A Feasibility Dose-escalating Study of MDT-10013 for Acute Postoperative Pain Following Total Knee Arthroplasty

ClinicalTrials.gov ID: NCT02263222

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Official title

A Feasibility Dose-escalating Study to Evaluate the Tolerability and Systemic Exposure of MDT-10013 Plus Routine Care in the Treatment of Acute Postoperative Pain Following Total Knee Arthroplasty

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is an open-label dose-escalating study to evaluate the tolerability and systemic exposure of MDT-10013 in men and women at least 18 years of age who are undergoing primary unilateral TKA.

Study identification

NCT ID: NCT02263222
Recruitment status: Withdrawn
Study type: Interventional
Phase: Phase 2
Lead sponsor: Medtronic Spinal and Biologics; Industry
Enrollment: Not listed

Conditions and interventions

Conditions

Post-operation Pain

Interventions

MDT-10013 Drug

Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Feb 2016 (Type not available)
Primary completion: Jun 2016 (Actual)
Completion: Jun 2016 (Actual)
Last update posted: Jun 7, 2016

2016

United States locations

U.S. sites: 3
U.S. states: 3
U.S. cities: 3

Facility	City	State	ZIP	Site status
Achieve Clinical Research, LLC	Birmingham	Alabama	35216	—
Florida Research Associates, LLC	DeLand	Florida	32720	—
Clinical Research Department, University of Orthopedics Center	Altoona	Pennsylvania	16602	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT02263222, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Jun 7, 2016 · Synced Nov 13, 2026