A Study to Evaluate Long-term Outcomes Following Treatment With ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) and ABT-333 With or Without Ribavirin (RBV) in Adults With Genotype 1 Chronic Hepatitis C Virus (HCV) Infection
Public ClinicalTrials.gov record NCT02167945. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-Label, Multicenter Study to Evaluate Long-term Outcomes With ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) and ABT-333 With or Without Ribavirin (RBV) in Adults With Genotype 1 Chronic Hepatitis C Virus (HCV) Infection (TOPAZ-II)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study was to evaluate the effect of treatment with ABT-450 co-formulated with ritonavir and ABT-267 (ABT-450/r/ABT-267) and ABT-333; 3-DAA regimen, with or without ribavirin (RBV) in adults with chronic hepatitis C virus genotype 1 (HCV GT1) infection.
Study identification
- NCT ID
- NCT02167945
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 615 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years to 99 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 12, 2014 (Actual)
- Primary completion
- May 13, 2021 (Actual)
- Completion
- May 13, 2021 (Actual)
- Last update posted
- Jul 19, 2022
2014 – 2021
United States locations
- U.S. sites
- 48
- U.S. states
- 26
- U.S. cities
- 43
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| St. Josephs Hospital and Med Center /ID# 127800 | Phoenix | Arizona | 85013 | — |
| Franco Felizarta, Md /Id# 126569 | Bakersfield | California | 93301 | — |
| Ruane Clinical Research Group /ID# 126577 | Los Angeles | California | 90036 | — |
| California Pacific Medical Center /ID# 128681 | San Francisco | California | 94115 | — |
| Univ of Colorado Cancer Center /ID# 126568 | Aurora | Colorado | 80045 | — |
| Medstar Health Research Institute /ID# 128683 | Washington D.C. | District of Columbia | 20010 | — |
| Bach and Godofsky Infec Dis /ID# 128685 | Bradenton | Florida | 34209 | — |
| University of Florida - Archer /ID# 127787 | Gainesville | Florida | 32610 | — |
| Encore Borland-Groover Clinical Research /Id# 127781 | Jacksonville | Florida | 32256 | — |
| University of Miami /ID# 127622 | Miami | Florida | 33136 | — |
| South Florida Ctr Gastro, P.A. /ID# 126567 | Wellington | Florida | 33414 | — |
| Atlanta Gastro Assoc /ID# 126571 | Atlanta | Georgia | 30342 | — |
| Northwestern University Feinberg School of Medicine /ID# 128684 | Chicago | Illinois | 60611-2927 | — |
| The University of Chicago Medical Center /ID# 126576 | Chicago | Illinois | 60637-1443 | — |
| Duplicate_Indiana University Health /ID# 126573 | Indianapolis | Indiana | 46202 | — |
| Tulane University /ID# 127779 | New Orleans | Louisiana | 70112-2699 | — |
| Louisana Research Center, LLC /ID# 126561 | Shreveport | Louisiana | 71105-6800 | — |
| Johns Hopkins University /ID# 127791 | Baltimore | Maryland | 21287 | — |
| Digestive Disease Associates - Catonsville /ID# 127624 | Catonsville | Maryland | 21228 | — |
| Beth Israel Deaconess Medical Center /ID# 126560 | Boston | Massachusetts | 02215-5400 | — |
| Henry Ford Health System /ID# 127783 | Detroit | Michigan | 48202 | — |
| Minnesota Gastroenterology PA /ID# 126579 | Plymouth | Minnesota | 55446 | — |
| St. Louis University /ID# 126564 | St Louis | Missouri | 63104 | — |
| AGA Clinical Research Associates, LLC /ID# 126578 | Egg Harbor | New Jersey | 08234 | — |
| Rutgers New Jersey School of Medicine /ID# 128686 | Newark | New Jersey | 07103 | — |
| University of New Mexico /ID# 128859 | Albuquerque | New Mexico | 87102-4517 | — |
| Southwest Care Center /ID# 127784 | Santa Fe | New Mexico | 87505 | — |
| North Shore University Hospital /ID# 126565 | New Hyde Park | New York | 11040 | — |
| The Mount Sinai Hospital /ID# 128682 | New York | New York | 10029 | — |
| Columbia Univ Medical Center /ID# 126566 | New York | New York | 10032-3725 | — |
| Columbia Univ Medical Center /ID# 127621 | New York | New York | 10032-3725 | — |
| Premier Medical Group - GI Division /ID# 127793 | Poughkeepsie | New York | 12601 | — |
| Univ Rochester Med Ctr /ID# 127655 | Rochester | New York | 14642 | — |
| Atrium Health Carolinas Medical Center /ID# 127632 | Charlotte | North Carolina | 28203 | — |
| Carolinas Center For Liver Dis /ID# 127788 | Statesville | North Carolina | 28677 | — |
| University of Cincinnati Physicians Company, LLC /ID# 127790 | Cincinnati | Ohio | 45267-2827 | — |
| Options Health Research, LLC /ID# 127630 | Tulsa | Oklahoma | 74104 | — |
| University Gastroenterology /ID# 127789 | Providence | Rhode Island | 02905 | — |
| Gastro One /ID# 127792 | Germantown | Tennessee | 38138 | — |
| Inquest Clinical Research /ID# 126574 | Baytown | Texas | 77521-2415 | — |
| Cure C Consortium /ID# 126570 | Houston | Texas | 77004 | — |
| Liver Associates of Texas, P.A /ID# 126563 | Houston | Texas | 77030-2783 | — |
| Austin Institute for Clinical Research /ID# 126562 | Pflugerville | Texas | 78660 | — |
| TX Liver Inst, Americ Res Corp /ID# 127623 | San Antonio | Texas | 78215 | — |
| Clinical Research Ctrs America /ID# 127780 | Murray | Utah | 84123 | — |
| Virginia Mason - Seattle Orthapedics /ID# 130288 | Seattle | Washington | 98101 | — |
| University of Washington /ID# 127785 | Seattle | Washington | 98109 | — |
| Dean Clinic /ID# 126575 | Madison | Wisconsin | 53715 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02167945, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 19, 2022 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02167945 live on ClinicalTrials.gov.