A Study to Evaluate Efficacy and Safety of Lifitegrast in Subjects With Dry Eye (OPUS-3)
Public ClinicalTrials.gov record NCT02284516. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multicenter, Randomized, Double-masked, and Placebo-controlled Study Evaluating the Efficacy and Safety of a 5.0% Concentration of Lifitegrast Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye Disease and History of Recent Artificial Tear Use
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Evaluate the efficacy and safety of Lifitegrast in subjects with dry eye disease and a recent history of artificial tear use.
Study identification
- NCT ID
- NCT02284516
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 711 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 6, 2014 (Actual)
- Primary completion
- Oct 5, 2015 (Actual)
- Completion
- Oct 5, 2015 (Actual)
- Last update posted
- Jun 11, 2021
2014 – 2015
United States locations
- U.S. sites
- 41
- U.S. states
- 15
- U.S. cities
- 36
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham, UAB School of Optometry | Birmingham | Alabama | 35294 | — |
| Arizona Eye Center | Chandler | Arizona | 85225 | — |
| Sall Research Medical Center | Artesia | California | 90701 | — |
| United Medical Research Institute | Inglewood | California | 90301 | — |
| North Valley Eye Medical Group, Inc | Mission Hills | California | 91345 | — |
| Montebello Medical Eye Center, Inc. | Montebello | California | 90640 | — |
| Eye Research Foundation | Newport Beach | California | 92663 | — |
| Arch Health Partners | Poway | California | 92064 | — |
| Martel Eye Medical Group | Rancho Cordova | California | 95670 | — |
| Shasta Eye Medical Group, Inc. | Redding | California | 96001 | — |
| West Coast Eye Care Associates | San Diego | California | 92115 | — |
| Chicago Cornea Consultants, Ltd. | Hoffman Estates | Illinois | 60169 | — |
| Jackson Eye, SC | Lake Villa | Illinois | 60046 | — |
| Price Vision Group | Indianapolis | Indiana | 46260 | — |
| John-Kenyon American Eye Institute | New Albany | Indiana | 47150 | — |
| Koffler Vision Group | Lexington | Kentucky | 40509 | — |
| The Eye Care Institute | Louisville | Kentucky | 40206 | — |
| Holpro Vision, Ltd. | Union | Kentucky | 41091 | — |
| Clinical Eye Research of Boston | Winchester | Massachusetts | 01890 | — |
| Lifelong Vision Foundation | Chesterfield | Missouri | 63017 | — |
| Tauber Eye Center | Kansas City | Missouri | 64111 | — |
| Tekwani Vision Center | St Louis | Missouri | 63128 | — |
| Ophthalmology Consultants, Ltd. | St Louis | Missouri | 63131 | — |
| Comprehensive Eye Care, Ltd. | Washington | Missouri | 63090 | — |
| Wellish Vision Institute | Las Vegas | Nevada | 89119 | — |
| Abrams Eye Institute | Las Vegas | Nevada | 89148 | — |
| Clinical Vision Research Center at SUNY | New York | New York | 10036 | — |
| Ophthalmic Consultants Of Long Island | Rockville Centre | New York | 11570 | — |
| South Shore Eye Care, LLP | Wantagh | New York | 11793 | — |
| Abrams Eye Center | Cleveland | Ohio | 44115 | — |
| Scott & Christie and Associates, PC | Cranberry Township | Pennsylvania | 16066 | — |
| Matossian Eye Associates | Doylestown | Pennsylvania | 18902 | — |
| Toyos Clinic | Nashville | Tennessee | 37203 | — |
| The Cataract & Glaucoma Center | El Paso | Texas | 79902 | — |
| Advanced Laser Vision and Surgical Institute | Houston | Texas | 77034 | — |
| Whitsett Vision Group | Houston | Texas | 77056 | — |
| University of Houston College of Optometry | Houston | Texas | 77204 | — |
| The Eye Clinic of Texas (Houston Eye Associates) | League City | Texas | 77573 | — |
| Eye Clinics of South Texas, P.A. | San Antonio | Texas | 78209 | — |
| R and R Eye Research, LLC. | San Antonio | Texas | 78229 | — |
| See Clearly Vision | McLean | Virginia | 22012 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02284516, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 11, 2021 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02284516 live on ClinicalTrials.gov.