ClinicalTrials.gov record
Efficacy and Safety of Rivipansel (GMI-1070) in the Treatment of Vaso-Occlusive Crisis in Hospitalized Subjects With Sickle Cell Disease
ClinicalTrials.gov ID: NCT02187003
Public ClinicalTrials.gov record NCT02187003. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multicenter ,Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Rivipansel (GMI-1070) in the Treatment of Vaso-Occlusive Crisis in Hospitalized Subjects With Sickle Cell Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a clinical study evaluating the efficacy and safety of rivipansel (GMI-1070) in treating subjects with sickle cell disease (SCD) who are 6 years of age or older experiencing a pain crisis necessitating hospitalization.
Study identification
- NCT ID
- NCT02187003
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 345 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 6 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 16, 2015
- Primary completion
- May 2, 2019
- Completion
- Jun 26, 2019
- Last update posted
- Mar 10, 2025
2015 – 2019
United States locations
- U.S. sites
- 126
- U.S. states
- 26
- U.S. cities
- 43
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of South Alabama Children's and Women's Hospital | Mobile | Alabama | 36604 | — |
| Arkansas Children's Hospital Research Pharmacy | Little Rock | Arkansas | 72202 | — |
| Arkansas Children's Hospital | Little Rock | Arkansas | 72202 | — |
| UCSF Benioff Children's Hospital Oakland | Oakland | California | 94609 | — |
| UC Davis Medical Center Main Hospital | Sacramento | California | 95817 | — |
| UC Davis Medical Center | Sacramento | California | 95817 | — |
| University of California Davis Medical Center | Sacramento | California | 95817 | — |
| University of Colorado CTRC | Aurora | Colorado | 80045 | — |
| University of Colorado Hospital | Aurora | Colorado | 80045 | — |
| Howard University Center for Sickle Cell Disease | Washington D.C. | District of Columbia | 20001 | — |
| Medstar Health Research Institute | Washington D.C. | District of Columbia | 20010 | — |
| Howard University Hospital | Washington D.C. | District of Columbia | 20060 | — |
| Golisano Children's Hospital of Southwest Florida | Fort Myers | Florida | 33908 | — |
| UF Health Davis Cancer Pavillion and Shands Med Plaza | Gainesville | Florida | 32608 | — |
| UF Health Shands Cancer Hospital | Gainesville | Florida | 32608 | — |
| UF Health Shands Hospital | Gainesville | Florida | 32610 | — |
| Jackson Memorial Hospital | Miami | Florida | 33136 | — |
| University Of Miami | Miami | Florida | 33136 | — |
| Investigational Drug Service Tampa General Hospital | Tampa | Florida | 33606 | — |
| Tampa General Hospital Center of Research Excellence | Tampa | Florida | 33606 | — |
| Tampa General Hospital | Tampa | Florida | 33606 | — |
| University of South Florida | Tampa | Florida | 33606 | — |
| St. Joseph's Children's Hospital | Tampa | Florida | 33607 | — |
| Children's Hematology and Oncology Associates | West Palm Beach | Florida | 33407 | — |
| St. Mary's Medical Center | West Palm Beach | Florida | 33407 | — |
| Children's Healthcare of Atlanta Aflac Cancer and Blood Disorders Center | Atlanta | Georgia | 30303 | — |
| Grady Health System | Atlanta | Georgia | 30303 | — |
| Children's Healthcare of Atlanta Aflac Cancer and Blood Disorders Center | Atlanta | Georgia | 30322 | — |
| Emory Children's Center | Atlanta | Georgia | 30322 | — |
| Children's Healthcare of Atlanta Aflac Cancer and Blood Disorders Center | Atlanta | Georgia | 30342 | — |
| Children's Healthcare of Atlanta: Scottish Rite Campus | Atlanta | Georgia | 30342 | — |
| Augusta University Clinical Research Pharmacy | Augusta | Georgia | 30912 | — |
| Augusta University Medical Center | Augusta | Georgia | 30912 | — |
| Augusta University | Augusta | Georgia | 30912 | — |
| Memorial Family Medicine Ctr. @Memorial Health Univ Med Ct | Savannah | Georgia | 31404 | — |
| Memorial Health University Medical Center | Savannah | Georgia | 31404 | — |
| University of Illinois at Chicago Clinical Research Center | Chicago | Illinois | 60612 | — |
| University of Illinois Hospital and Health Sciences System | Chicago | Illinois | 60612 | — |
| The University of Chicago/Comer Children's Hospital | Chicago | Illinois | 60637 | — |
| University of Chicago, Investigational Drug Service Pharmacy | Chicago | Illinois | 60637 | — |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | — |
| Kosair Charities Pediatric Clinical Research Unit | Louisville | Kentucky | 40202 | — |
| Norton Children´s Hospital | Louisville | Kentucky | 40202 | — |
| The Novak Center for Children's Health | Louisville | Kentucky | 40202 | — |
| University of Louisville Health Sciences Center | Louisville | Kentucky | 40202 | — |
| University of Louisville Physicians Pediatric Hematology Oncology | Louisville | Kentucky | 40202 | — |
| Our Lady of the Lake Regional Medical Center | Baton Rouge | Louisiana | 70808 | — |
| St. Jude Affiliate Clinic | Baton Rouge | Louisiana | 70808 | — |
| Our Lady of the Lake Physician Group-Medical Oncology | Baton Rouge | Louisiana | 70809 | — |
| University of Maryland Medical System Investigational Pharmacy | Baltimore | Maryland | 21201 | — |
| University of Maryland Medical System | Baltimore | Maryland | 21201 | — |
| Johns Hopkins Medicine | Baltimore | Maryland | 21205 | — |
| The Johns Hopkins University School of Medicine | Baltimore | Maryland | 21205 | — |
| The Johns Hopkins Hospital | Baltimore | Maryland | 21287-6180 | — |
| Johns Hopkins Medicine | Baltimore | Maryland | 21287 | — |
| Boston Children's Hospital | Boston | Massachusetts | 02115 | — |
| Brigham and Womens Hospital | Boston | Massachusetts | 02115 | — |
| Center for Clinical Investigation, Brigham & Women's Hospital | Boston | Massachusetts | 02115 | — |
| Investigational Drug Services | Boston | Massachusetts | 02115 | — |
| Boston Medical Center E7E | Boston | Massachusetts | 02118 | — |
| Boston Medical Center | Boston | Massachusetts | 02118 | — |
| Boston University Medical Center | Boston | Massachusetts | 02118 | — |
| Children's Hospital of Michigan | Detroit | Michigan | 48201 | — |
| Detroit Medical Center Pharmacy | Detroit | Michigan | 48201 | — |
| Wayne State University / Detroit Receiving Hospital | Detroit | Michigan | 48201 | — |
| University of Mississippi Medical Center-Outpatient Clinical Research Unit | Jackson | Mississippi | 39216 | — |
| University Of Mississippi Medical Center | Jackson | Mississippi | 39216 | — |
| Children's Mercy Hospital | Kansas City | Missouri | 64108 | — |
| Center for Outpatient Health | St Louis | Missouri | 63108 | — |
| Barnes-Jewish Hospital Department of Pharmacy | St Louis | Missouri | 63110 | — |
| Barnes-Jewish Hospital | St Louis | Missouri | 63110 | — |
| Center for Advanced Medicine | St Louis | Missouri | 63110 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Bristol Myers Squibb Children's Hospital at Robert Wood Johnson University Hospital | New Brunswick | New Jersey | 08901 | — |
| Rutgers-Robert Wood Johnson Medical School | New Brunswick | New Jersey | 08901 | — |
| Rutgers Cancer Institute Of New Jersey | New Brunswick | New Jersey | 08903 | — |
| Kings County Hospital Center - Pharmacy Department | Brooklyn | New York | 11203 | — |
| Kings County Hospital Center | Brooklyn | New York | 11203 | — |
| State University of New York (SUNY) - Downstate Medical Center | Brooklyn | New York | 11203 | — |
| SUNY Downstate Medical Center University Hospital of Brooklyn | Brooklyn | New York | 11203 | — |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | — |
| Columbia University Medical Center Research Pharmacy | New York | New York | 10032 | — |
| MS CHONY Pediatric Emergency Department | New York | New York | 10032 | — |
| MS CHONY Pediatric Hematology/Oncology Unit | New York | New York | 10032 | — |
| Staten Island University Hospital | Staten Island | New York | 10305 | — |
| Jacobi Medical Center | The Bronx | New York | 10461 | — |
| Duke University Hospital | Durham | North Carolina | 27710 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| East Carolina University Brody School of Medicine | Greenville | North Carolina | 27834 | — |
| Leo W. Jenkins Cancer Center | Greenville | North Carolina | 27834 | — |
| Vidant Medical Center | Greenville | North Carolina | 27834 | — |
| University of Cincinnati Medical Center/ Investigational Pharmacy | Cincinnati | Ohio | 45219 | — |
| University of Cincinnati Medical Center/Research Office | Cincinnati | Ohio | 45219 | — |
| University of Cincinnati Medical Center | Cincinnati | Ohio | 45219 | — |
| University of Cincinnati Physicians Company LLC | Cincinnati | Ohio | 45219 | — |
| University of Cincinnati- Hoxworth Building | Cincinnati | Ohio | 45219 | — |
| UC Health Ridgeway Hospital | Cincinnati | Ohio | 45229 | — |
| The Ohio State University Wexner Medical Center East | Columbus | Ohio | 43203 | — |
| Nationwide Childrens Hospital | Columbus | Ohio | 43205 | — |
| The Ohio State University Investigational Drug Services | Columbus | Ohio | 43210 | — |
| The Ohio State University James Comprehensive Cancer Hospital & Solove Research Institute | Columbus | Ohio | 43210 | — |
| The Ohio State University Wexner Medical Center | Columbus | Ohio | 43210 | — |
| Five Rivers Medical Surgical Health Center | Dayton | Ohio | 45402 | — |
| Miami Valley Hospital | Dayton | Ohio | 45409 | — |
| Einstein Medical Center Philadelphia | Philadelphia | Pennsylvania | 19141 | — |
| UPMC Presbyterian | Pittsburgh | Pennsylvania | 15213 | — |
| Children's Hospital of Pittsburgh of UPMC | Pittsburgh | Pennsylvania | 15224 | — |
| UPMC Hillman Cancer Center | Pittsburgh | Pennsylvania | 15232 | — |
| Hasbro Children's Hospital | Providence | Rhode Island | 02903 | — |
| Rhode Island Hospital-Pharmacy Service | Providence | Rhode Island | 02903 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| The Miriam Hospital | Providence | Rhode Island | 02906 | — |
| Medical University of South Carolina - Hospital | Charleston | South Carolina | 29425 | — |
| Medical University of South Carolina Lifespan Comprehensive Sickle Cell Center | Charleston | South Carolina | 29425 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| MUSC Investigational Drug Services | Charleston | South Carolina | 29425 | — |
| Cook Children's Hematology and Oncology Center | Fort Worth | Texas | 76104 | — |
| Cook Children's Medical Center | Fort Worth | Texas | 76104 | — |
| Cook Children's Hematology and Oncology Center-Grapevine | Grapevine | Texas | 76051 | — |
| Texas Children's Hospital - Clinical Research Center | Houston | Texas | 77030 | — |
| Texas Children´s Hospital | Houston | Texas | 77030 | — |
| University of Texas Medical School | Houston | Texas | 77030 | — |
| Primary Children's Hospital | Salt Lake City | Utah | 84113 | — |
| Main Hospital - Virginia Commonwealth University | Richmond | Virginia | 23298 | — |
| Virginia Commonwealth University-Investigational Drug Services | Richmond | Virginia | 23298 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23298 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 16 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02187003, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 10, 2025 · Synced Sep 2, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02187003 live on ClinicalTrials.gov.