Efficacy and Safety Study of CVT-301 In Parkinson's Disease Patients With OFF Episodes
Public ClinicalTrials.gov record NCT02240030. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Investigating the Efficacy and Safety of CVT 301 (Levodopa Inhalation Powder) in Parkinson's Disease Patients With Motor Response Fluctuations (OFF Phenomena) (SPAN-PD™)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This randomized, multicenter, placebo-controlled, double-blind study will evaluate the efficacy and safety of inhaled CVT 301 compared with placebo in PD patients experiencing motor response fluctuations (OFF phenomena) as an outpatient (i.e., at home) and in the clinic. Patients who successfully complete this study will be eligible to enroll into a 12 month treatment extension (CVT-301-004E) study.
Study identification
- NCT ID
- NCT02240030
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 351 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 30 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 2014 (Type not available)
- Primary completion
- Dec 2016 (Actual)
- Completion
- Dec 2016 (Actual)
- Last update posted
- May 28, 2019
2014 – 2016
United States locations
- U.S. sites
- 55
- U.S. states
- 24
- U.S. cities
- 50
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Acorda Site #5020 | Scottsdale | Arizona | 85259 | — |
| Acorda Site #5042 | Fresno | California | 93710 | — |
| Acorda Site #5064 | Fullerton | California | 92835 | — |
| Acorda Site #5035 | Loma Linda | California | 92354 | — |
| Acorda Site #5027 | Long Beach | California | 90806 | — |
| Acorda Site #5037 | Los Angeles | California | 90033 | — |
| Acorda Site #5070 | Pasadena | California | 91105 | — |
| Acorda Site #5047 | Reseda | California | 91335 | — |
| Acorda Site #5068 | Santa Ana | California | 92705 | — |
| Acorda Site #5069 | Torrance | California | 90505 | — |
| Acorda Site #5052 | Washington D.C. | District of Columbia | 20007 | — |
| Acorda Site #5046 | Atlantis | Florida | 33462 | — |
| Acorda Site #5053 | Aventura | Florida | 33180 | — |
| Acorda Site #5013 | Boca Raton | Florida | 33486 | — |
| Acorda Site #5016 | Jacksonville | Florida | 32209 | — |
| Acorda Site #5071 | Maitland | Florida | 32751 | — |
| Acorda Site #5044 | Orlando | Florida | 32806 | — |
| Acorda Site #5060 | Palm Beach Gardens | Florida | 33410 | — |
| Acorda Site #5001 | Port Charlotte | Florida | 33952 | — |
| Acorda Site #5065 | St. Petersburg | Florida | 33713 | — |
| Acorda Site #5012 | Tampa | Florida | 33613 | — |
| Acorda Site #5040 | Atlanta | Georgia | 30329 | — |
| Acorda Site #5025 | Chicago | Illinois | 60611 | — |
| Acorda Site #5030 | Chicago | Illinois | 60612 | — |
| Acorda Site #5011 | Elk Grove Village | Illinois | 60007 | — |
| Acorda Site #5003 | Kansas City | Kansas | 66160 | — |
| Acorda Site #5067 | Baton Rouge | Louisiana | 70810 | — |
| Acorda Site #5057 | Baltimore | Maryland | 21201 | — |
| Acorda Site #5056 | Boston | Massachusetts | 02114 | — |
| Acorda Site #5018 | Boston | Massachusetts | 02118 | — |
| Acorda Site #5002 | Bingham Farms | Michigan | 48025 | — |
| Acorda Site #5014 | West Bloomfield | Michigan | 48322 | — |
| Acorda Site #5041 | Golden Valley | Minnesota | 55427 | — |
| Acorda Site #5006 | St Louis | Missouri | 63110 | — |
| Acorda Site #5023 | Las Vegas | Nevada | 89102 | — |
| Acorda Site #5028 | Albany | New York | 12208 | — |
| Acorda Site #5039 | Brooklyn | New York | 11203 | — |
| Acorda Site #5031 | New York | New York | 10016 | — |
| Acorda Site #5032 | New York | New York | 10029 | — |
| Acorda Site #5004 | New York | New York | 10032 | — |
| Acorda Site #5038 | Syracuse | New York | 13210 | — |
| Acorda Site #5048 | Charlotte | North Carolina | 28204 | — |
| Acorda Site #5005 | Cleveland | Ohio | 44195 | — |
| Acorda Site #5050 | Norwood | Ohio | 45212 | — |
| Acorda Site #5062 | Portland | Oregon | 97239 | — |
| Acorda Site #5036 | Allentown | Pennsylvania | 18103 | — |
| Acorda Site #5010 | Philadelphia | Pennsylvania | 19107 | — |
| Acorda Site #5058 | Willow Grove | Pennsylvania | 19090 | — |
| Acorda Site #5022 | Charleston | South Carolina | 29425 | — |
| Acorda Site #5029 | Nashville | Tennessee | 372322551 | — |
| Acorda Site #5019 | Houston | Texas | 77030 | — |
| Acorda Site #5045 | Houston | Texas | 77030 | — |
| Acorda Site #5049 | Henrico | Virginia | 23226 | — |
| Acorda Site #5059 | Virginia Beach | Virginia | 23456 | — |
| Acorda Site #5051 | Kirkland | Washington | 98034 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 19 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02240030, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 28, 2019 · Synced Oct 26, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02240030 live on ClinicalTrials.gov.