Ceritinib (LDK378) for Patients Whose Tumors Have Aberrations in ALK or ROS1 (SIGNATURE)
Public ClinicalTrials.gov record NCT02186821. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Modular Phase II Study to Link Targeted Therapy to Patients With Pathway Activated Tumors: Module - 7 Ceritinib (LDK378) for Patients Whose Tumors Have Aberrations in ALK or ROS1
Study identification
- NCT ID
- NCT02186821
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Enrollment
- 47 participants
Conditions and interventions
Conditions
Interventions
- Ceritinib Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 16, 2014
- Primary completion
- Dec 12, 2017
- Completion
- Dec 12, 2017
- Last update posted
- Apr 7, 2021
2014 – 2017
United States locations
- U.S. sites
- 21
- U.S. states
- 18
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| St Joseph Heritage Healthcare St. Joseph Heritage | Santa Rosa | California | 94503 | — |
| Sarah Cannon Research Institute | Denver | Colorado | 80218 | — |
| Rocky Mountain Cancer Centers Dept of Rocky Mountain (2) | Greenwood Village | Colorado | — | — |
| Florida Cancer Specialists Florida Cancer Specialists (31 | Fort Myers | Florida | 33901 | — |
| Northwestern University Northwestern (6) | Chicago | Illinois | 60611 | — |
| Physicians Clinic of Iowa | Cedar Rapids | Iowa | 52403 | — |
| Holy Cross Hospital Holy Cross (2) | Silver Spring | Maryland | 20910 | — |
| Southeast Nebraska Oncology | Lincoln | Nebraska | 68510 | — |
| Comprehensive Cancer Centers of Nevada CCC of Nevada (1) | Las Vegas | Nevada | 89109 | — |
| Duke University Medical Center Seeley G. Mudd Bldg. | Durham | North Carolina | 27710 | — |
| Wake Forest Baptist Health Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| Sanford Hematology Oncology | Fargo | North Dakota | 58122 | — |
| Columbus Hematology and Oncology PA Columbus Hem and Onc (2) | Columbus | Ohio | 39705 | — |
| Andrew and Patel Associates | Camp Hill | Pennsylvania | 17011 | — |
| Rhode Island Hospital Rhode Island Hosp. (2) | Providence | Rhode Island | 02903 | — |
| Sanford University of South Dakota Medical Center Sanford Clinical Research | Sioux Falls | South Dakota | 57104 | — |
| Oncology Consultants Oncology Group | Houston | Texas | 77024 | — |
| MD Anderson Cancer Center/University of Texas MD Anderson Cancer Center (3) | Houston | Texas | 77030 | — |
| Utah Cancer Specialists Utah Cancer Specialists | Salt Lake City | Utah | 84106 | — |
| Swedish Cancer Institute Swedish Cancer Institute | Seattle | Washington | 98104 | — |
| Aurora Research Institute | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02186821, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 7, 2021 · Synced Jul 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02186821 live on ClinicalTrials.gov.