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Completed Phase 1 Interventional

Alisertib and Combination Chemotherapy in Treating Patients With Gastrointestinal Tumors

ClinicalTrials.gov ID: NCT02319018

Public ClinicalTrials.gov record NCT02319018. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 15, 2026, 11:49 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1 Study of Alisertib (MLN8237) in Combination With mFOLFOX in Gastrointestinal Tumors

Study identification

NCT ID
NCT02319018
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
National Cancer Institute (NCI)
NIH
Enrollment
14 participants

Conditions and interventions

Interventions

  • Alisertib Drug
  • Fluorouracil Drug
  • Laboratory Biomarker Analysis Other
  • Leucovorin Calcium Drug
  • Oxaliplatin Drug

Drug · Other

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 26, 2015
Primary completion
Sep 28, 2018
Completion
Sep 28, 2018
Last update posted
Oct 8, 2018

2015 – 2018

United States locations

U.S. sites
5
U.S. states
4
U.S. cities
4
Facility City State ZIP Site status
Smilow Cancer Center/Yale-New Haven Hospital New Haven Connecticut 06510
Yale University New Haven Connecticut 06520
Johns Hopkins University/Sidney Kimmel Cancer Center Baltimore Maryland 21287
Wayne State University/Karmanos Cancer Institute Detroit Michigan 48201
Vanderbilt University/Ingram Cancer Center Nashville Tennessee 37232

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02319018, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 8, 2018 · Synced May 15, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02319018 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →