Open-Label Study of Leuco-methylthioninium Bis(Hydromethanesulfonate) (LMTM) in Subjects With Alzheimer's Disease or Behavioral Variant Frontotemporal Dementia (bvFTD)
Public ClinicalTrials.gov record NCT02245568. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-Label, Extension Study of the Effects of LMTM in Subjects With Alzheimer's Disease or Behavioral Variant Frontotemporal Dementia (bvFTD)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to provide subjects who have completed participation in a Phase 2 or Phase 3 trial of LMTM continued access to therapy and to evaluate the long-term safety of LMTM.
Study identification
- NCT ID
- NCT02245568
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 913 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- Not listed
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 2014 (Actual)
- Primary completion
- May 2017 (Actual)
- Completion
- May 2017 (Actual)
- Last update posted
- May 24, 2023
2014 – 2017
United States locations
- U.S. sites
- 57
- U.S. states
- 23
- U.S. cities
- 51
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Xenoscience, Inc / 21st Century Neurology | Phoenix | Arizona | 85004 | — |
| Southern California Research, LLC | Fountain Valley | California | 92708 | — |
| Feldman, Robert MD | Laguna Hills | California | 92653 | — |
| Collaborative Neuroscience Network | Long Beach | California | 90806 | — |
| The Shankle Clinic | Newport Beach | California | 92663 | — |
| Neuro-Therapeutics, Inc. | Pasadena | California | 91105 | — |
| Pacific Research Network | San Diego | California | 92103 | — |
| San Francisco Clinical Research Center | San Francisco | California | 94118 | — |
| Memory and Aging Centre | San Francisco | California | 94158 | — |
| Schuster Medical Research Institute | Sherman Oaks | California | 91403 | — |
| Mile High Research Center | Denver | Colorado | 80218 | — |
| Institute for Neurodegenerative Disorders | New Haven | Connecticut | 06510 | — |
| Yale University School of Medicine | New Haven | Connecticut | 06510 | — |
| Coastal Connecticut Research, LLC | New London | Connecticut | 06320 | — |
| JEM Research | Atlantis | Florida | 33462 | — |
| Bradenton Research Center | Bradenton | Florida | 34205 | — |
| Meridien Research | Brooksville | Florida | 34601 | — |
| Brain Matters Research | Delray Beach | Florida | 33445 | — |
| MD Clinical | Hallandale | Florida | 33009 | — |
| Mayo Clinic | Jacksonville | Florida | 32224 | — |
| CNS Healthcare, Inc | Jacksonville | Florida | 32256 | — |
| Miami Research Associates | Miami | Florida | 33143 | — |
| Compass Research, LLC | Orlando | Florida | 32806 | — |
| The Roskamp Institute, Inc. | Sarasota | Florida | 34243 | — |
| Axiom Clinical Research of Florida | Tampa | Florida | 33609 | — |
| University of South Florida | Tampa | Florida | 33613 | — |
| Compass Research, LLC - North Clinic | The Villages | Florida | 32162 | — |
| iResearch Atlanta | Decatur | Georgia | 30030 | — |
| Neurostudies.net | Decatur | Georgia | 30033 | — |
| Alexian Brothers Neurosciences Institute | Elk Grove Village | Illinois | 60007 | — |
| Ruan Neurology Clinic and Research Center | Des Moines | Iowa | 50314 | — |
| ActivMed Practices & Research | Methuen | Massachusetts | 01844 | — |
| Mayo Clinic, Alzheimer's Disease Research Center | Rochester | Minnesota | 55905 | — |
| Neurological Research Center - Hattiesburg Clinic | Hattiesburg | Mississippi | 39401 | — |
| Millennium Psychiatric Associates | Creve Coeur | Missouri | 63141 | — |
| Memory Enhancement Center of America, Inc | Eatontown | New Jersey | 07724 | — |
| The Atlantic Neuroscience Institute | Springfield | New Jersey | 07801 | — |
| Advanced Memory Research Institute of NJ PC | Toms River | New Jersey | 08757 | — |
| Neurological Associates of Albany, P. C. | Albany | New York | 12208 | — |
| SPRI | Brooklyn | New York | 11235 | — |
| Columbia University Taub Institute | New York | New York | 10032 | — |
| Research Foundation for Mental Hygiene, Inc. | Orangeburg | New York | 10962 | — |
| UNC Department of Neurology, Physicians Office Building | Chapel Hill | North Carolina | 27599 | — |
| Clinical Trials of America, Inc | Winston-Salem | North Carolina | 27103 | — |
| Neurobehavioral Clinical Research | Canton | Ohio | 44718 | — |
| University Hospitals Case Medical Center, Neurology Clinical Trials Unit | Cleveland | Ohio | 44106 | — |
| Rivus Wellness and Research Institute | Oklahoma City | Oklahoma | 73112 | — |
| The Clinical Trial Center, LLC | Jenkintown | Pennsylvania | 19046 | — |
| Hospital of the University of Pennsylvania, Department of Neurology | Philadelphia | Pennsylvania | 19104 | — |
| RI Hospital | Providence | Rhode Island | 02903 | — |
| Neurology Clinic, P.C. | Cordova | Tennessee | 38018 | — |
| Clinical Neuroscience Solutions CNS Healthcare | Memphis | Tennessee | 38119 | — |
| FutureSearch Trials of Neurology | Austin | Texas | 78731 | — |
| Senior Adults Specialty Research, Inc. | Austin | Texas | 78757 | — |
| FutureSearch Trials of Dallas, LP | Dallas | Texas | 75231 | — |
| University of Virginia Adult Neurology, Primary Care Center | Charlottesville | Virginia | 22903 | — |
| Independent Psychiatric Consultants | Waukesha | Wisconsin | 53188 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 78 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02245568, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 24, 2023 · Synced Oct 27, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02245568 live on ClinicalTrials.gov.