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Terminated Phase 1Phase 2 Interventional

Study of the Intravitreal Implantation of NT-503-3 Encapsulated Cell Technology (ECT) for the Treatment of Recurrent Choroidal Neovascularization (CNV) Secondary to Age-related Macular Degeneration (AMD)

ClinicalTrials.gov ID: NCT02228304

Public ClinicalTrials.gov record NCT02228304. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 9:55 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multi-Center, Two-Stage, Open-Label Phase I and Randomized, Active Controlled, Masked Phase II Study to Evaluate the Safety and Efficacy of Intravitreal Implantation of NT-503-3 Encapsulated Cell Technology Compared With Eylea for the Treatment of Recurrent CNV Secondary to AMD

Study identification

NCT ID
NCT02228304
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Neurotech Pharmaceuticals
Industry
Enrollment
42 participants

Conditions and interventions

Interventions

  • NT-503-3 ECT implantation Drug
  • Eylea® injected intravitreally administered every 8 weeks Drug

Drug

Eligibility (public fields only)

Age range
50 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 31, 2014
Primary completion
Mar 31, 2016
Completion
Mar 31, 2016
Last update posted
Jul 17, 2022

2014 – 2016

United States locations

U.S. sites
32
U.S. states
21
U.S. cities
31
Facility City State ZIP Site status
Associated Retina Consultants, Ltd. Phoenix Arizona 85020
Retina-Vitreous Associates Medical Group Beverly Hills California 90211
University of California, Irvine, The Gavin Herbert Eye Institute Irvine California 92697
Jacobs Retina Center at UCSD La Jolla California 92093
Colorado Retina Associates Golden Colorado 80401
Retina Health Center Fort Myers Florida 33907
National Ophthalmic Research Institute Fort Myers Florida 33912
Center for Retina and Macular Disease Winter Haven Florida 33880
Southeast Retina Center, PC Augusta Georgia 30909
Georgina Retina, P.C. Marietta Georgia 30060
Illinois Retina Associates, S.C. Joliet Illinois 60435
Illinois Retina Associates Oak Park Illinois 60304
Retina Associates of Kentucky Lexington Kentucky 40509
The Retina Group of Washington Chevy Chase Maryland 20815
Cumberland Valley Retina Consultants, PC Hagerstown Maryland 21740
Ophthalmic Consultants of Boston Boston Massachusetts 02114
University of Michigan, Kellogg Eye Center Ann Arbor Michigan 48105
William Beaumont Hospital-Ophthalmology Research Royal Oak Michigan 48073
Lifelong Vision Foundation Chesterfield Missouri 63017
Sierra Eye Associates Reno Nevada 89502
Retina Center of New Jersey, LLC Bloomfield New Jersey 07003
NJ Retina New Brunswick New Jersey 08901
Western Carolina Retinal Associates Asheville North Carolina 28803
Wake Forest Baptist Health Eye Center Winston-Salem North Carolina 27157
Cleveland Clinic Cleveland Ohio 44195
Retina Northwest, PC Portland Oregon 97210
Mid Atlantic Retina Philadelphia Pennsylvania 19107
Palmetto Retina Center, LLC Florence South Carolina 29501
Black Hills Regional Eye Institute Rapid City South Dakota 57701
Valley Retina Institute, PA McAllen Texas 78503
Medical Center Ophthalmology Associates San Antonio Texas 78240
Medical College of Wisconsin Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02228304, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 17, 2022 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02228304 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →