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Completed Phase 1 Interventional

Safety Study of SGN-CD70A in Cancer Patients

ClinicalTrials.gov ID: NCT02216890

Public ClinicalTrials.gov record NCT02216890. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 1, 2026, 2:25 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1 Trial of SGN-CD70A in Patients With CD70-Positive Malignancies

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study will examine the safety profile of SGN-CD70A. The study will test increasing doses of SGN-CD70A given every 3 weeks (or an alternate dosing schedule up to every 6 weeks) to small groups of patients. The goal is to find the highest dose of SGN-CD70A that can be given to patients without causing unacceptable side effects. The pharmacokinetics and antitumor activity of SGN-CD70A will also be evaluated.

Study identification

NCT ID
NCT02216890
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Seagen Inc.
Industry
Enrollment
38 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 2014 (Actual)
Primary completion
Feb 15, 2017 (Actual)
Completion
Feb 15, 2017 (Actual)
Last update posted
Apr 19, 2018

2014 – 2017

United States locations

U.S. sites
17
U.S. states
12
U.S. cities
17
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35294 —
City of Hope National Medical Center Duarte California 91010-3000 —
Cardinal Bernardin Cancer Center / Loyola University Medical Center Maywood Illinois 60153 —
University of Michigan Comprehensive Cancer Center Ann Arbor Michigan 48109 —
Karmanos Cancer Institute / Wayne State University Detroit Michigan 48201 —
Comprehensive Cancer Centers of Nevada Las Vegas Nevada 89169 —
James P. Wilmot Cancer Center / University of Rochester Medical Center Rochester New York 14642 —
UNC Lineberger Comprehensive Cancer Center / University of North Carolina Chapel Hill North Carolina 27599 —
University of Cincinnati Cancer Institute Cincinnati Ohio 45267 —
Case Western Reserve University / University Hospitals Case Medical Center Cleveland Ohio 44106 —
University of Pennsylvania / Perelman Center for Advanced Medicine Philadelphia Pennsylvania 19104 —
Medical University of South Carolina/Hollings Cancer Center Charleston South Carolina 29425 —
Texas Oncology - Austin Midtown Austin Texas 78705 —
Methodist Cancer Center Houston Texas 77030 —
University of Texas Health Science Center at San Antonio San Antonio Texas 78229 —
Seattle Cancer Care Alliance / University of Washington Seattle Washington 98109-1023 —
Northwest Cancer Specialists, P.C. Vancouver Washington 98684 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02216890, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 19, 2018 · Synced Oct 1, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02216890 live on ClinicalTrials.gov.

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