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Completed Phase 3 Interventional Results available

The COMPASS Study: A Study of Volanesorsen (Formally ISIS-APOCIIIRx) in Patients With Hypertriglyceridemia

ClinicalTrials.gov ID: NCT02300233

Public ClinicalTrials.gov record NCT02300233. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 19, 2026, 2:55 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

The COMPASS Study: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of ISIS 304801 Administered Subcutaneously to Patients With Hypertriglyceridemia

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the efficacy and safety of volanesorsen given for 26 weeks in participants with Hypertriglyceridemia.

Study identification

NCT ID
NCT02300233
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Ionis Pharmaceuticals, Inc.
Industry
Enrollment
114 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 5, 2015 (Actual)
Primary completion
Jul 27, 2016 (Actual)
Completion
Jan 24, 2017 (Actual)
Last update posted
Apr 13, 2022

2015 – 2017

United States locations

U.S. sites
29
U.S. states
17
U.S. cities
28
Facility City State ZIP Site status
IONIS Investigative Site Encinitas California 92024 —
IONIS Investigative Site San Francisco California 94143 —
IONIS Investigative Site Boca Raton Florida 33434 —
IONIS Investigative Site Miami Florida 33147 —
IONIS Investigative Site Sterling Illinois 61081 —
IONIS Investigative Site Kansas City Kansas 66160 —
IONIS Investigative Site Salisbury Maryland 73103 —
IONIS Investigative Site Towson Maryland 21204 —
IONIS Investigative Site Boston Massachusetts 02114 —
IONIS Investigative Site Grandville Michigan 49418 —
IONIS Investigative Site North Massapequa New York 11758-1802 —
IONIS Investigative Site Benson North Carolina 27504 —
IONIS Investigative Site Chapel Hill North Carolina 27609 —
IONIS Investigative Site Farmville North Carolina 27828 —
IONIS Investigative Site Greenville North Carolina 27834 —
IONIS Investigative Site Morrisville North Carolina 27560 —
IONIS Investigative Site Raleigh North Carolina 27612 —
IONIS Investigative Site Wilson North Carolina 27609 —
IONIS Investigative Site Wilson North Carolina 27893 —
IONIS Investigative Site Cincinnati Ohio 45227 —
IONIS Investigative Site Kettering Ohio 45429 —
IONIS Investigative Site Marion Ohio 43302 —
IONIS Investigative Site Oklahoma City Oklahoma 73103 —
IONIS Investigative Site Portland Oregon 97239 —
IONIS Investigative Site Providence Rhode Island 02906 —
IONIS Investigative Site Houston Texas 77030 —
IONIS Investigative Site Salt Lake City Utah 84108 —
IONIS Investigative Site Norfolk Virginia 23510 —
IONIS Investigative Site Seattle Washington 98104 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 16 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02300233, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 13, 2022 · Synced Oct 19, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02300233 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →