ClinicalTrials.gov record
Diuretic Comparison Project
ClinicalTrials.gov ID: NCT02185417
Public ClinicalTrials.gov record NCT02185417. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
CSP #597 - Diuretic Comparison Project
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The Diuretic Comparison Project aimed to evaluate whether chlorthalidone, as compared with hydrochlorothiazide, would reduce the risk of major nonfatal cardiovascular disease outcomes and non-cancer-related deaths in older patients with hypertension who were receiving hydrochlorothiazide at baseline. The investigators incorporated the pragmatic methods used by the Department of Veterans Affairs (VA) Healthcare System to provide a real-world assessment of the effectiveness of chlorthalidone as compared with hydrochlorothiazide in routine clinical care.
Study identification
- NCT ID
- NCT02185417
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 20,723 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 65 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 14, 2016
- Primary completion
- Oct 14, 2022
- Completion
- Dec 28, 2022
- Last update posted
- May 21, 2024
2016 – 2022
United States locations
- U.S. sites
- 69
- U.S. states
- 40
- U.S. cities
- 67
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Birmingham VA Medical Center, Birmingham, AL | Birmingham | Alabama | 35233 | — |
| Alaska VA Healthcare System, Anchorage, AK | Anchorage | Alaska | 99504 | — |
| Veterans Health Care System of the Ozarks, Fayetteville, AR | Fayetteville | Arkansas | 72703 | — |
| Central Arkansas VHS John L. McClellan Memorial Veterans Hospital, Little Rock, AR | Little Rock | Arkansas | 72205-5484 | — |
| VA Central California Health Care System, Fresno, CA | Fresno | California | 93703 | — |
| VA Long Beach Healthcare System, Long Beach, CA | Long Beach | California | 90822 | — |
| VA Palo Alto Health Care System, Palo Alto, CA | Palo Alto | California | 94304-1290 | — |
| VA Greater Los Angeles Healthcare System, West Los Angeles, CA | West Los Angeles | California | 90073 | — |
| Rocky Mountain Regional VA Medical Center, Aurora, CO | Aurora | Colorado | 80045 | — |
| Grand Junction VA Medical Center, Grand Junction, CO | Grand Junction | Colorado | 81501 | — |
| VA Connecticut Healthcare System West Haven Campus, West Haven, CT | West Haven | Connecticut | 06516 | — |
| Wilmington VA Medical Center, Wilmington, DE | Wilmington | Delaware | 19805 | — |
| Washington DC VA Medical Center, Washington, DC | Washington D.C. | District of Columbia | 20422 | — |
| Bay Pines VA Healthcare System, Pay Pines, FL | Bay Pines | Florida | 33744 | — |
| North Florida/South Georgia Veterans Health System, Gainesville, FL | Gainesville | Florida | 32608 | — |
| VA Pacific Islands Health Care System, Honolulu, HI | Honolulu | Hawaii | 96819-1522 | — |
| Boise VA Medical Center, Boise, ID | Boise | Idaho | 83702 | — |
| VA Illiana Health Care System, Danville, IL | Danville | Illinois | 61832 | — |
| Edward Hines Jr. VA Hospital, Hines, IL | Hines | Illinois | 60141-5000 | — |
| Captain James A. Lovell Federal Health Care Center, North Chicago, IL | North Chicago | Illinois | 60064 | — |
| Richard L. Roudebush VA Medical Center, Indianapolis, IN | Indianapolis | Indiana | 46202-2884 | — |
| VA Central Iowa Health Care System, Des Moines, IA | Des Moines | Iowa | 50310-5774 | — |
| Iowa City VA Health Care System, Iowa City, IA | Iowa City | Iowa | 52246-2208 | — |
| Maine VA Medical Center, Augusta, ME | Togus | Maine | 04330 | — |
| Rehabilitation R&D Service, Baltimore, MD | Baltimore | Maryland | 21202 | — |
| Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA | Bedford | Massachusetts | 01730 | — |
| VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA | Boston | Massachusetts | 02130 | — |
| Aleda E. Lutz VA Medical Center, Saginaw, MI | Saginaw | Michigan | 48602 | — |
| Minneapolis VA Health Care System, Minneapolis, MN | Minneapolis | Minnesota | 55417-2309 | — |
| Minneapolis VA Health Care System, Minneapolis, MN | Minneapolis | Minnesota | 55417 | — |
| St. Cloud VA Health Care System, St. Cloud, MN | Saint Cloud | Minnesota | 56303 | — |
| VA Gulf Coast Veterans Health Care System, Biloxi, MS | Biloxi | Mississippi | 39531 | — |
| Kansas City VA Medical Center, Kansas City, MO | Kansas City | Missouri | 64128 | — |
| St. Louis VA Medical Center John Cochran Division, St. Louis, MO | St Louis | Missouri | 63106 | — |
| Omaha VA Nebraska-Western Iowa Health Care System, Omaha, NE | Omaha | Nebraska | 68105-1873 | — |
| Manchester VA Medical Center, Manchester, NH | Manchester | New Hampshire | 03104 | — |
| New Mexico VA Health Care System, Albuquerque, NM | Albuquerque | New Mexico | 87108-5153 | — |
| Albany VA Medical Center Samuel S. Stratton, Albany, NY | Albany | New York | 12208 | — |
| Manhattan Campus of the VA NY Harbor Healthcare System, New York, NY | New York | New York | 10010 | — |
| Syracuse VA Medical Center, Syracuse, NY | Syracuse | New York | 13210 | — |
| Durham VA Medical Center, Durham, NC | Durham | North Carolina | 27705 | — |
| Fargo VA Healthcare System, Fargo, ND | Fargo | North Dakota | 58102 | — |
| Cincinnati VA Medical Center, Cincinnati, OH | Cincinnati | Ohio | 45220 | — |
| Louis Stokes VA Medical Center, Cleveland, OH | Cleveland | Ohio | 44106 | — |
| Dayton VA Medical Center, Dayton, OH | Dayton | Ohio | 45428 | — |
| Jackson C. Montgomery VA Medical Center, Muskogee, OK | Muskogee | Oklahoma | 74401 | — |
| VA Portland Health Care System, Portland, OR | Portland | Oregon | 97239 | — |
| VA Roseburg Healthcare System, Roseburg, OR | Roseburg | Oregon | 97471 | — |
| VA Southern Oregon Rehabilitation Center and Clinics, White City, OR | White City | Oregon | 97503 | — |
| Coatesville VA Medical Center, Coatesville, PA | Coatesville | Pennsylvania | 19320 | — |
| Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA | Philadelphia | Pennsylvania | 19104 | — |
| VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA | Pittsburgh | Pennsylvania | 15240 | — |
| Wilkes-Barre VA Medical Center, Wilkes-Barre, PA | Wilkes-Barre | Pennsylvania | 18711 | — |
| Ralph H. Johnson VA Medical Center, Charleston, SC | Charleston | South Carolina | 29401-5799 | — |
| Wm. Jennings Bryan Dorn VA Medical Center, Columbia, SC | Columbia | South Carolina | 29209 | — |
| VA Black Hills Health Care System Fort Meade Campus, Fort Meade, SD | Sturgis | South Dakota | 57741 | — |
| Memphis VA Medical Center, Memphis, TN | Memphis | Tennessee | 38104-2127 | — |
| Memphis VA Medical Center, Memphis, TN | Memphis | Tennessee | 38104 | — |
| Tennessee Valley Healthcare System Nashville Campus, Nashville, TN | Nashville | Tennessee | 37212-2637 | — |
| VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX | Dallas | Texas | 75216 | — |
| Michael E. DeBakey VA Medical Center, Houston, TX | Houston | Texas | 77030 | — |
| South Texas Health Care System, San Antonio, TX | San Antonio | Texas | 78229 | — |
| White River Junction VA Medical Center, White River Junction, VT | White River Junction | Vermont | 05009-0001 | — |
| Hampton VA Medical Center, Hampton, VA | Hampton | Virginia | 23667 | — |
| Huntington VA Medical Center, Huntington, WV | Huntington | West Virginia | 25704 | — |
| William S. Middleton Memorial Veterans Hospital, Madison, WI | Madison | Wisconsin | 53705 | — |
| Clement J. Zablocki VA Medical Center, Milwaukee, WI | Milwaukee | Wisconsin | 53295-1000 | — |
| Tomah VA Medical Center, Tomah, WI | Tomah | Wisconsin | 54660 | — |
| Sheridan VA Medical Center, Sheridan, WY | Sheridan | Wyoming | 82801 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02185417, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 21, 2024 · Synced Sep 3, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02185417 live on ClinicalTrials.gov.