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Completed Phase 2 Interventional Results available

Phase II Study of MEDI4736, Tremelimumab, and MEDI4736 in Combination w/ Tremelimumab Squamous Cell Carcinoma of the Head and Neck

ClinicalTrials.gov ID: NCT02319044

Public ClinicalTrials.gov record NCT02319044. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 23, 2026, 6:21 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II, Randomized, Open-Label, Multi-Center, Global Study of MEDI4736 Monotherapy, Tremelimumab Monotherapy, and MEDI4736 in Combination With Tremelimumab in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN)

Study identification

NCT ID
NCT02319044
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
AstraZeneca
Industry
Enrollment
267 participants

Conditions and interventions

Interventions

  • MEDI4736 Drug
  • Tremelimumab Drug
  • MEDI4736 + Tremelimumab Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 96 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 14, 2015
Primary completion
Sep 25, 2016
Completion
Jul 5, 2020
Last update posted
Sep 28, 2020

2015 – 2020

United States locations

U.S. sites
43
U.S. states
24
U.S. cities
41
Facility City State ZIP Site status
Research Site Birmingham Alabama 35294
Research Site Yuma Arizona 85364
Research Site Little Rock Arkansas 72205
Research Site Downey California 90241
Research Site Duarte California 91010-3012
Research Site La Jolla California 92093
Research Site Long Beach California 90813
Research Site Los Angeles California 90033
Research Site Los Angeles California 90095
Research Site San Francisco California 94115
Research Site Aurora Colorado 80045
Research Site Tampa Florida 33612
Research Site Atlanta Georgia 30322
Research Site Augusta Georgia 30912
Research Site Macon Georgia 31201
Research Site Chicago Illinois 60637
Research Site Evanston Illinois 60201
Research Site Lexington Kentucky 40536-0001
Research Site Baltimore Maryland 21201
Research Site Baltimore Maryland 21204
Research Site Boston Massachusetts 02215
Research Site Ann Arbor Michigan 48109
Research Site Detroit Michigan 48201
Research Site Southfield Michigan 48075
Research Site Rochester Minnesota 55905-0001
Research Site St Louis Missouri 63110
Research Site Lebanon New Hampshire 03756
Research Site New York New York 10032
Research Site Stony Brook New York 11794
Research Site The Bronx New York 10467
Research Site Durham North Carolina 27705
Research Site Winston-Salem North Carolina 27157
Research Site Portland Oregon 97239
Research Site Bethlehem Pennsylvania 18015
Research Site Pittsburgh Pennsylvania 15232
Research Site Charleston South Carolina 29425
Research Site Knoxville Tennessee 37909
Research Site Nashville Tennessee 37232
Research Site Arlington Texas 76012
Research Site Austin Texas 78701
Research Site Dallas Texas 75230
Research Site Morgantown West Virginia 26506
Research Site Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 82 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02319044, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 28, 2020 · Synced Jul 23, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02319044 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →