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Active, not recruiting Phase 3 Interventional Results available

An Efficacy and Safety Study of Apalutamide (JNJ-56021927) in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone in Participants With Chemotherapy-naive Metastatic Castration-resistant Prostate Cancer (mCRPC)

ClinicalTrials.gov ID: NCT02257736

Public ClinicalTrials.gov record NCT02257736. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 19, 2026, 6:25 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3 Randomized, Placebo-controlled Double-blind Study of JNJ-56021927 in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone in Subjects With Chemotherapy-naive Metastatic Castration-resistant Prostate Cancer (mCRPC)

Study identification

NCT ID
NCT02257736
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
Aragon Pharmaceuticals, Inc.
Industry
Enrollment
982 participants

Conditions and interventions

Interventions

  • Abiraterone acetate Drug
  • Apalutamide Drug
  • Placebo Drug
  • Prednisone Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
Male
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 25, 2014
Primary completion
Mar 18, 2018
Completion
Dec 30, 2027
Last update posted
May 10, 2026

2014 – 2027

United States locations

U.S. sites
46
U.S. states
22
U.S. cities
46
Facility City State ZIP Site status
Not listed Phoenix Arizona
Not listed La Mesa California
Not listed Los Angeles California
Not listed Modesto California
Not listed San Diego California
Not listed San Francisco California
Not listed Santa Barbara California
Not listed Aurora Colorado
Not listed Denver Colorado
Not listed Jensen Beach Florida
Not listed Lakeland Florida
Not listed New Port Richey Florida
Not listed Ocala Florida
Not listed Atlanta Georgia
Not listed Melrose Illinois
Not listed Niles Illinois
Not listed Marrero Louisiana
Not listed New Orleans Louisiana
Not listed Shreveport Louisiana
Not listed Auburn Maine
Not listed Baltimore Maryland
Not listed St Louis Missouri
Not listed Omaha Nebraska
Not listed Las Vegas Nevada
Not listed Albany New York
Not listed Johnson City New York
Not listed New York New York
Not listed Poughkeepsie New York
Not listed Syracuse New York
Not listed The Bronx New York
Not listed Columbus Ohio
Not listed Tualatin Oregon
Not listed Lancaster Pennsylvania
Not listed Pittsburgh Pennsylvania
Not listed Charleston South Carolina
Not listed Myrtle Beach South Carolina
Not listed Nashville Tennessee
Not listed Austin Texas
Not listed Houston Texas
Not listed Norfolk Virginia
Not listed Richmond Virginia
Not listed Auburn Washington
Not listed Seattle Washington
Not listed Spokane Washington
Not listed Wenatchee Washington
Not listed Madison Wisconsin

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 127 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02257736, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 10, 2026 · Synced May 19, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02257736 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →