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Completed Phase 2 Interventional Results available

Safety Evaluation of 3K3A-APC in Ischemic Stroke

ClinicalTrials.gov ID: NCT02222714

Public ClinicalTrials.gov record NCT02222714. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 12:45 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multi-center, Phase 2 Study Using a Continual Reassessment Method to Determine the Safety and Tolerability of 3K3A-APC in Combination With tPA, Mechanical Thrombectomy or Both in Moderate to Severe Acute Ischemic Stroke

Study identification

NCT ID
NCT02222714
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
ZZ Biotech, LLC
Industry
Enrollment
110 participants

Conditions and interventions

Interventions

  • 3K3A-APC Biological
  • Placebo Drug

Biological · Drug

Eligibility (public fields only)

Age range
18 Years to 90 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 30, 2014
Primary completion
Apr 17, 2017
Completion
Jun 28, 2017
Last update posted
Nov 7, 2018

2014 – 2017

United States locations

U.S. sites
15
U.S. states
12
U.S. cities
15
Facility City State ZIP Site status
Stroke Center Los Angeles California 90048
Stroke Center Chicago Illinois 60611
Stroke Center Kansas City Kansas 66160
Stroke Center Boston Massachusetts 02114
Stroke Center St Louis Missouri 63110
Stroke Center Buffalo New York 14209
Stroke Center New York New York 10032
Stroke Center Rochester New York 14642
Stroke Center Cincinnati Ohio 45208
Stroke Center Columbus Ohio 43210
Stroke Center Pittsburgh Pennsylvania 15213
Stroke Center Nashville Tennessee 37232
Stroke Center Dallas Texas 75390
Stroke Center Salt Lake City Utah 84132
Stroke Center Charlottesville Virginia 22904

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02222714, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 7, 2018 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02222714 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →