology P.A. | Arlington | Texas | 76014 | — |
| Texas Oncology-Austin Central | Austin | Texas | 78705 | — |
| Texas Oncology-Beaumont | Beaumont | Texas | 77702 | — |
| Texas Oncology P.A. | Bedford | Texas | 76022 | — |
| Texas Oncology P.A. | Dallas | Texas | 75246 | — |
| Texas Oncology P.A. | Flower Mound | Texas | 75028 | — |
| The Methodist Hospital | Houston | Texas | 77030 | — |
| Texas Oncology - Plano East | Plano | Texas | 75075-7787 | — |
| Virginia Cancer Specialists | Fairfax | Virginia | 22031 | — |
| Northwest Cancer Specialists, P.C. | Vancouver | Washington | 98686 | — |
| Yakima Valley Memorial Hospital, North Star Lodge | Yakima | Washington | 98902 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 50 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02147990, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 12, 2020 · Synced Oct 18, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02147990 live on ClinicalTrials.gov.