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Terminated Phase 3 Interventional Results available

A Study Investigating the Efficacy and Safety of Lampalizumab Intravitreal Injections in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration

ClinicalTrials.gov ID: NCT02247479

Public ClinicalTrials.gov record NCT02247479. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 2:38 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III, Multicenter, Randomized, Double-Masked, Sham-Controlled Study to Assess the Efficacy and Safety of Lampalizumab Administered Intravitreally to Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study is a Phase III, double-masked, multicenter, randomized, sham injection-controlled study evaluating the efficacy and safety of lampalizumab administered by intravitreal injections in participants with geographic atrophy (GA) secondary to age-related macular degeneration (AMD).

Study identification

NCT ID
NCT02247479
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
906 participants

Conditions and interventions

Interventions

Drug · Other

Eligibility (public fields only)

Age range
50 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 17, 2014
Primary completion
Jan 28, 2018
Completion
Jan 28, 2018
Last update posted
Jun 25, 2019

2014 – 2018

United States locations

U.S. sites
76
U.S. states
30
U.S. cities
69
Facility City State ZIP Site status
Uni of Alabama At Birmingham Clinical Research Unit Birmingham Alabama 35233
Retinal Research Institute, LLC Phoenix Arizona 85014
Retina Centers P.C. Tucson Arizona 85704
California Retina Consultants Bakersfield California 93309
Retina-Vitreous Associates Medical Group Beverly Hills California 90211
The Gavin Herbert Eye Institute - UC, Irvine Irvine California 92697-4375
Jules Stein Eye Institute/ UCLA Los Angeles California 90095-7000
East Bay Retina Consultants Oakland California 94609
Southern CA Desert Retina Cons Palm Desert California 92211
W Coast Retina Med Group Inc San Francisco California 94107
UCSF; Ophthalmology San Francisco California 94143
Orange County Retina Med Group Santa Ana California 92705
California Retina Consultants Santa Barbara California 93103
Florida Eye Microsurgical Inst Boynton Beach Florida 33426
National Ophthalmic Research Institute Fort Myers Florida 33912
Florida Eye Associates Melbourne Florida 32901
Retina Care Specialists Palm Beach Gardens Florida 33410
Bascom Palmer Eye Institute Palm Beach Gardens Florida 33418
Retina Specialty Institute Pensacola Florida 32503
Fort Lauderdale Eye Institute Plantation Florida 33324
Retina Vitreous Assoc of FL St. Petersburg Florida 33711
Southern Vitreoretinal Assoc Tallahassee Florida 32308
Retina Associates of Florida, LLC Tampa Florida 33609
Southeast Retina Center Augusta Georgia 30909
Georgia Retina PC Marietta Georgia 30060
Retina Consultants of Hawaii ‘Aiea Hawaii 96701
Northwestern Medical Group/Northwestern University Chicago Illinois 60611
University Retina and Macula Associates, PC Oak Forest Illinois 60452
Midwest Eye Institute Northside Indianapolis Indiana 46290
Wolfe Eye Clinic West Des Moines Iowa 50266
Retina Associates Shawnee Mission Kansas 66204
Lahey Clinic Med Ctr Lexington Kentucky 02421
Retina Associates of Kentucky Lexington Kentucky 40509
Maine Eye Center Portland Maine 04101
Retina Specialists Towson Maryland 21204
Tufts Medical Center Research Boston Massachusetts 02111
Ophthalmic Consultants of Boston Boston Massachusetts 02114
Vitreo-Retinal Associates, PC Worcester Massachusetts 01605
Vitreo-Retinal Associates Grand Rapids Michigan 49546
Specialty Eye Institute Jackson Michigan 49202
Assoc Retinal Consultants PC Royal Oak Michigan 48073
Retina Consultants of Michigan Southfield Michigan 48034
Eye Surgical Associates Lincoln Nebraska 68506
Retina Consultants of Nevada Las Vegas Nevada 89123
Retina Center of New Jersey Bloomfield New Jersey 07003
New Jersey Retina Research Foundation Edison New Jersey 08820
Delaware Valley Retina Assoc Lawrenceville New Jersey 08648
Long Is. Vitreoretinal Consult Hauppauge New York 11788
Opthalmic Consultants of LI Lynbrook New York 11563
New York Eye & Ear Infirmary New York New York 10003
Retina Consultants of Western New York Orchard Park New York 14127
Retina Vit Surgeons/Central NY Syracuse New York 13224
Western Carolina Retinal Associate PA Asheville North Carolina 28803
Wake Forest Baptist Health Eye Centre Winston-Salem North Carolina 27157
Retina Assoc of Cleveland Inc Beachwood Ohio 44122
Cleveland Clinic Foundation; Cole Eye Institute Cleveland Ohio 44195
Retina Vitreous Consultants Monroeville Pennsylvania 15146
Associates in Ophthalmology West Mifflin Pennsylvania 15122
Charleston Neuroscience Inst Ladson South Carolina 29456
Tennessee Retina PC. Nashville Tennessee 37203
Vanderbilt Nashville Tennessee 37232
Retina Res Institute of Texas Abilene Texas 79606
Texas Retina Associates Arlington Texas 76012
Austin Retina Associates Austin Texas 78705
Retina Research Center Austin Texas 78705
UT Southwestern MC at Dallas Dallas Texas 75390
Valley Retina Institute P.A. McAllen Texas 78503
Strategic Clinical Research Group, LLC Willow Park Texas 76087
Retina Associates of Utah Salt Lake City Utah 84107
Eye Surgeons of Richmond Inc. dba Virginia Eye Institute Richmond Virginia 23226
Retina Institute of Virginia Richmond Virginia 23235
Virginia Retina Center Warrenton Virginia 20186
Retina Center Northwest Silverdale Washington 98383
Spokane Eye Clinical Research Spokane Washington 99204
West Virginia University Eye Institute Morgantown West Virginia 26506
University of Wisconsin Madison Wisconsin 53792

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 69 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02247479, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 25, 2019 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02247479 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →