Pyridorin in Diabetic Nephropathy
Public ClinicalTrials.gov record NCT02156843. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study to Evaluate the Safety and Efficacy of Pyridorin (Pyridoxamine Dihydrochloride) in Subjects With Nephropathy Due to Type 2 Diabetes (PIONEER)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the safety and efficacy of oral Pyridorin 300 mg BID in reducing the rate of progression of nephropathy due to type 2 diabetes mellitus.
Study identification
- NCT ID
- NCT02156843
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 328 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2014 (Type not available)
- Primary completion
- Dec 2017 (Estimated)
- Completion
- Mar 2018 (Estimated)
- Last update posted
- Mar 9, 2016
2014 – 2018
United States locations
- U.S. sites
- 55
- U.S. states
- 26
- U.S. cities
- 50
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| CSG Investigational Site (#157) | Birmingham | Alabama | 35294 | — |
| CSG Investigational Site (#130) | Phoenix | Arizona | 85012 | — |
| CSG Investigational Site (#150) | Phoenix | Arizona | 85054 | — |
| CSG Investigational Site (#145) | Prescott | Arizona | 86301 | — |
| CSG Investigational Site (#142) | Tucson | Arizona | 85745 | — |
| CSG Investigational Site (#160) | Los Angeles | California | 90048 | — |
| CSG Investigational Site (#143) | Riverside | California | 92505 | — |
| CSG Investigational Site (#159) | Roseville | California | 95661 | — |
| CSG Investigational Site (#153) | Arvada | Colorado | 80002 | — |
| CSG Investigational Site (#118) | Aurora | Colorado | 80045 | — |
| CSG Investigational Site (#120) | Westminster | Colorado | 80031 | — |
| CSG Investigational Site (#158) | Waterbury | Connecticut | 06708 | — |
| CSG Investigational Site (#156) | Columbus | Georgia | 31901 | — |
| CSG Investigational Site (#113) | Chicago | Illinois | 60607 | — |
| CSG Investigational Site (#102) | Michigan City | Indiana | 46360 | — |
| CSG Investigational Site (#115) | New Orleans | Louisiana | 70112 | — |
| CSG Investigational Site (#147) | Greenbelt | Maryland | 20770 | — |
| CSG Investigational Site (#117) | Boston | Massachusetts | 02111 | — |
| CSG Investigational Site (#114) | Springfield | Massachusetts | 01107 | — |
| CSG Investigational Site (#111) | Detroit | Michigan | 48202 | — |
| CSG Investigational Site (#134) | Pontiac | Michigan | 48341 | — |
| CSG Investigational Site (#162) | Kansas City | Missouri | 64111 | — |
| CSG Investigational Site (#152) | Kansas City | Missouri | 64128 | — |
| CSG Investigational Site (#141) | Las Vegas | Nevada | 89115 | — |
| CSG Investigational Site (#128) | Buffalo | New York | 14215 | — |
| CSG Investigational Site (#136) | Northport | New York | 11768 | — |
| CSG Investigational Site (#154) | West Nyack | New York | 10994 | — |
| CSG Investigational Site (#108) | Asheville | North Carolina | 28801 | — |
| CSG Investigational Site (#116) | Charlotte | North Carolina | 28207 | — |
| CSG Investigational Site (#125) | Durham | North Carolina | 27710 | — |
| CSG Investigational Site (#155) | New Bern | North Carolina | 28562 | — |
| CSG Investigational Site (#127) | Winston-Salem | North Carolina | 27157 | — |
| CSG Investigational Site (#124) | Cincinnati | Ohio | 45267 | — |
| CSG Investigational Site (#151) | Cleveland | Ohio | 44106 | — |
| CSG Investigational Site (#123) | Cleveland | Ohio | 44195 | — |
| CSG Investigational Site (#106) | Columbus | Ohio | 43210 | — |
| CSG Investigational Site (#148) | Parma Heights | Ohio | 44130 | — |
| CSG Investigational Site (#101) | Philadelphia | Pennsylvania | 19104 | — |
| CSG Investigational Site (#149) | Pittsburgh | Pennsylvania | 15240 | — |
| CSG Investigational Site (#146) | Providence | Rhode Island | 02903 | — |
| CSG Investigational Site (#131) | Chattanooga | Tennessee | 37408 | — |
| CSG Investigational Site (#105) | Nashville | Tennessee | 37205 | — |
| CSG Investigational Site (#119) | Dallas | Texas | 75390 | — |
| CSG Investigational Site (#139) | Houston | Texas | 77004 | — |
| CSG Investigational Site (#133) | Houston | Texas | 77076 | — |
| CSG Investigational Site (#109) | Midland | Texas | 79707 | — |
| CSG Investigational Site (#132) | Salt Lake City | Utah | 84112 | — |
| CSG Investigational Site (#107) | Burlington | Vermont | 05401 | — |
| CSG Investigational Site (#129) | Charlottesville | Virginia | 22908 | — |
| CSG Investigational Site (#137) | Fairfax | Virginia | 22030 | — |
| CSG Investigational Site (#103) | Fairfax | Virginia | 22033 | — |
| CSG Investigational Site (#104) | Hampton | Virginia | 23666 | — |
| CSG Investigational Site (#144) | Richmond | Virginia | 23249 | — |
| CSG Investigational Site (#121) | Spokane | Washington | 99204 | — |
| CSG Investigational Site (#122) | Milwaukee | Wisconsin | 53295 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 82 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02156843, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 9, 2016 · Synced Sep 30, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02156843 live on ClinicalTrials.gov.