ClinicalTrials.gov record
Trial of Linaclotide in Patients With Chronic Idiopathic Constipation
ClinicalTrials.gov ID: NCT02291679
Public ClinicalTrials.gov record NCT02291679. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-blind, Placebo-controlled, Parallel-group Trial of Linaclotide (72 ug or 145 ug) Administered Orally for 12 Weeks to Patients With Chronic Idiopathic Constipation
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The objective of this trial was to determine the efficacy and safety of linaclotide 72 ug administered once daily to patients with chronic idiopathic constipation (CIC). The primary efficacy parameter is the percentage of participants in each dosing group that meet the protocol definition for complete spontaneous bowel movement (CSBM) Overall Responder.
Study identification
- NCT ID
- NCT02291679
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,223 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 2014 (Type not available)
- Primary completion
- Aug 2015 (Actual)
- Completion
- Aug 2015 (Actual)
- Last update posted
- Jun 15, 2017
2014 – 2015
United States locations
- U.S. sites
- 95
- U.S. states
- 30
- U.S. cities
- 84
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Ironwood Investigational Site | Huntsville | Alabama | 35801 | — |
| Ironwood Investigational Site | Phoenix | Arizona | 85018 | — |
| Ironwood Investigational Site | Tucson | Arizona | 85712 | — |
| Ironwood Investigational Site | North Little Rock | Arkansas | 72117 | — |
| Ironwood Investigational Site | Anaheim | California | 92801 | — |
| Ironwood Investigational Site | Chula Vista | California | 91910 | — |
| Ironwood Investigational Site | Garden Grove | California | 92843 | — |
| Ironwood Investigational Site | La Mesa | California | 91942 | — |
| Ironwood Investigational Site | North Hollywood | California | 91606 | — |
| Ironwood Investigational Site | Orange | California | 92868 | — |
| Ironwood Investigational Site | San Diego | California | 92108 | — |
| Ironwood Investigational Site | Thousand Oaks | California | 91360 | — |
| Ironwood Investigational Site | Colorado Springs | Colorado | 80904 | — |
| Ironwood Investigational Site | Bristol | Connecticut | 06010 | — |
| Ironwood Investigational Site | Boynton Beach | Florida | 33426 | — |
| Ironwood Investigational Site | Coral Gables | Florida | 33134 | — |
| Ironwood Investigational Site | DeLand | Florida | 32720 | — |
| Ironwood Investigational Site | Hialeah | Florida | 33016 | — |
| Ironwood Investigational Site | Inverness | Florida | 34452 | — |
| Ironwood Investigational Site | Jupiter | Florida | 33458 | — |
| Ironwood Investigational Site | Kissimmee | Florida | 34741 | — |
| Ironwood Investigational Site | Lauderdale Lakes | Florida | 33319 | — |
| Ironwood Investigational Site | Miami | Florida | 33015 | — |
| Ironwood Investigational Site | Miami | Florida | 33126 | — |
| Ironwood Investigational Site | Miami | Florida | 33133 | — |
| Ironwood Investigational Site | Miami | Florida | 33135 | — |
| Ironwood Investigational Site | Miami | Florida | 33165 | — |
| Ironwood Investigational Site | Miami | Florida | 33175 | — |
| Ironwood Investigational Site | Orlando | Florida | 32806 | — |
| Ironwood Investigational Site | Ormond Beach | Florida | 32174 | — |
| Ironwood Investigational Site | Port Orange County | Florida | 32129 | — |
| Ironwood Investigational Site | South Miami | Florida | 33143 | — |
| Ironwood Investigational Site | Tampa | Florida | 33634 | — |
| Ironwood Investigational Site | West Palm Beach | Florida | 33409 | — |
| Ironwood Investigational Site | Winter Park | Florida | 32792 | — |
| Ironwood Investigational Site | Atlanta | Georgia | 30328 | — |
| Ironwood Investigational Site | Oakwood | Georgia | 30566 | — |
| Ironwood Investigational Site | Sandy Springs | Georgia | 30328 | — |
| Ironwood Investigational Site | Evansville | Indiana | 47714 | — |
| Ironwood Investigational Site | Bastrop | Louisiana | 71220 | — |
| Ironwood Investigational Site | Metairie | Louisiana | 70006 | — |
| Ironwood Investigational Site | Shreveport | Louisiana | 71103 | — |
| Ironwood Investigational Site | Baltimore | Maryland | 21215 | — |
| Ironwood Investigational Site | Chevy Chase | Maryland | 20815 | — |
| Ironwood Investigational Site | Hagerstown | Maryland | 21740 | — |
| Ironwood Investigational Site | Hollywood | Maryland | 20636 | — |
| Ironwood Investigational Site | Boston | Massachusetts | 02135 | — |
| Ironwood Investigational Site | Wellesley | Massachusetts | 02481 | — |
| Ironwood Investigational Site | Chesterfield | Michigan | 48047 | — |
| Ironwood Investigational Site | Troy | Michigan | 48098 | — |
| Ironwood Investigational Site | Wyoming | Michigan | 49519 | — |
| Ironwood Investigational Site | Jackson | Mississippi | 39202 | — |
| Ironwood Investigational Site | St Louis | Missouri | 63128 | — |
| Ironwood Investigational Site | Bozeman | Montana | 59718 | — |
| Ironwood Investigational Site | Las Vegas | Nevada | 89119 | — |
| Ironwood Investigational Site | Las Vegas | Nevada | 89121 | — |
| Ironwood Investigational Site | Brooklyn | New York | 11206 | — |
| Ironwood Investigational Site | Endwell | New York | 13760 | — |
| Ironwood Investigational Site | Great Neck | New York | 11023 | — |
| Ironwood Investigational Site | Charlotte | North Carolina | 28209 | — |
| Ironwood Investigational Site | Charlotte | North Carolina | 28226 | — |
| Ironwood Investigational Site | Greensboro | North Carolina | 27403 | — |
| Ironwood Investigational Site | High Point | North Carolina | 27262 | — |
| Ironwood Investigational Site | Lenoir | North Carolina | 28645 | — |
| Ironwood Investigational Site | Raleigh | North Carolina | 27612 | — |
| Ironwood Investigational Site | Wilmington | North Carolina | 28401 | — |
| Ironwood Investigational Site | Winston-Salem | North Carolina | 27103 | — |
| Ironwood Investigational Site | Fargo | North Dakota | 58103 | — |
| Ironwood Investigational Site | Cincinnati | Ohio | 45219 | — |
| Ironwood Investigational Site | Cincinnati | Ohio | 45224 | — |
| Ironwood Investigational Site | Columbus | Ohio | 43214 | — |
| Ironwood Investigational Site | Mentor | Ohio | 44060 | — |
| Ironwood Investigational Site | Sylvania | Ohio | 43560 | — |
| Ironwood Investigational Site | Oklahoma City | Oklahoma | 73112 | — |
| Ironwood Investigational Site | Levittown | Pennsylvania | 19056 | — |
| Ironwood Investigational Site | Anderson | South Carolina | 29621 | — |
| Ironwood Investigational Site | Greer | South Carolina | 29651 | — |
| Ironwood Investigational Site | Simpsonville | South Carolina | 29681 | — |
| Ironwood Investigational Site | Dakota Dunes | South Dakota | 57049 | — |
| Ironwood Investigational Site | Bristol | Tennessee | 37620 | — |
| Ironwood Investigational Site | Chattanooga | Tennessee | 37421 | — |
| Ironwood Investigational Site | Knoxville | Tennessee | 37919 | — |
| Ironwood Investigational Site | Beaumont | Texas | 77701 | — |
| Ironwood Investigational Site | Dallas | Texas | 75230 | — |
| Ironwood Investigational Site | El Paso | Texas | 79905 | — |
| Ironwood Investigational Site | Houston | Texas | 77074 | — |
| Ironwood Investigational Site | Houston | Texas | 77098 | — |
| Ironwood Investigational Site | Longview | Texas | 75605 | — |
| Ironwood Investigational Site | San Antonio | Texas | 78209 | — |
| Ironwood Investigational Site | San Antonio | Texas | 78229 | — |
| Ironwood Investigational Site | San Antonio | Texas | 78258 | — |
| Ironwood Investigational Site | South Ogden | Utah | 84405 | — |
| Ironwood Investigational Site | Christiansburg | Virginia | 24073 | — |
| Ironwood Investigational Site | Lynchburg | Virginia | 24502 | — |
| Ironwood Investigational Site | La Crosse | Wisconsin | 54601 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02291679, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 15, 2017 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02291679 live on ClinicalTrials.gov.