AD-4833/TOMM40_303 Extension Study of the Safety and Efficacy of Pioglitazone to Slow Cognitive Decline in Participants With Mild Cognitive Impairment Due to Alzheimer Disease
Public ClinicalTrials.gov record NCT02284906. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Blinded Long-term Extension Study to Evaluate the Safety and Efficacy of Pioglitazone (AD-4833 Sustained Release 0.8 mg Daily) to Slow the Progression of Cognitive Decline in Subjects Who Have Completed the AD-4833/TOMM40_301 Study With Diagnosis of Mild Cognitive Impairment Due to Alzheimer Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the effect of pioglitazone at 24 months compared with placebo on cognitive decline in high-risk participants who have completed the AD-4833/TOMM40\_301 study \[NCT01931566\] with an adjudicated diagnosis of mild cognitive impairment (MCI) due to Alzheimer's Disease (AD).
Study identification
- NCT ID
- NCT02284906
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 40 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 65 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 12, 2015 (Actual)
- Primary completion
- Jan 31, 2018 (Actual)
- Completion
- May 8, 2018 (Actual)
- Last update posted
- Jul 2, 2019
2015 – 2018
United States locations
- U.S. sites
- 28
- U.S. states
- 16
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Phoenix | Arizona | 85006 | — |
| Not listed | Sun City | Arizona | 85351 | — |
| Not listed | San Diego | California | 92103 | — |
| Not listed | Delray Beach | Florida | 33445 | — |
| Not listed | Fort Myers | Florida | 33912 | — |
| Not listed | Lake Worth | Florida | 33449 | — |
| Not listed | Melbourne | Florida | 32940 | — |
| Not listed | Merritt Island | Florida | 32952 | — |
| Not listed | Port Orange | Florida | 32127 | — |
| Not listed | St. Petersburg | Florida | 33709 | — |
| Not listed | Weston | Florida | 33331 | — |
| Not listed | Atlanta | Georgia | 30329 | — |
| Not listed | Decatur | Georgia | 30033 | — |
| Not listed | Chicago | Illinois | 60640 | — |
| Not listed | Elk Grove | Illinois | 60007 | — |
| Not listed | Elk Grove Village | Illinois | 60007 | — |
| Not listed | Iowa City | Iowa | 52242 | — |
| Not listed | St Louis | Missouri | 63141 | — |
| Not listed | Las Vegas | Nevada | 89106 | — |
| Not listed | Marlton | New Jersey | 08053 | — |
| Not listed | New York | New York | 10019 | — |
| Not listed | Concord | North Carolina | 28025 | — |
| Not listed | Durham | North Carolina | 27705 | — |
| Not listed | Akron | Ohio | 44320 | — |
| Not listed | Charleston | South Carolina | 29401 | — |
| Not listed | Houston | Texas | 77030 | — |
| Not listed | Salt Lake City | Utah | 84107 | — |
| Not listed | Middleton | Wisconsin | 53562 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 15 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02284906, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 2, 2019 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02284906 live on ClinicalTrials.gov.