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Completed Phase 2 Interventional Results available

A Study of Lampalizumab Intravitreal Injections Administered Every Two Weeks or Every Four Weeks to Participants With Geographic Atrophy

ClinicalTrials.gov ID: NCT02288559

Public ClinicalTrials.gov record NCT02288559. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 2:46 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II, Multicenter, Randomized, Single-Masked, Sham Injection-Controlled Exposure-Response Study of Lampalizumab Intravitreal Injections Administered Every Two Weeks or Every Four Weeks to Patients With Geographic Atrophy

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This multicenter, randomized, single-masked, sham injection-controlled study will investigate the exposure-response and safety of lampalizumab administered intravitreally every 2 weeks (Q2W) or every 4 weeks (Q4W) for 24 weeks in participants with geographic atrophy (GA) secondary to age-related macular degeneration (AMD). A safety run-in assessment will be conducted prior to initiating enrollment in the randomized study.

Study identification

NCT ID
NCT02288559
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Genentech, Inc.
Industry
Enrollment
96 participants

Conditions and interventions

Interventions

Other · Drug

Eligibility (public fields only)

Age range
60 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 29, 2015
Primary completion
Jun 1, 2017
Completion
Jun 1, 2017
Last update posted
Sep 24, 2019

2015 – 2017

United States locations

U.S. sites
36
U.S. states
19
U.S. cities
36
Facility City State ZIP Site status
Barnet Dulaney Perkins Eye Center Mesa Arizona 85206
University of Arizona; Banner University Medical, Department of Opthalmology Tucson Arizona 85711
Northwest Arkansas Retina Associates Springdale Arkansas 72764
Retinal Diagnostic Center Campbell California 95008
The Retina Partners Encino California 91436
Loma Linda University Loma Linda California 92354
San Diego Retina Associates Oceanside California 92056
West Coast Retina Medical Group San Francisco California 94109
California Retina Consultants Santa Barbara California 93103
Colorado Retina Associates, PC Golden Colorado 80401
Florida Eye Microsurgical Inst Boynton Beach Florida 33426
National Ophthalmic Research Institute Fort Myers Florida 33912
Florida Eye Associates Melbourne Florida 32901
Retina Care Specialists Palm Beach Gardens Florida 33410
Retina Specialty Institute Pensacola Florida 32503
Rush University Medical Center Chicago Illinois 60612
Wolfe Eye Clinic West Des Moines Iowa 50266
Elman Retina Group Baltimore Maryland 21237
Vitreoretinal Surgery Edina Minnesota 55435
The Retina Institute St Louis Missouri 63128
Sierra Eye Associates Reno Nevada 89502
Eye Associates of New Mexico Albuquerque New Mexico 87102
Western Carolina Retinal Associate PA Asheville North Carolina 28803
Char Eye Ear &Throat Assoc Charlotte North Carolina 28210
Cincinnati Eye Institute Cincinnati Ohio 45242
Retina Assoc of Cleveland Inc Cleveland Ohio 44122
Dean McGee Eye Institute Oklahoma City Oklahoma 73099
Retina Cons of Charleston Charleston South Carolina 29414
Carolina Retina Center PA Columbia South Carolina 29223
Charles Retina Institution Germantown Tennessee 38138
Southeastern Retina Associates Knoxville Tennessee 37923
Tennessee Retina PC. Nashville Tennessee 37203
W Texas Retina Consultants PA Abilene Texas 79606
Texas Retina Associates Dallas Texas 75231
Retina Specialists DeSoto Texas 75115
Wagner Macula & Retina Center Norfolk Virginia 23451

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02288559, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 24, 2019 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02288559 live on ClinicalTrials.gov.

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