A Study to Evaluate Oral VT-1161 in the Treatment of Patients With Recurrent Vaginal Candidiasis (Yeast Infection)
Public ClinicalTrials.gov record NCT02267382. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study to Evaluate the Efficacy and Safety of VT-1161 Oral Tablets in the Treatment of Patients With Recurrent Vulvovaginal Candidiasis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
VT-1161 is a novel, oral inhibitor of fungal lanosterol demethylase (CYP51). In vitro and in vivo pharmacology studies have demonstrated that VT-1161 is highly active against Candida albicans and also non-albicans Candida species that cause vulvovaginal candidiasis. VT-1161 is highly selective for fungal CYP51, and data suggests that it may avoid the side-effect profile that limits the use of commonly prescribed antifungal agents for the treatment of recurrent yeast infections.
Study identification
- NCT ID
- NCT02267382
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 254 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 10, 2015 (Actual)
- Primary completion
- Nov 9, 2016 (Actual)
- Completion
- Nov 9, 2016 (Actual)
- Last update posted
- Oct 15, 2019
2015 – 2016
United States locations
- U.S. sites
- 32
- U.S. states
- 17
- U.S. cities
- 30
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama Birmingham | Birmingham | Alabama | 35233 | — |
| Precision Trials | Phoenix | Arizona | 85032 | — |
| NEA Baptist Clinic | Jonesboro | Arkansas | 72401 | — |
| Axis Clinical Trials | Los Angeles | California | 90017 | — |
| Axis Clinical Trials | Los Angeles | California | 90036 | — |
| Genesis Center for Clinical Research | San Diego | California | 92103 | — |
| Altus Research | Lake Worth | Florida | 33461 | — |
| Healthcare Clinical Data | Miami | Florida | 33161 | — |
| Community Medical Research | North Miami | Florida | 33181 | — |
| Vision Clinical Research | Palm Beach | Florida | 33414 | — |
| Physician Care Clinical Research LLC | Sarasota | Florida | 34239 | — |
| Clinical Research of West Florida | Tampa | Florida | 33603 | — |
| Cypress Medical Research Center | Wichita | Kansas | 67226 | — |
| Clinical Trials Management LLC | Covington | Louisiana | 70471 | — |
| Clinical Trials Management LLC | Metairie | Louisiana | 70006 | — |
| New England Center for Clinical Research | Fall River | Massachusetts | 02720 | — |
| Clinical Research of Nevada | Las Vegas | Nevada | 89123 | — |
| R. Garn Mabey, Jr. M.D. Chartered | Las Vegas | Nevada | 89128 | — |
| OB/GYN Clinical Research | Lawrenceville | New Jersey | 08648 | — |
| Women's Health Research Center | Plainsboro | New Jersey | 08536 | — |
| Suffolk OB-GYN | Port Jefferson | New York | 11777 | — |
| United Women's Clinical Research-Raleigh | Raleigh | North Carolina | 27607 | — |
| Lyndhurst Clinical Research | Winston-Salem | North Carolina | 27103 | — |
| Radiant Research | Akron | Ohio | 44311 | — |
| Drexel University College of Medicine | Philadelphia | Pennsylvania | 19102 | — |
| Magee Women's Hospital | Pittsburgh | Pennsylvania | 15213 | — |
| Brownstone Clinical Trials | Fort Worth | Texas | 76104 | — |
| TMC Life Research | Houston | Texas | 77054 | — |
| Brownstone Clinical Trials | Irving | Texas | 75062 | — |
| Clinical Trials of Texas | San Antonio | Texas | 78229 | — |
| Physician's Research Options LLC | Sandy City | Utah | 84020 | — |
| Seattle Women's Health Research Gynecology | Seattle | Washington | 98105 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02267382, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 15, 2019 · Synced Oct 24, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02267382 live on ClinicalTrials.gov.