Efficacy, Safety, and Tolerability Study of AVP-786 as an Adjunctive Therapy in Patients With Major Depressive Disorder With an Inadequate Response to Antidepressant Treatment
Public ClinicalTrials.gov record NCT02153502. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Assess the Efficacy, Safety, and Tolerability of AVP-786 (Deuterium Modified Dextromethorphan Hydrobromide/Quinidine Sulfate) as an Adjunctive Therapy in Patients With Major Depressive Disorder With an Inadequate Response to Antidepressant Treatment
Study identification
- NCT ID
- NCT02153502
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
- Industry
- Enrollment
- 206 participants
Conditions and interventions
Conditions
Interventions
- AVP-786 (d6-dextromethorphan hydrobromide and quinidine sulfate combination) Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 30, 2014
- Primary completion
- Jan 31, 2016
- Completion
- Jan 31, 2016
- Last update posted
- Jul 12, 2026
2014 – 2016
United States locations
- U.S. sites
- 32
- U.S. states
- 14
- U.S. cities
- 29
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Birmingham | Alabama | 35213 | — |
| Not listed | Birmingham | Alabama | 35294 | — |
| Not listed | Bellflower | California | 90706 | — |
| Not listed | Costa Mesa | California | 92626 | — |
| Not listed | Garden Grove | California | 92845 | — |
| Not listed | Lomita | California | 90717 | — |
| Not listed | Oceanside | California | 92056 | — |
| Not listed | Riverside | California | 92506 | — |
| Not listed | Santa Ana | California | 92706 | — |
| Not listed | Sherman Oaks | California | 91403 | — |
| Not listed | Denver | Colorado | 80239 | — |
| Not listed | Bradenton | Florida | 34201 | — |
| Not listed | Jacksonville | Florida | 32256 | — |
| Not listed | Miami | Florida | 33155 | — |
| Not listed | Orange City | Florida | 32763 | — |
| Not listed | Orlando | Florida | 32801 | — |
| Not listed | Decatur | Georgia | 30030 | — |
| Not listed | Hoffman Estates | Illinois | 60169 | — |
| Not listed | Valparaiso | Indiana | 46383 | — |
| Not listed | Baltimore | Maryland | 21285 | — |
| Not listed | Glen Burnie | Maryland | 21061 | — |
| Not listed | Boston | Massachusetts | 02131 | — |
| Not listed | Brooklyn | New York | 11241 | — |
| Not listed | New York | New York | 10003 | — |
| Not listed | Staten Island | New York | 10312 | — |
| Not listed | Garfield Heights | Ohio | 44125 | — |
| Not listed | Oklahoma City | Oklahoma | 73103 | — |
| Not listed | Oklahoma City | Oklahoma | 73112 | — |
| Not listed | Tulsa | Oklahoma | 74101 | — |
| Not listed | Philadelphia | Pennsylvania | 19104 | — |
| Not listed | Philadelphia | Pennsylvania | 19139 | — |
| Not listed | Murray | Utah | 84123 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02153502, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 12, 2026 · Synced Jul 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02153502 live on ClinicalTrials.gov.