M6620 First in Human Study
Public ClinicalTrials.gov record NCT02157792. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-Label, First-in-Human Study of the Safety, Tolerability, and Pharmacokinetics of VX-970/M6620 in Combination With Cytotoxic Chemotherapy in Participants With Advanced Solid Tumors
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
An Open-Label, First-in-Human Study of the Safety, Tolerability, and Pharmacokinetics (PK) of M6620 in Combination With Cytotoxic Chemotherapy in Participants With Advanced Solid Tumors
Study identification
- NCT ID
- NCT02157792
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1
- Enrollment
- 200 participants
Conditions and interventions
Conditions
Interventions
- M6620 Drug
- Gemcitabine Drug
- Cisplatin Drug
- Etoposide Drug
- Carboplatin Drug
- Irinotecan Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 9, 2012
- Primary completion
- Mar 10, 2020
- Completion
- Mar 10, 2020
- Last update posted
- Mar 31, 2020
2012 – 2020
United States locations
- U.S. sites
- 24
- U.S. states
- 17
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic Arizona | Phoenix | Arizona | 85054 | — |
| Sharp Memorial Hospital | San Diego | California | 92123 | — |
| Not listed | Stanford | California | — | — |
| Rocky Mountain Cancer Centers, LLP | Denver | Colorado | 80218 | — |
| Emory University | Atlanta | Georgia | 30322 | — |
| Northwestern Center for Clinical Research | Chicago | Illinois | 60611 | — |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02215 | — |
| Breslin Cancer Center | Lansing | Michigan | 48910 | — |
| University Of Minnesota Hospital | Minneapolis | Minnesota | 55455 | — |
| Mayo Clinic - Rochester | Rochester | Minnesota | 55905 | — |
| Washington University in St. Louis | St Louis | Missouri | 63110 | — |
| Hackensack University Medical Center PARTNER | Hackensack | New Jersey | 07601 | — |
| Long Island Jewish Medical Center - Monter Cancer Center | Lake Success | New York | 11042 | — |
| University Hospitals Case Medical Center - Case Comprehensive Cancer Center at | Cleveland | Ohio | 44106 | — |
| OSU - James Comprehensive Cancer Center - Division of Hematology | Columbus | Ohio | 43210 | — |
| Greenville Health System | Greenville | South Carolina | 29605 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| US Oncology - Texas Oncology-Midtown - Austin Midtown | Austin | Texas | 78705 | — |
| Texas Oncology, P.A. | Dallas | Texas | 75231 | — |
| University of Texas M. D. Anderson Cancer Center - Investigational Cancer Therapeutics - Partner | Houston | Texas | 77030 | — |
| Texas Oncology San Antonio Medical Cente | San Antonio | Texas | 78240 | — |
| Virginia Cancer Specialists, PC | Fairfax | Virginia | 22031 | — |
| Virginia Oncology Associates - Hampton | Norfolk | Virginia | 23502 | — |
| Northwest Cancer Specialists , P.C. | Vancouver | Washington | 98684 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02157792, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 31, 2020 · Synced Sep 26, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02157792 live on ClinicalTrials.gov.