Linagliptin as Add on to Basal Insulin in the Elderly
Public ClinicalTrials.gov record NCT02240680. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A 24 Week Randomized, Double-blind, Placebo-controlled, Parallel Group, Efficacy and Safety Trial of Once Daily Linagliptin, 5 Milligrams Orally, as Add on to Basal Insulin in Elderly Type 2 Diabetes Mellitus Patients With Insufficient Glycaemic Control
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To investigate the efficacy, safety, and tolerability of linagliptin 5 milligrams once a day compared to placebo as as add-on therapy for 24 weeks to stable basal insulin treatment in elderly patients, 60 years of age and older, with Type 2 Diabetes Mellitus and insufficient glycaemic control.Stable background therapy of metformin and/or alpha-glucosidase inhibitors is also allowed. In addition, this trial will assess if linagliptin reduces the risk of hypoglycaemia when added to background basal insulin therapy. The treatment duration of this trial (24 weeks) will enable assessment of the clinically relevant endpoint of a decrease in glycosylated Haemoglobin, a well-accepted measurement of chronic glycaemic control.
Study identification
- NCT ID
- NCT02240680
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 302 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 60 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 23, 2014 (Actual)
- Primary completion
- Apr 18, 2017 (Actual)
- Completion
- Apr 25, 2017 (Actual)
- Last update posted
- Jul 3, 2018
2014 – 2017
United States locations
- U.S. sites
- 38
- U.S. states
- 18
- U.S. cities
- 35
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Syed Research Consultants, LLC | Sheffield | Alabama | 35660 | — |
| Precision Research Institute, LLC | Chula Vista | California | 91910 | — |
| Aurora Care Clinic, LLC | Costa Mesa | California | 92627 | — |
| Prime Care Clinical Research | Laguna Hills | California | 92653 | — |
| Torrance Clinical Research Institute Inc. | Lomita | California | 90717 | — |
| Internal Medicine of the Rockies | Colorado Springs | Colorado | 80910 | — |
| Cohen Medical Research Associates, LLC | Delray Beach | Florida | 33446 | — |
| Riverside Clinical Research | Edgewater | Florida | 32132 | — |
| Clinical Research of Hollywood | Hollywood | Florida | 33024 | — |
| East Coast Institute for Research LLC at NE FL Endo & Diabetes | Jacksonville | Florida | 32204 | — |
| Solutions Through Advanced Research, Inc. | Jacksonville | Florida | 32258 | — |
| Baptist Diabetes Associates, PA | Miami | Florida | 33156 | — |
| International Research Associates | Miami | Florida | 33183 | — |
| Panax Clinical Research | Miami Lakes | Florida | 33014 | — |
| South Florida Research Solutions, LLC | Pembroke Pines | Florida | 33026 | — |
| Georgia Clinical Research, LLC | Snellville | Georgia | 30078 | — |
| Midwest Endocrinology | Crystal Lake | Illinois | 60012 | — |
| American Health Network | Avon | Indiana | 46123 | — |
| Accent Clinical Trials | Las Vegas | Nevada | 89052 | — |
| Clinical Research of South Nevada | Las Vegas | Nevada | 89121 | — |
| Manhattan Medical Research Practice PLLC | New York | New York | 10016 | — |
| Family Practice Center of Wadsworth, Inc. | Wadsworth | Ohio | 44281 | — |
| Clinical Research Associates of Central Pennsylvania | Altoona | Pennsylvania | 16602 | — |
| Fleetwood Clinical Research | Fleetwood | Pennsylvania | 19522 | — |
| Preferred Primary Care Phys | Uniontown | Pennsylvania | 15401 | — |
| TLM Medical Services, LLC | Columbia | South Carolina | 29204 | — |
| Advanced Research Associates | Hodges | South Carolina | 29653 | — |
| Holston Medical Group | Kingsport | Tennessee | 37660 | — |
| Arlington Family Research Center, Inc. | Arlington | Texas | 76012 | — |
| Renaissance Clinical Research and Hypertension of Texas | Dallas | Texas | 75234 | — |
| Diabetes and Thyroid Center of Fort Worth | Fort Worth | Texas | 76132 | — |
| Houston Clinical Research Associates | Houston | Texas | 77090 | — |
| Science Advancing Medicine Clinical Research Center | San Antonio | Texas | 78229 | — |
| Office of Dr. Val R. Hansen | Bountiful | Utah | 84010 | — |
| Millennium Clinical Trials LLC | Arlington | Virginia | 22203 | — |
| York Clinical Research, LLC | Norfolk | Virginia | 23510 | — |
| Rowan Research, Inc. | Spokane | Washington | 99218 | — |
| Family Medical Clinic | Milwaukee | Wisconsin | 53216 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 107 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02240680, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 3, 2018 · Synced Oct 28, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02240680 live on ClinicalTrials.gov.