Safety and Efficacy Study of CC-486 in Subjects With Myelodysplastic Syndromes
Public ClinicalTrials.gov record NCT02281084. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, International, Multicenter, Randomized, Open-label, Parallel Group to Evaluate the Efficacy and Safety of Cc-486 (Oral Azacitidine) Alone in Combination With Durvalumab (MEDI4736) in Subjects With Myelodysplastic Syndromes Who Fail to Achieve an Objective Response to Treatment With Azacitidine for Injection or Decitabine
Study identification
- NCT ID
- NCT02281084
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Celgene
- Industry
- Enrollment
- 65 participants
Conditions and interventions
Conditions
Interventions
- Oral Azacitidine Drug
- Durvalumab Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 5, 2015
- Primary completion
- Jun 18, 2019
- Completion
- Sep 13, 2023
- Last update posted
- Oct 3, 2024
2015 – 2023
United States locations
- U.S. sites
- 23
- U.S. states
- 10
- U.S. cities
- 14
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Local Institution - 113 | New Haven | Connecticut | 06520 | — |
| Yale University | New Haven | Connecticut | 06520 | — |
| University of Miami Miller School of Medicine | Miami | Florida | 33136 | — |
| H Lee Moffitt Cancer Center and Research Institute | Tampa | Florida | 33612 | — |
| Local Institution - 104 | Tampa | Florida | 33612 | — |
| Local Institution - 111 | Chicago | Illinois | 60637 | — |
| University of Chicago Medicine | Chicago | Illinois | 60637 | — |
| Ingalls Memorial Hospital | Harvey | Illinois | 60426-3558 | — |
| Local Institution - 109 | Harvey | Illinois | 60426-3558 | — |
| Local Institution - 116 | Iowa City | Iowa | 52242 | — |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | — |
| James Graham Brown Cancer Center | Louisville | Kentucky | 40202 | — |
| Local Institution - 103 | Louisville | Kentucky | 40202 | — |
| John Theurer Cancer Center at Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Local Institution - 102 | Hackensack | New Jersey | 07601 | — |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | — |
| Local Institution - 101 | New York | New York | 10029 | — |
| Local Institution - 110 | Philadelphia | Pennsylvania | 19104 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Hillman Cancer Institute at UPMC | Pittsburgh | Pennsylvania | 15232 | — |
| University of Texas- MD Anderson | Houston | Texas | 77030 | — |
| Cancer Care Centers of South Texas - HOAST | San Antonio | Texas | 78229 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 66 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02281084, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 3, 2024 · Synced Jul 21, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02281084 live on ClinicalTrials.gov.