Study Comparing Daratumumab, Lenalidomide, and Dexamethasone With Lenalidomide and Dexamethasone in Participants With Previously Untreated Multiple Myeloma
Open the official record
This page only displays public information reproduced from the official ClinicalTrials.gov record NCT02252172. It adds no medical advice, opinions, or eligibility judgments. The official record remains the source of truth for eligibility criteria, enrollment, and contact information.
All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Study Comparing Daratumumab, Lenalidomide, and Dexamethasone (DRd) vs Lenalidomide and Dexamethasone (Rd) in Subjects With Previously Untreated Multiple Myeloma Who Are Ineligible for High Dose Therapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to compare the efficacy of daratumumab in combination with lenalidomide and dexamethasone to that of lenalidomide and dexamethasone in terms of progression-free survival (PFS) in participants with newly diagnosed multiple myeloma (a blood cancer of plasma cells) who are not candidates for high dose chemotherapy (treatment of disease, usually cancer, by chemical agents) and autologous stem cell transplant (ASCT).
Study identification
- NCT ID
- NCT02252172
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 737 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 16, 2015 (Actual)
- Primary completion
- Sep 24, 2018 (Actual)
- Completion
- Oct 2, 2024 (Actual)
- Last update posted
- Oct 20, 2025
2015 – 2024
United States locations
- U.S. sites
- 83
- U.S. states
- 32
- U.S. cities
- 83
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Birmingham | Alabama | — | — |
| Not listed | Mobile | Alabama | — | — |
| Not listed | Glendale | Arizona | — | — |
| Not listed | Berkeley | California | — | — |
| Not listed | Beverly Hills | California | — | — |
| Not listed | El Cajon | California | — | — |
| Not listed | Greenbrae | California | — | — |
| Not listed | Los Angeles | California | — | — |
| Not listed | Oceanside | California | — | — |
| Not listed | San Diego | California | — | — |
| Not listed | West Hills | California | — | — |
| Not listed | Whittier | California | — | — |
| Not listed | Denver | Colorado | — | — |
| Not listed | Fort Collins | Colorado | — | — |
| Not listed | Glenwood Springs | Colorado | — | — |
| Not listed | New Haven | Connecticut | — | — |
| Not listed | Norwalk | Connecticut | — | — |
| Not listed | Washington D.C. | District of Columbia | — | — |
| Not listed | Boca Raton | Florida | — | — |
| Not listed | Boynton Beach | Florida | — | — |
| Not listed | Fort Lauderdale | Florida | — | — |
| Not listed | Fort Myers | Florida | — | — |
| Not listed | Hollywood | Florida | — | — |
| Not listed | Jacksonville | Florida | — | — |
| Not listed | Lake City | Florida | — | — |
| Not listed | St. Petersburg | Florida | — | — |
| Not listed | Weston | Florida | — | — |
| Not listed | Atlanta | Georgia | — | — |
| Not listed | Augusta | Georgia | — | — |
| Not listed | Macon | Georgia | — | — |
| Not listed | Marietta | Georgia | — | — |
| Not listed | Chicago | Illinois | — | — |
| Not listed | Niles | Illinois | — | — |
| Not listed | Fort Wayne | Indiana | — | — |
| Not listed | Iowa City | Iowa | — | — |
| Not listed | Louisville | Kentucky | — | — |
| Not listed | Lafayette | Louisiana | — | — |
| Not listed | Marrero | Louisiana | — | — |
| Not listed | Shreveport | Louisiana | — | — |
| Not listed | Annapolis | Maryland | — | — |
| Not listed | Baltimore | Maryland | — | — |
| Not listed | Frederick | Maryland | — | — |
| Not listed | Boston | Massachusetts | — | — |
| Not listed | Detroit | Michigan | — | — |
| Not listed | Duluth | Minnesota | — | — |
| Not listed | Rochester | Minnesota | — | — |
| Not listed | Kansas City | Missouri | — | — |
| Not listed | St Louis | Missouri | — | — |
| Not listed | Omaha | Nebraska | — | — |
| Not listed | Hooksett | New Hampshire | — | — |
| Not listed | Brick | New Jersey | — | — |
| Not listed | Hackensack | New Jersey | — | — |
| Not listed | Livingston | New Jersey | — | — |
| Not listed | Plainfield | New Jersey | — | — |
| Not listed | Summit | New Jersey | — | — |
| Not listed | Mineola | New York | — | — |
| Not listed | New York | New York | — | — |
| Not listed | Rochester | New York | — | — |
| Not listed | Asheboro | North Carolina | — | — |
| Not listed | Charlotte | North Carolina | — | — |
| Not listed | Pinehurst | North Carolina | — | — |
| Not listed | Winston-Salem | North Carolina | — | — |
| Not listed | Canton | Ohio | — | — |
| Not listed | Cleveland | Ohio | — | — |
| Not listed | Columbus | Ohio | — | — |
| Not listed | Bend | Oregon | — | — |
| Not listed | Bethlehem | Pennsylvania | — | — |
| Not listed | Pittsburgh | Pennsylvania | — | — |
| Not listed | Spartanburg | South Carolina | — | — |
| Not listed | Sioux Falls | South Dakota | — | — |
| Not listed | Chattanooga | Tennessee | — | — |
| Not listed | Nashville | Tennessee | — | — |
| Not listed | Arlington | Texas | — | — |
| Not listed | Edinburg | Texas | — | — |
| Not listed | Fort Sam Houston | Texas | — | — |
| Not listed | Fort Worth | Texas | — | — |
| Not listed | Houston | Texas | — | — |
| Not listed | Plano | Texas | — | — |
| Not listed | San Antonio | Texas | — | — |
| Not listed | Ogden | Utah | — | — |
| Not listed | Seattle | Washington | — | — |
| Not listed | Spokane | Washington | — | — |
| Not listed | Tacoma | Washington | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 123 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02252172, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 20, 2025 · Synced Nov 12, 2026
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