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Terminated Phase 1 Interventional Results available

Refametinib (BAY86-9766) in Combination With Regorafenib (Stivarga, BAY73-4506) in Patients With Advanced or Metastatic Cancer

ClinicalTrials.gov ID: NCT02168777

Public ClinicalTrials.gov record NCT02168777. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 27, 2026, 2:54 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1b/2, Multi-center, Uncontrolled, Open-label, Dose Escalation Study of Refametinib (BAY86-9766) in Combination With Regorafenib (BAY73-4506) in Patients With Advanced or Metastatic Cancer

Study identification

NCT ID
NCT02168777
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1
Lead sponsor
Bayer
Industry
Enrollment
20 participants

Conditions and interventions

Conditions

Interventions

  • Refametinib (BAY86-9766) Drug
  • Regorafenib (Stivarga, BAY73-4506) Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 22, 2014
Primary completion
Oct 22, 2015
Completion
Apr 4, 2016
Last update posted
Jan 25, 2018

2014 – 2016

United States locations

U.S. sites
5
U.S. states
5
U.S. cities
5
Facility City State ZIP Site status
Not listed New Haven Connecticut 06510
Not listed Detroit Michigan 48201
Not listed St Louis Missouri 63110
Not listed Chapel Hill North Carolina 27599
Not listed Houston Texas 77030

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02168777, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 25, 2018 · Synced Jun 27, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02168777 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →