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Terminated Phase 3 Interventional Results available

A Study Investigating the Safety and Efficacy of Lampalizumab Intravitreal Injections in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration

ClinicalTrials.gov ID: NCT02247531

Public ClinicalTrials.gov record NCT02247531. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 25, 2026, 1:25 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III, Multicenter, Randomized, Double-Masked, Sham-Controlled Study to Assess the Efficacy and Safety of Lampalizumab Administered Intravitreally to Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study is a Phase III, double-masked, multicenter, randomized, sham injection-controlled study evaluating the efficacy and safety of lampalizumab administered by intravitreal injections in participants with geographic atrophy (GA) secondary to age-related macular degeneration (AMD).

Study identification

NCT ID
NCT02247531
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
975 participants

Conditions and interventions

Interventions

Drug · Other

Eligibility (public fields only)

Age range
50 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 6, 2014 (Actual)
Primary completion
Jan 23, 2018 (Actual)
Completion
Jan 23, 2018 (Actual)
Last update posted
Oct 15, 2019

2014 – 2018

United States locations

U.S. sites
67
U.S. states
28
U.S. cities
63
Facility City State ZIP Site status
Associated Retina Consultants Phoenix Arizona 85020 —
Retina Associates Southwest PC Tucson Arizona 85750 —
Retina Consultants of Orange County Fullerton California 92835 —
UCSD Shiley Eye Center La Jolla California 92093-0946 —
Jules Stein Eye Institute/ UCLA Los Angeles California 90095-7000 —
N CA Retina Vitreous Assoc Mountain View California 94040 —
Byers Eye Insitute at Stanford Palo Alto California 94303 —
Retina Consultants, San Diego Poway California 92064 —
University of California, Davis, Eye Center Sacramento California 95817 —
Retinal Consultants Med Group Sacramento California 95841 —
California Retina Consultants Santa Barbara California 93103 —
Bay Area Retina Associates Walnut Creek California 94598 —
University of Colorado Aurora Colorado 80045 —
Retina Consultants of Southern Colorado Springs Colorado 80909 —
Colorado Retina Associates, PC Golden Colorado 80401 —
New England Retina Associates Hamden Connecticut 06518 —
Retina Group of New England Waterford Connecticut 06385 —
Retina Group of Florida Fort Lauderdale Florida 33308 —
Retina Health Center Fort Myers Florida 33907 —
Bascom Palmer Eye Institute Naples Florida 34103 —
Retina Vitreous Assoc of FL St. Petersburg Florida 33711 —
Southern Vitreoretinal Assoc Tallahassee Florida 32308 —
University of South Florida Tampa Florida 33612 —
Emory University Atlanta Georgia 30329 —
Wolfe Eye Clinic West Des Moines Iowa 50266 —
Vitreo Retinal Consultants Wichita Kansas 67214 —
Paducah Retinal Center Paducah Kentucky 42001 —
The Retina Care Center Baltimore Maryland 21209 —
Wilmer Eye Institute Baltimore Maryland 21287 —
Retina Group of Washington Chevy Chase Maryland 20815 —
Retina Specialists Towson Maryland 21204 —
Mass Eye and Ear Infirmary Boston Massachusetts 02114 —
University of Michigan, Kellogg Eye Center Ann Arbor Michigan 48105 —
Kresge Eye Institute Detroit Michigan 48201-1423 —
Vitreoretinal Surgery Edina Minnesota 55435 —
Midwest Vision Research Foundation Chesterfield Missouri 63017 —
UNMC Truhlsen Eye Institute Omaha Nebraska 68105 —
Sierra Eye Associates Reno Nevada 89502 —
Mid Atlantic Retina - Wills Eye Hospital Cherry Hill New Jersey 08034 —
Retinal & Ophthalmic Cons PC Northfield New Jersey 08225 —
Retina Associates of NJ Teaneck New Jersey 07666 —
New York Weil Cornell Med Ctr New York New York 10021 —
Vitreous-Retina-Macula New York New York 10022 —
Retina Assoc of Western NY Rochester New York 14620 —
Western Carolina Retinal Associate PA Asheville North Carolina 28803 —
Char Eye Ear &Throat Assoc Charlotte North Carolina 28210 —
Duke University Eye Center; Vitreoretinal Durham North Carolina 27710 —
Cincinnati Eye Institute Cincinnati Ohio 45242 —
OSU Eye Physicians & Surgeons Columbus Ohio 43212 —
Retina & Vitreous Center of Southern Oregon Ashland Oregon 97520 —
Retina Northwest Portland Oregon 97221 —
Oregon HSU; Casey Eye Institute Portland Oregon 97239 —
Mid Atlantic Retina Philadelphia Pennsylvania 19107 —
Allegheny Ophthalmic & Orbital Pittsburgh Pennsylvania 15212 —
MUSC Storm eye institute Charleston South Carolina — —
Palmetto Retina Center Florence South Carolina 29501 —
Charleston Neuroscience Inst Ladson South Carolina 29456 —
Black Hills Eye Institute Rapid City South Dakota 57701 —
Southeastern Retina Associates Chattanooga Chattanooga Tennessee 37421 —
Charles Retina Institution Germantown Tennessee 38138 —
Retina Res Institute of Texas Abilene Texas 79606 —
Texas Retina Associates Dallas Texas 75231 —
Retina Consultants of Houston Houston Texas 77030 —
Scott and White Hospital Temple Texas 76504 —
Retina Consultants of Houston The Woodlands Texas 77384 —
Univ of Virginia Ophthalmology Charlottesville Virginia 22903 —
Vitreoretinal Associates of Washington Bellevue Washington 98004 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 86 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02247531, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 15, 2019 · Synced Oct 25, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02247531 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →