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Completed Phase 2 Interventional Results available

Study of Gemcitabine, Abraxane® Plus Placebo Versus Gemcitabine, Abraxane® Plus 1 or 2 Truncated Courses of Demcizumab in Subjects With 1st-Line Metastatic Pancreatic Ductal Adenocarcinoma

ClinicalTrials.gov ID: NCT02289898

Public ClinicalTrials.gov record NCT02289898. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 24, 2026, 4:55 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A 3-Arm Phase 2 Double-Blind Randomized Study of Gemcitabine, Abraxane® Plus Placebo Versus Gemcitabine, Abraxane® Plus 1 or 2 Truncated Courses of Demcizumab in Subjects With 1st-Line Metastatic Pancreatic Ductal Adenocarcinoma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a randomized, double blind, 3 arm (1:1:1) study in subjects with 1st-line metastatic pancreatic ductal adenocarcinoma. The purpose is to test the efficacy and safety of demcizumab, when given in combination with gemcitabine and Abraxane® compared to placebo. The administration of gemcitabine and Abraxane® is a standard treatment for patients with metastatic pancreatic ductal adenocarcinoma.

Study identification

NCT ID
NCT02289898
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
OncoMed Pharmaceuticals, Inc.
Industry
Enrollment
207 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
21 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 20, 2015 (Actual)
Primary completion
May 2017 (Actual)
Completion
Sep 2017 (Actual)
Last update posted
Sep 28, 2020

2015 – 2017

United States locations

U.S. sites
22
U.S. states
15
U.S. cities
22
Facility City State ZIP Site status
Banner MD Anderson Cancer Center Gilbert Arizona 85234 —
Providence Saint Joseph Medical Center Burbank California 91505 —
City of Hope Duarte California 91010 —
Scripps Cancer Center La Jolla California 92037 —
University of California, Davis Comprehensive Cancer Center Sacramento California 95817 —
Soulhern California Permanente Medical Group San Marcos California 92078 —
Kaiser Permanente Medical Center Vallejo California 94589 —
Rocky Mountain Cancer Centers Denver Colorado 80218 —
Lynn Cancer Institute Boca Raton Florida 33486 —
University of Iowa Hospitals and Clinics Iowa City Iowa 52242 —
University of Kansas Cancer Center Westwood Kansas 66205 —
Ochsner Clinic Foundation New Orleans Louisiana 70121 —
University of Michigan Ann Arbor Michigan 48109 —
Dartmouth Hitchcock Medical Center, Norris Cotton Cancer Center Lebanon New Hampshire 03756 —
University of Rochester Rochester New York 14642 —
SUNY Upstate Medical University Syracuse New York 13210 —
Cleveland Clinic Cleveland Ohio 44195 —
Kaiser Permanente NW Oncology Research Portland Oregon 97227 —
Thomas Jefferson University, Sydney Kimmel Cancer Center Philadelphia Pennsylvania 19107 —
Baylor College of Medicine Houston Texas 77030 —
Joe Arrington Cancer Research Treatment Center Lubbock Texas 79410 —
Huntsman Cancer Institute at The University of Utah Salt Lake City Utah 84112 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 20 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02289898, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 28, 2020 · Synced Oct 24, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02289898 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →