SYN120 Study to Evaluate Its Safety, Tolerability and Efficacy in Parkinson's Disease Dementia (SYNAPSE)
Public ClinicalTrials.gov record NCT02258152. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
SYN120 a Dual 5-HT6/5-HT2A Antagonist Proof of Concept Study to Evaluate Its Safety, Tolerability and Efficacy in Parkinson's Disease Dementia (SYNAPSE)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study placebo-controlled, randomized, double-blind study is to assess the safety and efficacy of SYN120 in patients with Parkinson's disease dementia (PDD) already treated with a stable dose of a cholinesterase inhibitor.
Study identification
- NCT ID
- NCT02258152
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 82 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 22, 2014 (Actual)
- Primary completion
- Oct 3, 2017 (Actual)
- Completion
- Oct 3, 2017 (Actual)
- Last update posted
- Apr 19, 2019
2014 – 2017
United States locations
- U.S. sites
- 20
- U.S. states
- 16
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Banner Sun Health Research Institute | Sun City | Arizona | 85351 | — |
| UC San Diego | La Jolla | California | 92037 | — |
| Parkinson's Disease & Movement Disorder Center of Boca Raton | Boca Raton | Florida | 33486 | — |
| Augusta University | Augusta | Georgia | 29847 | — |
| Northwestern University, Feinberg School of Medicine | Chicago | Illinois | 60611 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| University of Iowa, Carver College of Medicine | Iowa City | Iowa | 52245 | — |
| Parkinson's Disease & Movement Disorder Center, University of Kansas Medical Center | Kansas City | Kansas | 66016 | — |
| Department of Neurology, University of Maryland Parkinson's Disease & Movement Disorder Center | Baltimore | Maryland | 21201 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Struthers Parkinson's Center | Golden Valley | Minnesota | 55427 | — |
| Atlantic Neuroscience Institute | Summit | New Jersey | 07901 | — |
| Duke University | Durham | North Carolina | 27705 | — |
| Wake Forest Baptist Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| Parkinson's Disease Movement Disorder Center | Philadelphia | Pennsylvania | 19107 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Baylor Univeristy | Houston | Texas | 77030 | — |
| Houston Methodist Neurological Institute/Movement Disorders Clinic | Houston | Texas | 77030 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02258152, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 19, 2019 · Synced Oct 3, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02258152 live on ClinicalTrials.gov.