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Completed Phase 3 Interventional Results available

The COMPASS Study: A Study of Volanesorsen (Formally ISIS-APOCIIIRx) in Patients With Hypertriglyceridemia

ClinicalTrials.gov ID: NCT02300233

Public ClinicalTrials.gov record NCT02300233. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 2:02 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

The COMPASS Study: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of ISIS 304801 Administered Subcutaneously to Patients With Hypertriglyceridemia

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the efficacy and safety of volanesorsen given for 26 weeks in participants with Hypertriglyceridemia.

Study identification

NCT ID
NCT02300233
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Ionis Pharmaceuticals, Inc.
Industry
Enrollment
114 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 4, 2015
Primary completion
Jul 26, 2016
Completion
Jan 23, 2017
Last update posted
Apr 12, 2022

2015 – 2017

United States locations

U.S. sites
29
U.S. states
17
U.S. cities
28
Facility City State ZIP Site status
IONIS Investigative Site Encinitas California 92024
IONIS Investigative Site San Francisco California 94143
IONIS Investigative Site Boca Raton Florida 33434
IONIS Investigative Site Miami Florida 33147
IONIS Investigative Site Sterling Illinois 61081
IONIS Investigative Site Kansas City Kansas 66160
IONIS Investigative Site Salisbury Maryland 73103
IONIS Investigative Site Towson Maryland 21204
IONIS Investigative Site Boston Massachusetts 02114
IONIS Investigative Site Grandville Michigan 49418
IONIS Investigative Site North Massapequa New York 11758-1802
IONIS Investigative Site Benson North Carolina 27504
IONIS Investigative Site Chapel Hill North Carolina 27609
IONIS Investigative Site Farmville North Carolina 27828
IONIS Investigative Site Greenville North Carolina 27834
IONIS Investigative Site Morrisville North Carolina 27560
IONIS Investigative Site Raleigh North Carolina 27612
IONIS Investigative Site Wilson North Carolina 27609
IONIS Investigative Site Wilson North Carolina 27893
IONIS Investigative Site Cincinnati Ohio 45227
IONIS Investigative Site Kettering Ohio 45429
IONIS Investigative Site Marion Ohio 43302
IONIS Investigative Site Oklahoma City Oklahoma 73103
IONIS Investigative Site Portland Oregon 97239
IONIS Investigative Site Providence Rhode Island 02906
IONIS Investigative Site Houston Texas 77030
IONIS Investigative Site Salt Lake City Utah 84108
IONIS Investigative Site Norfolk Virginia 23510
IONIS Investigative Site Seattle Washington 98104

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 16 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02300233, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 12, 2022 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02300233 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →