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Terminated Phase 3 Interventional Results available

A Study Investigating the Efficacy and Safety of Lampalizumab Intravitreal Injections in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration

ClinicalTrials.gov ID: NCT02247479

Public ClinicalTrials.gov record NCT02247479. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 19, 2026, 9:07 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III, Multicenter, Randomized, Double-Masked, Sham-Controlled Study to Assess the Efficacy and Safety of Lampalizumab Administered Intravitreally to Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study is a Phase III, double-masked, multicenter, randomized, sham injection-controlled study evaluating the efficacy and safety of lampalizumab administered by intravitreal injections in participants with geographic atrophy (GA) secondary to age-related macular degeneration (AMD).

Study identification

NCT ID
NCT02247479
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
906 participants

Conditions and interventions

Interventions

Drug · Other

Eligibility (public fields only)

Age range
50 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 18, 2014 (Actual)
Primary completion
Jan 29, 2018 (Actual)
Completion
Jan 29, 2018 (Actual)
Last update posted
Jun 26, 2019

2014 – 2018

United States locations

U.S. sites
76
U.S. states
30
U.S. cities
69
Facility City State ZIP Site status
Uni of Alabama At Birmingham Clinical Research Unit Birmingham Alabama 35233 —
Retinal Research Institute, LLC Phoenix Arizona 85014 —
Retina Centers P.C. Tucson Arizona 85704 —
California Retina Consultants Bakersfield California 93309 —
Retina-Vitreous Associates Medical Group Beverly Hills California 90211 —
The Gavin Herbert Eye Institute - UC, Irvine Irvine California 92697-4375 —
Jules Stein Eye Institute/ UCLA Los Angeles California 90095-7000 —
East Bay Retina Consultants Oakland California 94609 —
Southern CA Desert Retina Cons Palm Desert California 92211 —
W Coast Retina Med Group Inc San Francisco California 94107 —
UCSF; Ophthalmology San Francisco California 94143 —
Orange County Retina Med Group Santa Ana California 92705 —
California Retina Consultants Santa Barbara California 93103 —
Florida Eye Microsurgical Inst Boynton Beach Florida 33426 —
National Ophthalmic Research Institute Fort Myers Florida 33912 —
Florida Eye Associates Melbourne Florida 32901 —
Retina Care Specialists Palm Beach Gardens Florida 33410 —
Bascom Palmer Eye Institute Palm Beach Gardens Florida 33418 —
Retina Specialty Institute Pensacola Florida 32503 —
Fort Lauderdale Eye Institute Plantation Florida 33324 —
Retina Vitreous Assoc of FL St. Petersburg Florida 33711 —
Southern Vitreoretinal Assoc Tallahassee Florida 32308 —
Retina Associates of Florida, LLC Tampa Florida 33609 —
Southeast Retina Center Augusta Georgia 30909 —
Georgia Retina PC Marietta Georgia 30060 —
Retina Consultants of Hawaii ‘Aiea Hawaii 96701 —
Northwestern Medical Group/Northwestern University Chicago Illinois 60611 —
University Retina and Macula Associates, PC Oak Forest Illinois 60452 —
Midwest Eye Institute Northside Indianapolis Indiana 46290 —
Wolfe Eye Clinic West Des Moines Iowa 50266 —
Retina Associates Shawnee Mission Kansas 66204 —
Lahey Clinic Med Ctr Lexington Kentucky 02421 —
Retina Associates of Kentucky Lexington Kentucky 40509 —
Maine Eye Center Portland Maine 04101 —
Retina Specialists Towson Maryland 21204 —
Tufts Medical Center Research Boston Massachusetts 02111 —
Ophthalmic Consultants of Boston Boston Massachusetts 02114 —
Vitreo-Retinal Associates, PC Worcester Massachusetts 01605 —
Vitreo-Retinal Associates Grand Rapids Michigan 49546 —
Specialty Eye Institute Jackson Michigan 49202 —
Assoc Retinal Consultants PC Royal Oak Michigan 48073 —
Retina Consultants of Michigan Southfield Michigan 48034 —
Eye Surgical Associates Lincoln Nebraska 68506 —
Retina Consultants of Nevada Las Vegas Nevada 89123 —
Retina Center of New Jersey Bloomfield New Jersey 07003 —
New Jersey Retina Research Foundation Edison New Jersey 08820 —
Delaware Valley Retina Assoc Lawrenceville New Jersey 08648 —
Long Is. Vitreoretinal Consult Hauppauge New York 11788 —
Opthalmic Consultants of LI Lynbrook New York 11563 —
New York Eye & Ear Infirmary New York New York 10003 —
Retina Consultants of Western New York Orchard Park New York 14127 —
Retina Vit Surgeons/Central NY Syracuse New York 13224 —
Western Carolina Retinal Associate PA Asheville North Carolina 28803 —
Wake Forest Baptist Health Eye Centre Winston-Salem North Carolina 27157 —
Retina Assoc of Cleveland Inc Beachwood Ohio 44122 —
Cleveland Clinic Foundation; Cole Eye Institute Cleveland Ohio 44195 —
Retina Vitreous Consultants Monroeville Pennsylvania 15146 —
Associates in Ophthalmology West Mifflin Pennsylvania 15122 —
Charleston Neuroscience Inst Ladson South Carolina 29456 —
Tennessee Retina PC. Nashville Tennessee 37203 —
Vanderbilt Nashville Tennessee 37232 —
Retina Res Institute of Texas Abilene Texas 79606 —
Texas Retina Associates Arlington Texas 76012 —
Austin Retina Associates Austin Texas 78705 —
Retina Research Center Austin Texas 78705 —
UT Southwestern MC at Dallas Dallas Texas 75390 —
Valley Retina Institute P.A. McAllen Texas 78503 —
Strategic Clinical Research Group, LLC Willow Park Texas 76087 —
Retina Associates of Utah Salt Lake City Utah 84107 —
Eye Surgeons of Richmond Inc. dba Virginia Eye Institute Richmond Virginia 23226 —
Retina Institute of Virginia Richmond Virginia 23235 —
Virginia Retina Center Warrenton Virginia 20186 —
Retina Center Northwest Silverdale Washington 98383 —
Spokane Eye Clinical Research Spokane Washington 99204 —
West Virginia University Eye Institute Morgantown West Virginia 26506 —
University of Wisconsin Madison Wisconsin 53792 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 69 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02247479, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 26, 2019 · Synced Oct 19, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02247479 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →