RTA 408 Capsules in Patients With Mitochondrial Myopathy - MOTOR
Public ClinicalTrials.gov record NCT02255422. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Study of the Safety, Efficacy, and Pharmacodynamics of RTA 408 in the Treatment of Mitochondrial Myopathy (MOTOR)
Study identification
- NCT ID
- NCT02255422
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Biogen
- Industry
- Enrollment
- 53 participants
Conditions and interventions
Conditions
Interventions
- Omaveloxolone capsules, 2.5 mg Drug
- omaveloxolone capsules, 5 mg Drug
- omaveloxolone capsules, 10 mg Drug
- Placebo capsules Drug
- omaveloxolone capsules, 20 mg Drug
- omaveloxolone capsules, 40 mg Drug
- omaveloxolone capsules, 80 mg Drug
- omaveloxolone capsules, 160 mg Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 4, 2015
- Primary completion
- Nov 1, 2017
- Completion
- Nov 29, 2017
- Last update posted
- Jun 4, 2025
2015 – 2017
United States locations
- U.S. sites
- 8
- U.S. states
- 5
- U.S. cities
- 7
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UCLA | Los Angeles | California | 90095 | — |
| Mass General Hospital | Boston | Massachusetts | 02114 | — |
| Akron Children's Hospital | Akron | Ohio | 44308 | — |
| The Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15224 | — |
| Insitute for Exercise & Environmental Medicine | Dallas | Texas | 75231 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| University of Texas Medical School at Houston | Houston | Texas | 77030 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02255422, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 4, 2025 · Synced Jul 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02255422 live on ClinicalTrials.gov.