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Completed Phase 1 Interventional Results available

A Study MLN2480 in Combination With MLN0128 or Alisertib, or Paclitaxel, or Cetuximab, or Irinotecan in Adult Participants With Advanced Nonhematologic Malignancies

ClinicalTrials.gov ID: NCT02327169

Public ClinicalTrials.gov record NCT02327169. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 5, 2026, 11:46 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multiarm, Open-label, Phase 1b Study of MLN2480 (an Oral A-, B-, and CRAF Inhibitor) in Combination With MLN0128 (an Oral mTORC 1/2 Inhibitor), or Alisertib (an Oral Aurora A Kinase Inhibitor), or Paclitaxel, or Cetuximab, or Irinotecan, in Adult Patients With Advanced Nonhematologic Malignancies

Study identification

NCT ID
NCT02327169
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Millennium Pharmaceuticals, Inc.
Industry
Enrollment
81 participants

Conditions and interventions

Interventions

  • Alisertib Drug
  • Cetuximab Drug
  • Irinotecan Drug
  • MLN0128 Drug
  • MLN2480 Drug
  • Paclitaxel Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 13, 2015
Primary completion
Jul 1, 2018
Completion
Jul 1, 2018
Last update posted
Feb 24, 2020

2015 – 2018

United States locations

U.S. sites
5
U.S. states
3
U.S. cities
3
Facility City State ZIP Site status
Massachusetts General Hospital Cancer Center Boston Massachusetts 2114
Beth Israel Deaconess Medical Center Boston Massachusetts 2115
Dana Farber Cancer Institute Boston Massachusetts 2115
Fox Chase Cancer Center Philadelphia Pennsylvania 19111
The University of Texas MD Anderson Cancer Center Houston Texas 77030

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 9 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02327169, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 24, 2020 · Synced May 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02327169 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →