24 Week Efficacy and Safety Study of Empagliflozin (BI 10773) in Hypertensive Black/African American Patients With Type 2 Diabetes Mellitus and Hypertension
Public ClinicalTrials.gov record NCT02182830. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomised, Double-blind, Placebo-controlled, Parallel Group, Efficacy and Safety Study of Empagliflozin (10mg, 25mg) Administered Orally, Once Daily Over 24 Weeks in Hypertensive Black/African American Patients With Type 2 Diabetes Mellitus
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This trial is designed to investigate the efficacy and safety of empagliflozin compared with placebo in hypertensive black/African Americans with type 2 Diabetes Mellitus. Since hyperglycaemia and hypertension are key risk factors for both micro- and macrovascular complications, assessment of both glucose and BP lowering effects of empagliflozin in hypertensive African American patients with type 2 Diabetes Mellitus could provide clinically highly relevant, new information for the use of empagliflozin. Essential hypertension is four times more common in African Americans than in Caucasians. One of the risk factors for hypertension is sodium sensitivity and approximately one third of the essential hypertensive population is responsive to sodium intake. There is a higher association of hypertension with sodium sensitivity in African American patients with type 2 Diabetes Mellitus. The treatment duration of this trial (24 weeks) will enable assessment of the clinically relevant endpoint of a decrease in HbA1c, a well accepted measurement of chronic glycaemic control and the key secondary endpoints of decreases in systolic BP (SBP) and diastolic BP (DBP) at 12 and 24 weeks.
Study identification
- NCT ID
- NCT02182830
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 166 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 25, 2014 (Actual)
- Primary completion
- May 18, 2017 (Actual)
- Completion
- May 18, 2017 (Actual)
- Last update posted
- Jul 31, 2018
2014 – 2017
United States locations
- U.S. sites
- 92
- U.S. states
- 25
- U.S. cities
- 65
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35205 | — |
| Clinical Research Advantage, Inc./Rita B. Chuang, MD, LLC | Birmingham | Alabama | 35211 | — |
| Longwood Research | Huntsville | Alabama | 35801 | — |
| Internal Medicine Center, LLC | Mobile | Alabama | 36608 | — |
| Mobile Medical and Diagnostic Center | Mobile | Alabama | 36617 | — |
| University of South Alabama | Mobile | Alabama | 36617 | — |
| Cardiology and Medicine Clinic | Little Rock | Arkansas | 72204 | — |
| Larry Watkins, M .D. | Little Rock | Arkansas | 72205 | — |
| eStudySite | Chula Vista | California | 91911 | — |
| Torrance Clinical Research Institute Inc. | Lomita | California | 90717 | — |
| Long Beach Center for Clinical Research | Long Beach | California | 90807 | — |
| MD Clinical Trials | Los Angeles | California | 90025 | — |
| Office of Dr. Alexander Ford, M.D. | Los Angeles | California | 90035 | — |
| Diabetes Associates Medical Group | Orange | California | 92868 | — |
| Integrated Research Group, Inc. | Riverside | California | 92506 | — |
| Clinical Trials Research | Sacramento | California | 95821 | — |
| Orange County Research Center | Tustin | California | 92780 | — |
| Lynn Institute of Denver | Denver | Colorado | 80246 | — |
| Pines Clinical Research Inc. | Hollywood | Florida | 33024 | — |
| UF Health Jacksonville | Jacksonville | Florida | 32207 | — |
| Care Partners Clinical Research LLC | Jacksonville | Florida | 32277 | — |
| Sunshine Research Center | Opa-locka | Florida | 33054 | — |
| Central Florida Internist | Orlando | Florida | 32811 | — |
| Accord Clinical Research, LLC | Port Orange | Florida | 32129 | — |
| International Clinical Research - US, LLC | Sanford | Florida | 32771 | — |
| Meridien Research | St. Petersburg | Florida | 33709 | — |
| Alternative Solutions Medical Research and Prevention Center | St. Petersburg | Florida | 33711 | — |
| Meridien Research | Tampa | Florida | 33634 | — |
| Grady Memorial Hospital | Atlanta | Georgia | 30303 | — |
| Morehouse School of Medicine | Atlanta | Georgia | 30310 | — |
| Atlanta Center | Atlanta | Georgia | 30331 | — |
| Atlanta Clinical Research Centers | Atlanta | Georgia | 30342 | — |
| Albert F. Johary MD, PC | Dunwoody | Georgia | 30338 | — |
| Sestron Clinical Research | Marietta | Georgia | 30060 | — |
| Clinical Research Advantage, Inc./Rita B. Chuang, MD, LLC | Marietta | Georgia | 30067 | — |
| WR-Mount Vernon Clinical Research, LLC | Sandy Springs | Georgia | 30328 | — |
| Eagle's Landing Diabetes and Endocrinology | Stockbridge | Georgia | 30281 | — |
| Cedar Crosse Research Center | Chicago | Illinois | 60607 | — |
| John H. Stroger Jr. Hospital of Cook Country | Chicago | Illinois | 60612 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| Investigators Research Group, LLC | Brownsburg | Indiana | 46112 | — |
| Centex Studies, Inc. | Lake Charles | Louisiana | 70601 | — |
| Gulf Regional Research and Education Services, LLC | Metairie | Louisiana | 70002 | — |
| New Orleans Center for Clinical Research | New Orleans | Louisiana | 70119 | — |
| University of Maryland School of Medicine | Baltimore | Maryland | 21201 | — |
| American Institute of Research Studies | Baltimore | Maryland | 21218 | — |
| Phillips Medical Services, PLLC | Jackson | Mississippi | 39209 | — |
| Mercy Research | Washington | Missouri | 63090-4700 | — |
| Quality Clinical Research Inc | Omaha | Nebraska | 68114 | — |
| Accent Clinical Trials | Las Vegas | Nevada | 89106 | — |
| Lovelace Scientific Resources, Inc. | Albuquerque | New Mexico | 87108 | — |
| Offic of Dr. Eric Cheng | Brooklyn | New York | 11203-1203 | — |
| Healthwise Medical Associates | Brooklyn | New York | 11206 | — |
| Modern Medical | Brooklyn | New York | 11207 | — |
| Erie County Medical Center | Buffalo | New York | 14215 | — |
| Scott Research, Inc. | Laurelton | New York | 11413 | — |
| Medex Healthcare Research, Inc. | New York | New York | 10036 | — |
| Laurelton Heart Specialist, PC | Rosedale | New York | 11422 | — |
| Metrolina Internal Medicine, PA | Charlotte | North Carolina | 28204 | — |
| PhysiqueMed Clinical Trials | Greensboro | North Carolina | 27405 | — |
| Triad Clinical Trials | Greensboro | North Carolina | 27410 | — |
| Peters Medical Research | High Point | North Carolina | 27262 | — |
| High Point Clinical Trials Center | High Point | North Carolina | 27265 | — |
| Coastal Carolina Health Care, P.A. | New Bern | North Carolina | 28562 | — |
| Hometown Urgent Care | Columbus | Ohio | 43214 | — |
| Dayton Clinical Research | Dayton | Ohio | 45406 | — |
| Today Clinical Research, Oklahoma City | Oklahoma City | Oklahoma | 73129 | — |
| Suburban Research Associates | Media | Pennsylvania | 19063 | — |
| Temple University School of Medicine | Philadelphia | Pennsylvania | 19140 | — |
| Medical Research South | Charleston | South Carolina | 29407 | — |
| TLM Medical Services, LLC | Columbia | South Carolina | 29204 | — |
| Amistad Clinical Research Center | Columbia | South Carolina | 29223 | — |
| Greenville Pharmaceutical Rsch | Greenville | South Carolina | 29615 | — |
| Mountain View Clinical Research | Greer | South Carolina | 29651 | — |
| Berkley Family Practice | Moncks Corner | South Carolina | 29461 | — |
| Carolina Cardiology Clinical Research Institute, LLC | Rock Hill | South Carolina | 29732 | — |
| Community Research Partners, Inc | Varnville | South Carolina | 29944 | — |
| Memphis Veterans Affairs Medical Center | Memphis | Tennessee | 38104 | — |
| The Green Clinic PC | Memphis | Tennessee | 38119 | — |
| Southwind Medical Specialists | Memphis | Tennessee | 38125 | — |
| University of Tennessee | Memphis | Tennessee | 38163 | — |
| Diagnostic Clinic of Houston | Houston | Texas | 77004 | — |
| Cullen Family Practice, PLLC | Houston | Texas | 77051 | — |
| Centex Studies, Inc. | Houston | Texas | 77058 | — |
| Texas Center for Drug Development, Inc. | Houston | Texas | 77081 | — |
| Kelsey-Seybold Clinic | Houston | Texas | 77096 | — |
| Hillcrest Family Health Center | Waco | Texas | 76710 | — |
| Millennium Clinical Trials LLC | Arlington | Virginia | 22203 | — |
| York Clinical Research, LLC | Norfolk | Virginia | 23510 | — |
| Dominion Medical Associates, Inc. | Richmond | Virginia | 23219 | — |
| Clinical Research Partners, LLC | Richmond | Virginia | 23235 | — |
| Family Medical Clinic | Milwaukee | Wisconsin | 53216 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02182830, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 31, 2018 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02182830 live on ClinicalTrials.gov.