A Phase II Randomized Study Evaluating the Biological and Clinical Effects of the Combination of Palbociclib With Letrozole as Neoadjuvant Therapy in Post-Menopausal Women With Estrogen-Receptor Positive Primary Breast Cancer
Public ClinicalTrials.gov record NCT02296801. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will look at effects the combination of palbociclib and letrozole may have on estrogen receptor (ER)-positive/human epidermal growth factor receptor 2 (HER2)-negative breast cancer tumors which have not yet been treated. Letrozole is a type of endocrine therapy called an aromatase inhibitor (AI) and is standard treatment for post-menopausal women with ER-positive/HER2-negative breast cancer.
Study identification
- NCT ID
- NCT02296801
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 307 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 2015 (Type not available)
- Primary completion
- Jul 2018 (Actual)
- Completion
- Mar 2019 (Actual)
- Last update posted
- Jan 13, 2022
2015 – 2019
United States locations
- U.S. sites
- 19
- U.S. states
- 13
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Long Beach Memorial Medical Center-Todd Cancer Institute | Long Beach | California | 90806 | — |
| University of Miami Hospital and Clinics - Sylvester Comprehensive Cancer Center | Miami | Florida | 33136 | — |
| Cancer Care Specialists of Central Illinois | Decatur | Illinois | 62526 | — |
| Norton Healthcare Pavillion | Louisville | Kentucky | 40202 | — |
| Norton Cancer Institute - Suburban, Norton Medical Plaza II | Louisville | Kentucky | 40207 | — |
| Norton Cancer Institute - Brownsboro Medical Plaza I | Louisville | Kentucky | 40241 | — |
| Metro-Minnesota CCOP | Saint Louis Park | Minnesota | 55416 | — |
| Hope Women's Cancer Centers | Asheville | North Carolina | 28806 | — |
| Providence Oncology and Hematology Clinic | Portland | Oregon | 97213 | — |
| Pinnacle Health Ortenzio Cancer Center | Mechanicsburg | Pennsylvania | 17050 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15215 | — |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15232 | — |
| Women and Infants Hospital of Rhode Island | Providence | Rhode Island | 02905 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Joe Arrington Cancer Research and Treatment Center | Lubbock | Texas | 79410 | — |
| Sentara Martha Jefferson Hospital-Phillips Family Cancer Center | Charlottesville | Virginia | 22911 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23298 | — |
| Swedish Cancer Institute | Seattle | Washington | 98104 | — |
| West Virginia University | Morgantown | West Virginia | 26506 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 33 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02296801, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 13, 2022 · Synced Nov 2, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02296801 live on ClinicalTrials.gov.